Antonia Panescu

Computational Biology PhD @Yale MBiochem @UniofOxford | @BerkeleyLab for the summer

[Eterna @eternagame]

Major props @DidiKieran @jgkoob @lemerleau @IIMCB_Poland @FrankRHutter @AF_Panescu @chaitjo @rishabh16_ for generating 600,000 sequences to fold into 1000 synthetic pseudoknots! The wet lab results will help these researchers improve their computational methods for RNA design.

[Antonia Panescu @AF_Panescu]

📄 Paper: https://t.co/xqXtpjkYnK
💻 Code: https://t.co/ScMjVfBJvm

[Antonia Panescu @AF_Panescu]

Presented this work at #ICML2026 @genbio_workshop !

We introduce an order-agnostic approach to RNA inverse design. The result is more diverse, higher-confidence designs with higher solve rates while requiring fewer samples than standard best-of-N methods.

[Antonia Panescu @AF_Panescu]

GitHub: https://t.co/aJhiI94uLt
Poster: https://t.co/hlr3iLg1TR

[Antonia Panescu @AF_Panescu]

Had a great time attending ChemAI NYC 2026, presenting #CatalystBusters

If you’re looking for a physics-based, deterministic benchmark for your ML-generated enzyme sequences, consider using this!

[Antonia Panescu @AF_Panescu]

Had a great time contributing to this collaborative effort across biomedical domains!

A key question we asked was: can AI agents tell when the available data is sufficient to support a reliable conclusion? An important step toward trustworthy AI-driven scientific discovery 🤖🧬

[Tianyu Liu @meSuper8]

1/ 🤖Can agents solve problems in science? Most agent benchmarks test math/coding or reduce research to Q&A. Neither captures real research: multi-step workflows, messy data, tool use, knowing when a task is even feasible. So we built SciAgentArena: 200 tasks, 6 domains.

[Antonia Panescu @AF_Panescu]

If you are in the Bay Area, working on AI for Science, or attending those meetings, I would love to connect!

[Antonia Panescu @AF_Panescu]

A Lab with a View

Excited to spend my summer at the @BerkeleyLab in California, extending our previous work on Zatom-1!

Check out the paper here: https://t.co/QH6T1HYHYh

[Antonia Panescu @AF_Panescu]

This summer, I’ll also be at ChemAI NYC 2026 presenting CatalystBusters, a physics-based filter for triaging enzyme variants before synthesis, and at @icmlconf in Seoul, South Korea, where I will share some recent methodological work for RNA design.

[Alex Morehead (何聪) @MoreheadAlex]

Introducing Zatom-1, the first end-to-end, fully open-source foundation model for 3D chemistry! This was a great collaborative effort with many brilliant scientists. I'm grateful to have played a small part.

Paper: https://t.co/QXRCwnCFN8
Code: https://t.co/OC4JLhwsiR