Alex Tokolyi

Medical genomics PhD student @SangerInstitute @Cambridge_Uni from 🇦🇺

[Alex Tokolyi @AlexTokolyi]

Very excited to share the first manuscript out of my PhD presenting our analysis into the genetic architecture of gene expression and splicing using blood RNA-seq of 4,732 blood donors from the INTERVAL study. (1/7) https://t.co/SkOUaRNfJK

[Claire Chewapreecha @chewapreecha]

Melioidosis kills 40% of cases, yet diagnosis remains a challenge. Many patients died before the arrival of a culture-confirmed diagnosis. With @PWongpalee and @TaoUttamapinant, we developed and validated a rapid test for melioidosis👇https://t.co/0FOMP7mQEj

[Alex Tokolyi @AlexTokolyi]

@chewapreecha @PhumBoonklang @ee_davenport Congratulations @PhumBoonklang !! Fantastic news

[Jonas Koeppel @JonasKoeppel]

What if we could inducibly create thousands of structural variants and ecDNAs in human cells and see which ones survive?

https://t.co/tbMsyfu8md

I’m excited to share our story on scrambling the human genome by combining prime editing, repetitive elements, and recombinases. A🧵

[Alex Tokolyi @AlexTokolyi]

I'd like to give a huge shout-out to @ee_davenport as well for being an amazing, passionate, & supportive supervisor throughout my PhD

[Emma Davenport @ee_davenport]

Congratulations Dr @AlexTokolyi! First PhD student of https://t.co/eNSDHzex1Q to complete (can you tell I'm just a little bit proud). Huge thanks to his examiners (@kauralasoo and John Whittaker) and our team and collaborators for all their support.

[Alex Tokolyi @AlexTokolyi]

@yang_i_li Summary statistics are now available on Zenodo: https://t.co/cd2QbwcPUD, and future links will be added to the portal: https://t.co/d2X9oK6mLK

[Alex Tokolyi @AlexTokolyi]

Very excited to share the first manuscript out of my PhD presenting our analysis into the genetic architecture of gene expression and splicing using blood RNA-seq of 4,732 blood donors from the INTERVAL study. (1/7) https://t.co/SkOUaRNfJK

[Alex Tokolyi @AlexTokolyi]

@yang_i_li I appreciate that! I was heavily inspired by your previous work for the splicing analyses

[Alex Tokolyi @AlexTokolyi]

I would like to give a huge thank-you to my supervisors and senior authors @ee_davenport, @minouye271 & @dirk_paul, and the lab at the @sangerinstitute for their support throughout this project

[Alex Tokolyi @AlexTokolyi]

All of these results are publicly available to browse and explore on our portal at: https://t.co/l3cAyGVbsG

[Thomas Vanderstichele @TVanderstichele]

Excited to share the first preprint of my PhD @sangerinstitute looking into the prevalence and genetic mechanisms of gene misexpression in 4,568 whole blood RNA-seq samples from the INTERVAL cohort. https://t.co/5Ia0Z1YVPR

[David A Knowles (@davidaknowles.bsky.social) @david_a_knowles]

Excited to share our work on targeting Cas13 to splice junctions for isoform-specific RNA knockdown. We learned a lot about the experimental design, assessment and downstream analysis of this approach. Phenomenal effort from all involved! https://t.co/6KhXamGXyJ

[Zoe Daniel (she/her) @zdaniel]

Today I lodged a Notice of Motion calling for a judicial inquiry into Media Diversity in Australia. (Seconded by @Mon4Kooyong)

[Dr. Scott C. Ritchie @sritchie73]

Pleased to announce our latest work is now live at Nature Metabolism (@natmetabolism), in which we show polygenic risk scores (PRS) can be used to identify novel and causal proteins underlying disease risk.

https://t.co/Re4PnSgwUy

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