Alyssa Inman

Tech-Startups-Soccer-Environment-Science-Nerd ....#ILLINI grad, MSci predictive analytics @NorthwesternU, data science & machine learning

[Zdenek Vrozina @ZdenekVrozina]

If you wear a Fitbit or a smartwatch, you may have noticed your HRV drop and your resting heart rate climb after COVID. Data from 1,475 people in the RECOVER cohort now confirm that pattern objectively - from passively collected sensor data🧵

[Harry Spoelstra @HarrySpoelstra]

Persistent Cerebral 18-FDG PET Changes in Patients With Long COVID Presenting With Fatigue and Post Exertional Malaise

🚨We already knew Long COVID brain damage could last 6 months.
Now this new PET scan study proves it’s still there at 2 YEARS and counting.
Hypometabolism hits the left sensorimotor cortex (movement + body sense), left superior parietal (spatial awareness + attention), and bilateral visual cortex (raw sight processing).
This is NOT just “tired.”
This is a broken sensory-motor command center.
Is this the start of a lifelong neurological disease?

➡️Mayo Clinic observational cohort study of 40 Long COVID patients (70% female, median age 53) from a specialized clinic who underwent brain 18F-FDG PET-CT scans 17–149 weeks (median 62 weeks) after SarsCoV2 infection,

➡️73% had predominant fatigue with post-exertional malaise (PEM),

➡️This group showed statistically significant cerebral hypometabolism vs. non-PEM patients in the left sensorimotor cortex (p=0.0253), left superior parietal cortex (p=0.0276), and bilateral primary visual cortex (p=0.0096 and 0.0016),

➡️Abnormalities persisted already up to ~2 years post-infection,

➡️Scans used pons-normalized Z-scores against age/gender-matched controls with common comorbidities included psychiatric, GI, and cardiovascular conditions,

➡️Caveat: No references to vaccination status and/or reinfections,

➡️Authors propose 18F-FDG PET-CT as a potential diagnostic and therapeutic biomarker for the fatigue/PEM phenotype of Long COVID.

‼️So, AGAIN, Long COVID fatigue and PEM have a demonstrable, persistent neurological signature! Cerebral hypometabolism, still detectable on PET scans up to two years later and hits the left sensorimotor cortex (movement + body sense), left superior parietal cortex (spatial awareness + attention), and bilateral primary visual cortex (raw sight processing).

This isn’t just “tired.”

It’s a broken sensory-motor command center.

😡Study proves LC is biologically real, not psychosomatic or any other stupid FND diagnosis.

Without urgent validation of this biomarker and targeted therapies, patients will continue to be dismissed despite objective brain damage!
#AvoidSars2 #AvoidReinfections #BrainDamage
https://t.co/OfoOlgDyt0

[Mike Hoerger, PhD MSCR MBA @michael_hoerger]

Is COVlD going away or...
Are we about to get slammed by the BA.3.2 variant?
🔥🔥🔥

[Zdenek Vrozina @ZdenekVrozina]

Reinfection during the Omicron era is associated with about twice the risk of a documented long COVID diagnosis in children. Online September 2025, print issue February 2026🧵

[Alyssa Inman @Alyssaeinman]

@hubermanlab That article tho…Looking at total number of prescriptions per year is misleading and vastly overstates the implied number of people on the drug. Each patient requires a new Rx every month. A rough estimate of total number of patients using is closer to:
41.4M/12 = 3.45M

[Alyssa Inman @Alyssaeinman]

@lisaderus @subaru_usa Omg Lisa- so glad you and baby are OK!! ❤️❤️

[Chris Murphy 🟧 @ChrisMurphyCT]

My kids don’t understand why I work on anything other than climate change.

Why does anything else matter if you don’t fix this, they wonder.

[AJ Leonardi, MBBS, PhD, MPH @fitterhappierAJ]

Watch this video.

What is happening here is that sars cov 2 is taking normal cells

And fusing them into zombified giant cells.

[Alyssa Inman @Alyssaeinman]

@gkbrauer I’m in!

[Alyssa Inman @Alyssaeinman]

@drewcoffman The Giver

[Dakota Smith @weatherdak]

Gut-wrenching imagery of California tonight.

Multiple, destructive wildfires exhibiting extreme behavior.

[National Geographic @NatGeo]

Although they're called natural disasters, only 10 to 15 percent of wildfires occur on their own in nature https://t.co/QCRiFa4PfO

[Caitlin Hudon @beeonaposy]

Ina tackles machine learning

[Abdu Sharkawy @SharkawyMD]

This is what #LongCovid is. "Fatigue. Lethargy. Heavy limbs.. could barely move... shortness of breath...bloating. Struggling just to get out of bed some days." An elite athlete missed his shot. Don't miss yours. #ThisIsOurShot
https://t.co/UaiRcIjfeE

[Eric Feigl-Ding @DrEricDing]

My god—over 25,000 drums of@toxic waste found dumped on the ocean floor off coast of California. The number of drums laced with the pesticide DDT far exceeded expectations. “It was hard to wrap my head around the density”. And they are likely leaking. 🧵
https://t.co/LgBBuF094o

[Atul Gawande @Atul_Gawande]

What a magnificent way to spend one’s 15 minute observation period. Thank you #YoYoMa.

[Peter Lee @peteratmsr]

Here @Microsoft @Health_IT the @AdaptiveBiotech folks challenged us to accelerate, dramatically, the work on T-cell based diagnostics in order to help the world respond to #COVID19. We said yes but honestly didn't know if it would be possible. But it was, and here it is.

[Moises Velasquez-Manoff @moisesvm]

My latest story in @NYTmag on #longcovid, the people whose symptoms persist long after the acute phase of covid19. As Anthony Fauci has noted, it's going to be a significant public health issue going forward. https://t.co/xMSogmfYFf

[Omar Jimenez @OmarJimenez]

I saw more arrests during protests in Minneapolis this summer than I have watching people storm the US Capitol.

[Prof. Akiko Iwasaki @VirusesImmunity]

People requested a more accessible version of the explainer of our study with @aaronmring on autoantibodies in #COVID19 disease. We are so fortunate to work with @YaleMed video production team to create this. Check it out! #scicomm

https://t.co/tW8scRngKp