ALS Research Forum

An open-access resource helping scientists to accelerate ALS drug discovery by fostering collaboration, reporting the latest news & sharing research tools.

[ALS Research Forum @ALSResForum]

Could a cancer drug targeting PARPs be repurposed as a treatment for #ALS #MND? A growing number of studies @PennMedicine suggest its a possibility. https://t.co/lsAUXXmWqY @LeeanneMcgurk @ShorterLab

[ALS Research Forum @ALSResForum]

#ICYMI Multiple therapies may be needed to treat #ALS #MND according to a new study https://t.co/dBMiRalF55 #MuSK #NMJ

[ALS Research Forum @ALSResForum]

Could a new technique help sort out the role of microglia in neurodegenerative diseases including #ALS #MND? https://t.co/fH3UPNc1cX

[ALS Research Forum @ALSResForum]

Looking to learn more about #ALS #MND but do not have access to a science or medical library? Check out our updated list of open-access reviews of the disease https://t.co/hqLhXqazBJ

[ALS Research Forum @ALSResForum]

Could disease heterogeneity be due to the "shapeshifting" nature of #TDP-43 pathology? A new #FTD study @NatureNeuro suggests its a possibility. https://t.co/fJxcSB2rQS #ALS #MND

[ALS Research Forum @ALSResForum]

Looking to present your latest findings in #ALS #MND at an upcoming scientific conference? Check out our 2019 meeting calendar! https://t.co/VM3Zse7q5E #ALS #MND

[ALS Research Forum @ALSResForum]

Are you aiming to facilitate clinical testing of potential #ALS #MND therapies by developing strategies to reduce disease heterogeneity? Check out this upcoming funding call @JPNDeurope to support your research https://t.co/BtYyqmIacI via @The_MRC

[ALS Research Forum @ALSResForum]

Could an emerging test help detect and monitor cognitive decline in neurodegenerative diseases? A new study @JAMANeuro suggests that its a possibility https://t.co/qTj2EgEa8t #FTD #ALS

[ALS Research Forum @ALSResForum]

Researchers @MGHNeurology detect glial activation in the spinal cord in addition to the brain in people with #ALS, a key step in developing an imaging-based tool to help evaluate potential immunotherapies in #clinicaltrials #alssymp

[Sheena Chew, MD @sheenachew]

Dr Suma Babu, showing us how it's done. Fantastic talk on spinal cord PET imaging biomarkers in #ALS. #alssymp @MGHNeurology @MeritCudkowicz @AtassiNazem

[ALS Research Forum @ALSResForum]

Learn more about this emerging adaptive #clinicaltrial design by checking out this article in @JAMA_current https://t.co/i895s3s3qo #ALS #alssymp

[Sabrina Paganoni, MD, PhD @PaganoniMDPhD]

Excellent session on #ALS #MND #clinicaltrials today #alssymp moderated by @MeritCudkowicz @LeonardvandBerg -learning from #oncology re: platform trials. Time to bring about a paradigm shift in ALS trials to make the drug development process faster and more efficient

[ALS Research Forum @ALSResForum]

Wondering how genotyping might help facilitate testing of potential therapies for #ALS #MND in the clinic? Check out this article from our archives https://t.co/bLqimD6B5S #UNC13A #C21 #alssymp

[ALS Research Forum @ALSResForum]

#ICYMI A new antibody aims to tackle #C9orf72 #ALS #MND by reducing levels of the dipeptide repeat protein poly-GA https://t.co/IG2el8xHsE #SfN18

[ALS Research Forum @ALSResForum]

MT @Dr_SharonB #DidYouKnow iPSC lines derived from patients with #ALS and #FTD are now available at @EBiSC_cells @ECACC? https://t.co/AGWf8yYqH2 #alssymp #3A

[ALS Research Forum @ALSResForum]

Learn more about emerging "organ on chip" models that aim to facilitate the development of treatments for neurodegenerative diseases including #ALS by optimizing their ability to enter the CNS https://t.co/sUSs8IeKlW #alssymp #C4

[ALS Research Forum @ALSResForum]

Wondering how changes in the gut could contribute to neurodegenerative diseases including #ALS? Check out this article from our archives https://t.co/hhR8IqAYgn #microbiome #C2 #alssymp

[ALS Research Forum @ALSResForum]

#ICYMI A new partnership sets the stage for clinical testing of the RIPK1 inhibitor #DNL747 in #ALS #MND https://t.co/1h8zdY0poJ @sanofi #necroptosis

[ALS Research Forum @ALSResForum]

Last chance to apply for a research grant @FondationLatran to fund your studies in #ALS #MND Abstracts due: December 6. https://t.co/829MrwF7Vt

[ALS Research Forum @ALSResForum]

#ICYMI A new pig model may help scientists to further evaluate potential therapies for #ALS #MND, particularly gene therapies. https://t.co/t476CtRtvo

[ALS Research Forum @ALSResForum]

Missed the first day of the #stemcell @CellSymposia in Los Angeles, California yesterday? Check out this article from our archives https://t.co/2taojssWyL #ALS #MND

[ALS Research Forum @ALSResForum]

Researchers debate a new strategy to tackle #ALS #MND targeting TDP-43 pathology at the 5th RNA Metabolism in Neurological Disease Conference in San Diego https://t.co/vY1dkZgHyo #stathmin2 #ASO #SfN18