Advances in Reproduction

Science & Technology Advances in Human Reproduction. #Reproduction #Science #Technology #Research #News

[Advances in Reproduction @AdvReproduction]

Both insufficient and excessive sleep are associated with accelerated aging in nearly every organ system. @Nature

[Science News @SciencNews]

Both short sleep (fewer than 6 hours) and long sleep (greater than 8 hours) correlate with faster biological aging. @Nature

[Nutrition Science @NutrioSci]

The Innovation Nutrition: An international journal of nutrition science

Open Access
https://t.co/oERdu3HnfN

[Nutrition Science @NutrioSci]

INAUGURATION  
The Innovation Nutrition: An international journal of nutrition science

Open Access
https://t.co/r0o0BB34ld

[Nutrition Science @NutrioSci]

Revisiting computational immunogenicity prediction for novel food ingredients

Open Access
https://t.co/gvMiJtIit0

[Nutrition Science @NutrioSci]

The challenge of weight management: Looking beyond short-term solutions

Open Access
https://t.co/PLw4C145jv

[Science News @SciencNews]

Time-restricted feeding extends healthspan in both sexes and lifespan in male @NatureAging

[Top Science @isciverse]

Why we need a good mood before bed

[Top Biomedical Science @imedverse]

Tumor metabolism at the center of the cancer hallmarks. #ASCO26

[Top Science @isciverse]

Tumor Metabolism: The Central Integrating Node of the 2026 Cancer Hallmarks

Open Access
https://t.co/9S0puMINir

In January 2026, Douglas Hanahan updated the "Cancer Hallmarks" framework. Our recent commentary in The Innovation Nutrition argues that tumor metabolism is no longer just a classic hallmark, but the "universal language" linking all dimensions of cancer biology. 

By positioning metabolic reprogramming at the center, we bridge FOUR critical dimensions: 
1. Core Hallmarks: Metabolism fuels proliferation and facilitates immune evasion via lactate-mediated acidification. 
2. Enabling Characteristics: It acts as a master conductor of epigenetic changes and is the "behind-the-scenes driver" of phenotypic plasticity. 
3. Microenvironmental Cells: The TME functions as a metabolic ecosystem where cancer cells and stromal cells (like CAFs) engage in "metabolic collaboration". 
4. Systemic Interactions: We highlight the emerging roles of neural regulation, the gut microbiome, and systemic conditions like cachexia in tumor progression. 

This multidimensional perspective provides a theoretical foundation for "Hallmark-guided personalized therapy".

By co-targeting metabolic nodes alongside other hallmarks, we can overcome therapy resistance and move toward true precision oncology.

#Cancer #CancerResearch #metabolism #Hallmark #Science #ASCO26 #TumorEnvironment #metastasis #news #TME #oncology #CAFs

[Top Biomedical Science @imedverse]

@OncoAlert ZEGFROVY® (sunvozertinib) monotherapy demonstrated superior anti-tumor efficacy, compared to platinum-doublet chemotherapy, in untreated NSCLC patients with EGFR exon 20 insertion mutations (exon20ins).

[Top Science @isciverse]

Presented at #ASCO26:

In NSCLC with 𝘌𝘎𝘍𝘙 exon 20 insertions, first-line sunvozertinib led to longer progression-free survival than chemotherapy. The most common adverse events of grade 3 or higher were elevated creatine kinase, diarrhea, and anemia.

[Nutrition Science @NutrioSci]

The efficacy of sunvozertinib was superior to that of chemotherapy as first-line treatment for advanced NSCLC with EGFR exon 20 insertions. @NEJM #ASCO26

[Dizal Pharmaceutical @Dizal_Global]

Phase 3 WU-KONG28 results for ZEGFROVY® demonstrate superior efficacy versus platinum-doublet chemotherapy in first-line EGFR exon20ins NSCLC.
Featured as an #ASCO26 LBA and published in The NEJM.
https://t.co/88SW5mbECP
#NSCLC #Oncology #EGFR #TKI #Exon20ins #LungCancer

[Nutrition Science @NutrioSci]

Economic evaluation of pediatric clinical nutrition intervention: A real-world study from the national children's medical center

Open Access
https://t.co/SUa0cSDFYT

[Top Biomedical Science @imedverse]

Dizal Announces Phase 3 WU-KONG28 Results:

ZEGFROVY®(Sunvozertinib) Outperforms Platinum-Doublet Chemotherapy in First-Line EGFR Exon 20 Insertion Mutation-Positive Non-Small Cell Lung Cancer. @NEJM

#ASCO26 #Oncology #EGFR #Cancer #LungCancer #NSCLC

[Science News @SciencNews]

In 1L EGFR exon20ins #NSCLC, oral sunvozertinib showed: @NEJM #ASCO26

PFS 10.3 vs 7.5 mos
HR 0.65
12-month PFS: 46.1% vs 26.7%
ORR 58.9% vs 31.1%

[Top Science @isciverse]

The 2025–2030 Dietary Guidelines for Americans — Progress, Pitfalls, and the Path Forward

The Innovation Nutrition
https://t.co/LTRFyQFle3

NEJM
https://t.co/Rnlck6edEE

[Top Biomedical Science @imedverse]

Overview of nutritional epidemiology, pathophysiology, guideline status, dietary risk and interventions for common dermatological conditions.

[Top Biomedical Science @imedverse]

Very large rewards markedly accelerated learning across tasks.

[Science News @SciencNews]

The role of AI in shaping future functional foods: Targeted delivery, biosynthesis, and personalized nutrition

[Nutrition Science @NutrioSci]

Neurotrophins not only support neuronal growth, development and function, but also play key roles in sensing nutritional status and regulating energy metabolism