Alessandro Di Gioia

Scientist, interested in human genetics, and former co-president of Boston Children’s Hospital now @RegeneronDNA. Ideas and thoughts are mine. He, his.

[Jack Kosmicki @jakphd]

😮‍💨Phew - it only took 2 years but our #GWAS of influenza (40k cases, 1.31M controls) is finally out in @NatureGenet.

https://t.co/sRFiqgpyLY

[Alessandro Di Gioia @AleXDiGiOX]

@giac_madd @Nature Amazing work Giacomo! Congratulations!

[Alessandro Di Gioia @AleXDiGiOX]

@helenxhou Cool tool! It might be interesting to test this system with the Gata2 cRE1 dup mice from Engle lab https://t.co/OtYF6pTfOi @ElizabethcEngle @Engle_Lab

[Max Tischfield @tischfield]

Interested in studying neuropsychiatric disorders and/or meningeal lymphatic biology? Please see the notice below for exciting opportunities in the lab! Previous experience with patch clamp physiology and optogenetics is a big plus. Please retweet and share with your network.🙏

[Hao Yin @HaoYin20]

Using Genomics to Identify Novel Therapeutic Targets for Aortic Disease
#AortaEd

A very well-composed review with clearcut descriptions of methodological development & conceptual pipeline for #ThoracicAorticDisease

Genetics+
#MachineLearning with Population-level Phenotyped Biobank😎
Perturb-seq
Single-cell omics
Target Prioritization🤓

Also an important update of aorta/#SmoothMuscleCell papers🙌

Avanthi Raghavan @patrick_ellinor @jpirruccello @MarkELindsay @atvbahajournals 2024
https://t.co/Yw8zkLLJwj

[Alessandro Di Gioia @AleXDiGiOX]

@michaelkosicki Thanks Michael! Your support was fundamental to solve this complex story!

[Alessandro Di Gioia @AleXDiGiOX]

@doctorveera @BostonChildrens @FMKirbyNeuro @WiscPediatrics Thanks Veera!

[Alessandro Di Gioia @AleXDiGiOX]

Excited to share our new paper from the Engle lab and collaborators.

[Nature Genetics @NatureGenet]

🚀 PUBLISHED @NatureGenet
📰 Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant hereditary congenital facial paresis
🧑‍🤝‍🧑 Elizabeth C. Engle, Alan P. Tenney, Silvio Alessandro Di Gioia, Bryn D. Webb and team
👇🏼
https://t.co/NAITc1LhyY

[Alessandro Di Gioia @AleXDiGiOX]

@BostonChildrens ,@FMKirbyNeuro ,@WiscPediatrics #Genetics, #RareDiseases

[Alessandro Di Gioia @AleXDiGiOX]

and finally a very big thanks to the participating families and their relatives. Without their engagement this would not have been possible. We really hope that one day this discover will bring to a cure for HCFP. @MoebiusSyndrome ,@Solve_RD, @NatureGenet ,@genome_gov