Alyson Fiorillo, PhD

Assistant Professor working towards therapeutics for Duchenne Muscular Dystrophy. Tweets are my own.

[Jason Sheltzer @JSheltzer]

Another scientist whose work initially didn't get the recognition that it deserved - Victor Ambros was denied tenure at Harvard, even after publishing the seminal work that resulted in him receiving the Nobel Prize today!

[Nicholas Johnson @nickjohnson30]

The Splice Index as a prognostic biomarker of strength and function in myotonic dystrophy type 1 https://t.co/HrKrFEve9Y

[Alyson Fiorillo, PhD @AlysonAFiorillo]

@YountLabOSU Corel Draw!

[Alyson Fiorillo, PhD @AlysonAFiorillo]

The follow up work related to this manuscript was recently funded by @MDAorg and we are looking for talented post-docs and lab staff to join our team! You can email me at [email protected]. (3/3)

[Alyson Fiorillo, PhD @AlysonAFiorillo]

Happy to share our latest article: Deletion of miR-146a enhances therapeutic protein restoration in model of dystrophin exon skipping: Molecular Therapy - Nucleic Acids https://t.co/I9S1nAHH4B. Congrats to first author and talented post-doc @nikkimmccormack! #DMD #microRNA (1/3)

[Alyson Fiorillo, PhD @AlysonAFiorillo]

Shout out to @TheHeierLab for another great collaboration. I also wanted to mention that my lab (@FiorilloLab) recently moved to @VCU to join the Center for Inherited Muscle Research led by @nickjohnson30. I am incredibly excited to be a part of this amazing group! (2/3)

[Alyson Fiorillo, PhD @AlysonAFiorillo]

@lvolpic We just got a quote from Leica to fix a cryostat that was no longer cooling. 25K.

[The Heier Laboratory @TheHeierLab]

Our new paper is published! Learning more about how steroids work in #Duchenne. Congrats to Trinitee on her first 1st author paper! @DMM_Journal has a nice interview with her, link to follow.
@MDAorg @ParentProjectMD @FiorilloLab @MYOTWlTTER #DMD

https://t.co/LQaffG2Kod

[Muscular Dystrophy Association @MDAorg]

#MDA celebrates the @US_FDA approval of AGAMREE® (vamorolone) to treat children and adolescents living with #Duchenne #MuscularDystrophy (#DMD). Learn more about this novel therapy, supported in part by MDA Venture Philanthropy: https://t.co/c9DfdgqPVW

[Children's National Hospital 🏥 @ChildrensNatl]

Positive news for boys with #Becker #MuscularDystrophy: Vamorolone improves disease progression with fewer side effects than current treatments. Read more from @TheHeierLab, @AlysonAFiorillo & the Center for Genetic Medicine Research. ⬇️ https://t.co/W17hjommbK

[Matthew S. Alexander @Matt_Muscle_Guy]

Congrats to @jyoti_k_jaiswal #JamesNovak & colleagues for their interesting new #CellDeathDiscovery paper: Altered muscle niche contributes to myogenic deficit in the D2-mdx model of severe DMD. https://t.co/ZhoGX6u2fn

[Alyson Fiorillo, PhD @AlysonAFiorillo]

Great team effort led by a very talented post-doc @nikkimmccormack. We find 1) vamorolone shows efficacy in our bmx mouse and 2) demonstrate that vamorolone reduces dystrophin-targeting miRNAs and increases dystrophin in skeletal muscle and heart!

[The Heier Laboratory @TheHeierLab]

Our new paper is out!
Vamorolone improves disease and increases dystrophin in our Becker muscular dystrophy model.
Now in clinical trials (NCT05166109)
#MuscularDystrophy #Becker #dystrophin
@FiorilloLab @MDAorg @ParentProjectMD @nih_nhlbi @iScience_CP
https://t.co/niTwAh3zyy

[Duchenne UK @DuchenneUK]

Our co-founder Alex Johnson and her son Jack appeared on @BBCBreakfast this morning to talk about Jack's journey down to London for the King's Coronation! 👑 @alljoinjack

[Amy Diehl, Ph.D. @amydiehl]

For male academics (who are 4x more likely to have a partner at home doing domestic care), the start of the COVID pandemic was a publishing boon. Of the 45 most prolific medical journal authors (60+ papers) during the 1st 18 months, just 5 were women.
https://t.co/5CkjJfocqn

[Alyson Fiorillo, PhD @AlysonAFiorillo]

@theFourier2k @MatthiasLambert @HogarthMarshall @MDAorg And @James Novak - we need to get him on muscletwitter!

[Monkol Lek @theFourier2k]

Yass! Operation warp speed for rare diseases proposed by Peter Marks (CBER, FDA) #mda2023 @NIHFunding @NIHDirector take note rare disease community are sick of being patient .. your inefficient funding cycles and processes don’t cut it in the information age!

[Frontiers in Genome Editing @FrontGenEditing]

New Research: Editorial: Genome and transcriptome editing to understand and treat neuromuscular diseases https://t.co/ZLiru6RMTW #GenomeEditing #CRISPR

[Prof. Toshi Yokota PhD FCAHS @MD_Canada Res Chair @ToshifumiYokota]

It was a pleasure working with co-editors @RikaMaruyama_E, @AlysonAFiorillo, @MacGyver0282, and Dongsheng Duan. Looking forward to more breakthroughs in the field! #ScienceAdvances #NeuroMuscularDiseases