The Agami Lab

[Elizabeth McKenna @ElizSMcKenna]

The new @CancerGrand Challenges teams have just been announced! Read about the teams tackling cancer avoidance, mechanisms driving mutational signatures, the dark proteome, cancer neuroscience, and rewiring cancer cells now in @CD_AACR: https://t.co/1TFqXBOGJR

[CRUK Cambridge Institute @CRUK_CI]

Team ILLUMINE, featuring our Hannon Group, will receive up to $25m over five years to take on the challenge of the dark proteome as part of Cancer Grand Challenges.

Full story: https://t.co/LI8rlN9uG4

[Champagne @Jchmpg]

We are hiring! Come and work with us from aberrant mRNA translation to innovative treatment opportunities. #agamilab #Bioinformatics #NKI https://t.co/1gBXwmaKXX

[Immunity @ImmunityCP]

Online now: Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation https://t.co/q3FDZsno9R

[The Agami Lab @AgamiLab]

Please have a look to our new publication in Immunity. https://t.co/i4sNOpBN4l (@ImmunityCP )!

[The Agami Lab @AgamiLab]

It has been a long journey since we first uncovered defective translation in cancer upon amino acid shortage in 2019 and today where we have been finally able to target cancer cells by adoptive T cell therapy against those aberrant peptides.

[The Agami Lab @AgamiLab]

Hopefully more T cell Receptor will be identified and more clinical applications will follow. A big thanks to the all Agami Lab and to our collaborators and fundings that have been essential to achieve this work. @JOlweus @oncodeinstitute @NKI_nl

[The Agami Lab @AgamiLab]

We are happy to announce that our group is among the three groups from the @NKI_nl that will receive the prestigious @ERC_Research Advanced Grant! This grant will support our goal of detecting and exploiting changes in the protein landscape of cancer.
➡️ https://t.co/0FeSgdcUdM

[The Agami Lab @AgamiLab]

We are thrilled to enounce the selection of our principle investigator Reuven Agami as a new member of @_knaw for his "series of highly original and high-impact discoveries"!

https://t.co/b77Hke9tuB

[The Agami Lab @AgamiLab]

Congratulations to @abhipataskar42 for being awarded the highly prestigious annual AvL prize for the most talented young researcher of the NKI. We are all very proud👏

[The Agami Lab @AgamiLab]

We are excited to share our recent review published fresh in Molecular Cell. It highlights recent advance on various protein diversification events by mRNA translation in cancer. #cancer #molecularcell #AcademicTwitter #mRNAtranslation #Cell

https://t.co/nUG6Nr2UvI

[The Agami Lab @AgamiLab]

A great Research Highlight by @lisa_heinke on our recent publication.

[Yuval Malka @YuvalMalka17]

How well do we understand the complexity of the transcriptome? in our new study (@AgamiLab, @alkan_ferhat, @liamfaller, and more), we uncover an unexpected function of cleavage and polyadenylation, which generates thousands of novel uncapped mRNA isoforms!
https://t.co/Hyn2NO8gr0

[The Agami Lab @AgamiLab]

We are looking for a talented Postdoc fellow to investigate "sloppiness" in mRNA translation in cancer. More details are below. #academicjobs #postdoc #CancerResearch #sciencejobs

[The Agami Lab @AgamiLab]

@abhipataskar42 @Jchmpg @JOlweus @BarbMarte @michal_bassani We also thank Pavel Baranov and John Atkins for their excellent news and views article, which can be read here; https://t.co/MyOYRKE3Mq

[The Agami Lab @AgamiLab]

We are very happy to share our recent paper published in Nature. We show that IFN-signaling associated Trp depletion leads to a new class of antigens, i.e Substitutants. Thank you @abhipataskar42 @Jchmpg @JOlweus @BarbMarte @michal_bassani and others.

[nature @Nature]

Nature research paper: Tryptophan depletion results in tryptophan-to-phenylalanine substitutants https://t.co/9kf2JfownK

[The Agami Lab @AgamiLab]

We have a postdoc position in bioinformatics at our group at NKI, Amsterdam. Please have a look for more details #nki #oncology #Bioinformatics

https://t.co/HHh5yrwOVf

[Rene Medema @MedemaRene]

#LIDLbyLIDL: ⁦@LidlNederland⁩ is making a statement, I suggest we all follow; they are the only supermarket I will shop at. https://t.co/mmrUZkxisT

[Lior Steinberg @LiorSteinberg]

Lidl, one of the largest supermarkets chains in the Netherlands, stops selling cigarettes and tobacco.
Good move by the German chain.

https://t.co/gawL9svJ8k

[Molecular Cell @MolecularCell]

Online Now: Oncogene-dependent sloppiness in mRNA translation https://t.co/ncEaWJUIwO