Everything you want is on the other side of not giving a fuck, asking again, and taking another shot. Life gives you endless lottery tickets to try and you only need one win to change your life forever .
Let me explain what just happened.
Anthropic built a biology lab where Claude works alongside real scientists.
They told Claude to search a massive DNA database for interesting reverse transcriptases (enzymes that copy RNA into DNA). Then they let it run: ~950 Claude agents worked in parallel for 21 hours across 200,000+ enzymes.
One agent spotted a repeating DNA pattern next to an enzyme, the same kind of signature that originally led humans to discover CRISPR (the gene-editing tool that lets scientists precisely cut and edit DNA, now used in real medical treatments). It cross-checked the pattern against known systems, searched the literature, confirmed nobody had found it before, then wrote up a full scientific report like a human researcher would.
Anthropic scientists verified it in the lab. They named it ART. Its exact function is still unknown, but early signs suggest it may be programmable, similar to how CRISPR can be aimed at specific DNA.
Why it matters: finding tools like CRISPR used to take human experts months of manual searching. Here, AI did that work and found something real, at a speed no human team could match.
So don't misunderstand it as Claude curing cancer. Claude spotted something new in nature that humans missed.
Still crazy!
This is wild.
Claude just found something humans missed.
It spotted a hidden repeat pattern in raw bacteriophage DNA…
…and uncovered a previously unknown enzyme system in bacteriophages with CRISPR-like repeats. 🤯
950 agents. 21 hours. 210M tokens.
Last month I wrote about how we can build a positive and safe future for everyone: https://t.co/eoLGVY8yad
Every lab has the responsibility and incentive to move at the pace required to train its models safely, and the ability to take its own actions to ensure that happens.
The reality is:
- People won't want to use agents that are misaligned with them and that don't do what they ask, so labs have a strong natural incentive to make their models more aligned.
There is a lot of debate about slowing progress on capabilities until alignment catches up. My view is that trust and alignment are quickly becoming the most important capabilities that will differentiate agents and models. Any lab that doesn't focus on alignment will fall behind.
- Labs face significant liability if their models cause harm, so they have a strong incentive to prevent this as well.
Meta delayed shipping Muse for several months to focus on safety and security. We didn't call for everyone else to do this before we would. We just did it as part of our day-to-day work because it was clearly the right thing for people and for us. I'm proud of the security foundations we've built.
- Engaging independent evaluators and advisors is industry best practice. MSL already does this today in several areas because it helps produce better work. Other labs can just do this too. In general, it would be helpful for there to be a larger and more diverse ecosystem of evaluators.
- Committing the significant majority of compute towards serving people rather than racing towards recursive self-improvement is one of the best ways to ensure we develop this technology safely. Meta has made this commitment and other labs can do this as well.
I believe the key to building a positive future for everyone is maintaining the right balance of power. This is within our power to do.
Just f*cking do it.
Do it mad. Do it to the point of insanity. Do it with limited time. Do it with 3 kids. Do it at 80. Do it with sickness. Just fcking do it.
The world doesn't care about your potential. It only cares what you did.
Do it scared. Do it unprepared. Do it at 3 AM in bed. Do it while no one is watching. Do it while everyone is watching and calling you an idiot.
Algorithms make you stupid. Gatekeepers take all the profit. TV numbs your mind. Inaction is the kiss of death. You either do it and make memories, or die with fantasies that never came true.
Just f*cking do it. Do it without enough money. Do it on an 8 year old MacBook. Do it from your parent's basement. Do it while working a minimum wage job. Do it while everyone calls you a loser.
The competition has no idea what they're doing and they're lazy as f*ck. Do it for yourself. Do it for everyone who ever supported you.
99% of people do nothing with their life. You're different.
true neuroplasticity requires a massive ego. you have to be delusional enough to think you can master a complex system overnight, so you push past the exact wall of mental exhaustion where normal people quit.
I have a theory: if you put in 80%, you get 80% back. But if you put in 100%, you get 1,000% back. The last 20% is where the magic happens. Because almost nobody is mad enough to go all in. Only a perfect storm of delusion, obsession and a pinch of childhood trauma makes that extra 20% possible. It's the part where you keep going long after logic says retreat. Where your biggest weakness becomes your biggest strength: an inability to stop. Because at a certain point, success isn't about talent or luck. It's about who's willing to suffer for the longest. Pain is the filter. Few pass it.
Elon Musk came to the US with no money & graduated with over $100k in debt, despite scholarships & working 2 jobs while at school.
Today, he’s worth $1.1 trillion.
“If Elon Musk wasn’t a trillionaire, we could all afford healthcare.”
They fail to understand that Musk didn’t take his wealth from anyone.
It didn’t exist before he created it.
My favorite @elonmusk quote that I often send friends:
Do not fear losing. “You will lose,” Musk says. “It will hurt the first fifty times. When you get used to losing, you will play each game with less emotion.” You will be more fearless, take more risks.
>Be Elon
>Get bullied so badly as a kid that you end up in the hospital
>Escape into books
>Read more than 8hrs a day
>Teach yourself programming
>Sell a video game at 12
>Leave South Africa
>Sleep on couches
>Work odd jobs
>Get into America
>Build a startup
>Get fired from your own company
>Start over
>Build another company
>Merge it into PayPal
>Get removed as CEO
>Your company gets acquired
>Walk away with nearly $180 million
>Instead of retiring at 31, put almost all of it into three impossible ideas: Electric cars, Solar energy, Rockets
>People tell you you're insane
>Start a rocket company with no aerospace degree
>Learn rocket science from textbooks
>First rocket fails
>Second rocket fails
>Third rocket fails
>Divorce
>Public humiliation
>Cash running out
>One launch away from bankruptcy
>Launch anyway
>The fourth rocket reaches orbit
>NASA signs a contract
>Survive
>Tesla is weeks from collapse
>Save it at the last minute
>Get mocked for wanting reusable rockets.
>Land one.
>Then another.
>Then dozens.
>Turn science fiction into engineering
>Get mocked for betting on EVs
>Turn electric cars into status symbols
>Force the entire auto industry to follow
>Build the most valuable car company in history
>Launch astronauts into orbit
>Create a global satellite internet network.
>Buy Twitter
>Fire most of the staff
>Rename it X
>Walk into politics
>Risk your reputation
>Risk your companies
>Risk your fortune
>Become one of the most polarising people on Earth.
>Get attacked by the media, politicians, competitors, and activists
>Keep building anyway
>Become a TRILLIONAIRE
Key to winning:
Choose to be positive and grateful. Then, just keep at it. Time is the great compounder and will do the rest.
So many people just don’t have the discipline to stay positive and grateful. Then time compounds the bitterness instead.
Elon: Do things that make you want to live
“We’ve got to be excited about the future.
We have to do things that make us want to live.
It can’t always be about problems every day.
Do you really want to wake up every morning and everything is just a problem?
What inspires you?"
Source: @sageaurelius@elonmusk
@Tekeee your parents convinced one person to pay them for 40 years.
you need to convince 500 strangers once.
sounds harder. it's not. one "no" from a boss ends everything. one "no" from a stranger means nothing
> setting up OpenClaw was tough
> u were just getting used to it
> then Claude banned subscriptions
> u are not dumb & won't pay 20-30 times for API
> "time to look for Claude alternatives"
> and then u found this guide
> now u have an agent just as good
> and much more tokens