Alex Iskold | 2048.vc

Pre-seed and Seed VC @2048vc | | Coach @HarvardHBS | Blog | Systems Thinker | Red Rising and other Sci-Fi fan

[Alex Iskold | 2048.vc @alexiskold]

I am thrilled to share that we raised an oversubscribed $82M Fund III to lead pre-seed and seed rounds in Vertical AI, Deep Tech, Healthcare and Biotech startups in NYC and Boston.

To be exact, we raised $82,048,000 - a number that felt on-brand for a nerdy firm like ours that loves riddles, the future, Morse code, and Easter eggs.

We are immensely grateful to our LPs for their ongoing belief in our strategy and approach. We are equally grateful to the founders who have chosen to partner with us.

Here is 2048 Ventures Ventures Fund III in a nutshell:

- We back exceptional, ultra-competitive, visionary founders.

- We lead pre-seed and seed rounds with $500K - $3M checks.

- We invest in Vertical AI, Deep Tech, Healthcare and Biotech.

- We invest primarily in NYC and Boston.

- We seek businesses with strong data moats.

Read more about where we’re excited to invest:

https://t.co/upt3TpYLQt

If you are a builder and visionary looking for the highest conviction first-check investor, please reach out or re-share with your network!

[Fred Wilson @fredwilson]

The headline news is we have filled the gas tank again at USV and this tank is bigger. But scroll down to see the four areas we want to invest these funds into.

[USV @usv]

A thesis should take you somewhere new.

Ours began with the possibilities of the open internet. Today, it reaches across AI, energy, financial markets, and the physical world.

We’re evolving USV alongside it, with $900M in new funds to lead more rounds, back founders for longer, and support the scale of their ambitions.

@mignano on the next chapter of USV.

[Alex Iskold | 2048.vc @alexiskold]

@nickgrossman @usv Best of luck @nickgrossman - forever fans here @2048vc

[Nick Grossman @nickgrossman]

Just another day at the office @usv -- but excited to announce our latest set of funds: $900M in new capital to back startups from inception to momentum, at a moment when many large markets are about to be transformed.

[Rebecca Kaden @rebeccakaden]

Another chapter with the smartest, biggest thinking, and most fun team in the game to tackle idea-first investing in the greatest moment in history to do it.

More horsepower. Lots of hypotheses. World class founders knowing now is the time. LETS GO! Long @usv.

[Alex Iskold | 2048.vc @alexiskold]

Congratulations to our friends @usv a world class venture fund that is always an inspiration, never ending source of ideas, energy and rare kind of goodness

Best of luck - crush it!!!!

P.s @fredwilsonis is Messi of VC

[Michael Mignano @mignano]

https://t.co/9qDTCnoGaL

[Alex Iskold | 2048.vc @alexiskold]

@albertwenger @andrewparker @noahrshinn What do you think is the worse thing they can do with our info? Serious question

[Alex Iskold | 2048.vc @alexiskold]

@ColinMorelli Silence the robot!

[Mike Annunziata @nunzi46]

If you want to try a version of this product that’s already live on mobile and desktop, download @askloci

[Alex Iskold | 2048.vc @alexiskold]

@andrewparker @albertwenger @noahrshinn Yeah definitely. But I heard from someone very smart once about muscle memory :)

I can sense that some of it is building in how you organize things, etc.

But to be clear I agree with you, not insurmountably, just feels sticky and candidly feels really great. I love it.

[Alex Iskold | 2048.vc @alexiskold]

Good bye, AEO, it was nice to know you briefly.

https://t.co/rlo3kF29gl

[Jeff Weinstein @jeff_weinstein]

Introducing: Personal Agent Protocol (PAP)—an open standard for how personal agents interact with businesses.

@stripe is joining Meta, Sierra, Genesys, Instinct, Rocket, Shopify, and Walmart as founding members to design how the many agentic parties will play nicely together.

[Alex Iskold | 2048.vc @alexiskold]

@albertwenger @andrewparker @noahrshinn Agree. Will be hard for me to pop of Muse, as it is becoming a system of record and knowledge for both work and personal.

I mean I could but would need to be markedly better product.

[Alex Iskold | 2048.vc @alexiskold]

@albertwenger @markpinc @noahrshinn Gemini was good at the time when it came out. They are very slow to ship, agree. Not sure why. Maybe still playing wait and see, but Muse is cruising.

[Alex Iskold | 2048.vc @alexiskold]

@albertwenger @noahrshinn They must have this in house already.

[Darian Shirazi @darian314]

Zeroset is building temporal memory for agents! Excited to see them emerge from stealth with a $5.2M pre-seed led by us @GradientVC and @alexiskold - read more from @BusinessInsider: https://t.co/0thVmIWwMb

[William Zhang @wzhang]

We raised $5.2m at Zeroset to bridge the gap between frontier intelligence and the trajectories of enterprise workflows.

We believe in a future where companies own the models trained on their own traces.

If this interests you, join us at https://t.co/3kUym42R4s

Grateful to @darian314 @denise_teng25 @alexiskold @thisiszann for supporting our mission!

[Alex Iskold | 2048.vc @alexiskold]

Absolutely thrilled that @2048vc backed this super special team and work with @darian314 at @GradientVC

[Darian Shirazi @darian314]

Zeroset is building temporal memory for agents! Excited to see them emerge from stealth with a $5.2M pre-seed led by us @GradientVC and @alexiskold - read more from @BusinessInsider: https://t.co/0thVmIWwMb

[Alex Iskold | 2048.vc @alexiskold]

@thebowlboy @alexandr_wang Yes 👍

[Alex Iskold | 2048.vc @alexiskold]

@ares_mheinke User pays the agent, agent filters offers

[Alex Iskold | 2048.vc @alexiskold]

Email and text messages we receive today from advertisers are going to fade into the background.

The future is smartest brands building agents that promote things to our personal agents.

This is the future.

[Alex Iskold | 2048.vc @alexiskold]

Angles and micro VCs and multi stage funds and incredible concentration of talent. Insane gravity.

[Elizabeth Yin 💛 @dunkhippo33]

1/ Startup ecosystems everywhere are trying to copy Silicon Valley. But the secret isn't the weather or the schools. It's the angels. There are SO many of them. And what most people don't realize: a LOT of them are writing $1,000 checks. Read on >>