Alberto Zanella

[Intensive Care Medicine @yourICM]

Relevant parameters during #ICU stay & outcome in #COVID19
➡️1260 critically ill pts
➡️24 🇮🇹ICUs
➡️79% IMV
➡️34% mortality
Temporal trends of DP, respiratory compliance, creatinine, CRP, ferritin better predict mortality vs single daily values #COVIDFOAM
🔗https://t.co/niVxpFTre8

[Maurizio Cecconi @DrMCecconi]

1/5 The tension between scare mongers and deniers shows that we are not very good in explaining uncertainty and the balance between risk of harm and benefit to people. Most events in human life and medicine do not occur with 100% certainty.

[Maurizio Cecconi @DrMCecconi]

COVID19 is still real. We need everyone's help to keep schools, economies and healthcare systems going. Let's wear a mask, respect social distancing and hand washing rules, by doing so we can help our societies to run as normal as they can. We owe it to us and to our kids'future

[M Velia Antonini @FOAMecmo]

Fasibility, safety, effect on lung mechanics/oxygenation of proning on #ECMO, study (6 italian #ECLS centers/240 pts):
PP improved oxygenation, reduced intrapulmonary shunt, associated w significant reduction of H mortality
Minor complications in 6% of PP https://t.co/iaHoBWZfrN

[Sam Ghali, M.D. @EM_RESUS]

Watch this AMAZING real-time MRI showing what happens to the airway with various anatomical head and neck positions.

This is exactly why basic airway maneuvers save lives!

#FOAMed

[Massimiliano Greco @MGrecoMD]

[Thread] Come varia il tasso di ricovero per #Covid_19 nel corso dei mesi?
Questo grafico identifica 3 momenti distinti:
a. una fase iniziale, con percentuali di ricovero molto elevate dovute all'assenza di tamponi (denominatore "erroneamente" basso)
b. una seconda fase, dove [1/

[Our World in Data @OurWorldInData]

Our work on the COVID-19 pandemic [https://t.co/bp2y7cHaIf] now includes regularly updated data on excess mortality.
For many more countries than these three.

[the direct link to this chart is https://t.co/fNdfqpbgqt]

[Maurizio Cecconi @DrMCecconi]

Still wondering if COVID19 ARDS is something else? It is ARDS, with a range of features. Our latest collaborative paper from Italy: Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study https://t.co/i0HNEu6dFW

[Stefano Nava @StefanoNava5]

The first paper about the potential role of extracorporeal CO2 removal in stablr hypercapnic patients. In other words, the concept of CO2 dialysis.

[Massimiliano Greco @MGrecoMD]

Dati sui pazienti ricoverati in #terapiaintensiva per #COVID19, in Germania, Lombardia, USA:
-Nessuna patologia pregressa
Ger 22%, Lom 36%, USA 21.5%

-Piu' giovani di 60 anni
Ger 25%, Lom 25%, USA 44%

-Mortalità totale
Ger 53%, Lom 53%, USA 35.4%.
#covid, #COVIDー19, Fonti qui:

[Maurizio Cecconi @DrMCecconi]

Wondering about Risk Factors Associated With Hospital Mortality Among IMV Patients With COVID-19? Read our latest paper on nearly 4000 ICU pts @JAMAInternalMed @JAMA_current https://t.co/4rytIydh50

[Massimiliano Greco @MGrecoMD]

We analyzed characteristics and outcomes of a very large cohort of #COVID19 #ICU patients from Lombardy epidemic, with a median observation time of 70 days. The article was published today in JAMA Intern Med #coronavirus

[JAMA Internal Medicine @JAMAInternalMed]

In this retrospective cohort study of critically ill patients admitted to ICUs in #Lombardy, Italy, with laboratory-confirmed #COVID19, most patients required IMV. The mortality rate and absolute mortality were high https://t.co/XYNHSVBSvR #Coronavirus

[Max Roser @MaxCRoser]

Different German cities made masks mandatory at different points in time. This study uses a synthetic control methodology and finds that requiring face masks to be worn decreased the growth rate of COVID-19 cases by about 40% in Germany. https://t.co/swcajpKnLe

[Max Roser @MaxCRoser]

Only if we end the pandemic everywhere can we end the pandemic anywhere.

And globally we are very much not bending the curve. A record 188,633 cases were reported in the last 24 hours.

> https://t.co/8HhFFxXTAS

[Giacomo Bellani @GicoBellani]

In this paper on @LancetRespirMed we report our (@unimib and @Asst_Monza) findings on safety and feasibility of prone position in awake, spontaneusly breathing #COVID19 patients. Thanks @laveenamunshi @FralickMike and @efan75 for a GREAT editorial
https://t.co/yYAOmFSVIZ

[María Trapero @TraperoM]

Dr Massimo Carillo talking about Donation and transplant activity during #COVID19 pandemia in #Italy.
@ESOTtransplant @HepatologAs @SETHepatico @SETrasplante

[Marco Piani 🇮🇹🇨🇦 @Marco_Piani]

#COVID19 Worldwide: Timelines of deaths for countries w/ more than 300 deaths, with classification by region. Countries are ordered by date of maximum. Countries at the top are experiencing a surge, presently mostly in Asia, Africa, and South America.

Data: @OurWorldInData

[Marco Piani 🇮🇹🇨🇦 @Marco_Piani]

#COVID19 Worldwide: Total and daily deaths, with timelines and trajectories

Trajectories plotted with two thresholds, so to be able to better tell apart countries at a later stage of the pandemic.

Sweden has seen a recent rise in daily deaths. Brazil and Chile still growing.

[Nature Portfolio @NaturePortfolio]

A Nature paper reports that the early detection and isolation of #COVID19 cases in China prevented more infections than travel restrictions and contact reductions, but combined non-pharmaceutical interventions achieved the strongest and most rapid effect. https://t.co/naFIm7wgw4