Anatomic Incorporated

Not Your Average Neuron™

Rapid production of human induced pluripotent stem cell-derived nociceptors for research and therapeutic applications.

[Anatomic Incorporated @AnatomicTech]

Sometimes morphology tells the story before the data does.

High-purity RealDRG human iPSC-derived sensory neurons stained for ISL1 (white) and TUJ1 (red). This consistency helps make downstream assays more reproducible.

#painresearch #iPSC #neuroscience #drugdiscovery

[Anatomic Incorporated @AnatomicTech]

📰From the Field: Gene supplementation for LBSL

Annals of Neurology shows AAV9-DARS2 improves mitochondrial function and axonal growth in iPSC sensory neurons, with in vivo rescue

Anatomic Senso-DM™ enabled patient sensory neuron modeling

🔗https://t.co/yJSijiMVem

[Anatomic Incorporated @AnatomicTech]

New protocol 🚨 Co-culture RealDRG™ sensory neurons with RealDHN™ dorsal horn neurons on the eNUVIO OMEGA4 to model functional pain circuits and sensory–spinal connectivity.
Flexible workflow: use RealDRG™ alone or swap in your cell type of choice.
#NotYourAverageNeuron

[Anatomic Incorporated @AnatomicTech]

Last weekend, Team Anatomic joined #Walk4CMT Minneapolis 💙 Proud to support an important cause, raise awareness, and help fund progress toward a cure. Thanks to everyone who walked with us and @cmtausa for organizing!

[Anatomic Incorporated @AnatomicTech]

NEW Human Trigeminal Neurons for #MigraineResearch!
Phase-contrast images from our newest human iPSC-derived trigeminal neurons show high neuronal purity-no mitomycin C needed. Follow us for updates on functional characterization of migraine & pain targets #NotYourAverageNeuron

[Anatomic Incorporated @AnatomicTech]

🎥 A glimpse into our 7-day directed differentiation of human iPSC-derived dorsal horn neurons. Fast. Reproducible. Ready for pain pathway discovery.

#NotYourAverageNeuron #CompleteTheCircuit #neuroscience #drugdiscovery #iPSC #dorsalhorn #painresearch

[Anatomic Incorporated @AnatomicTech]

Motor neurons alone can't explain ALS or CMT. Schwann Cell Precursors reveal how disrupted glial-neuronal crosstalk drives disease. Co-cultures model early pathogenesis, glial dysfunction, and myelination defects more accurately

#CompleteTheCircuit #NotYourAverageNeuron

[Anatomic Incorporated @AnatomicTech]

Add These Publications to Your Reading List📚
Explore all publications featuring Anatomic’s products in one place-a fast way to find relevant assays & new applications
See how our models are advancing discovery: https://t.co/AQ0c7xXrqm

#CompleteTheCircuit #NotYourAverageNeuron

[Anatomic Incorporated @AnatomicTech]

The Kolber Lab at UTD has launched a core facility featuring a high-content screening assay for analgesic discovery using the Axion BioSystems Maestro Pro, now featured in their latest publication

Read the article here:
https://t.co/kEAHGnEwAf

[Anatomic Incorporated @AnatomicTech]

Team Anatomic hit the pavement together for the #Walk4CMT 💙 Grateful to be part of a community that's raising awareness, showing support, and walking toward a cure. Huge to @cmtausa for putting on a well organized and meaningful event!

[Anatomic Incorporated @AnatomicTech]

Keepin it local🤙🏼Attended the 3rd MN Organoid Symposium put on by the @umnmedschool & @MayoClinic earlier this week. Big shoutout to our Scitech intern Devanshi who gave her first poster presentation! Reach out to learn more about applications in this space➡️[email protected]

[Anatomic Incorporated @AnatomicTech]

🌉Vince will be speaking at the @AxionBioSystems World Tour: San Francisco User Group Meeting on April 17, 2025!
🎤“Completing the Circuit: Advanced hiPSC-Based Models of the Peripheral Nervous System for Disease Modeling and Drug Discovery"

🔗Register https://t.co/h9GEnkBxfZ

[Anatomic Incorporated @AnatomicTech]

💡 Enhance your research! Integrate Schwann cell precursors (SCPs) into your motor neuron (MNs) cultures

As SCPs mature, they migrate & align along axons, visualized using immunofluorescent staining—S100b/SOX10 (SCPs) & TUJ1 (MNs)

#CompleteTheCircuit #ALSResearch

[Anatomic Incorporated @AnatomicTech]

💎Check-out the purity💎 Images of RealDHN hiPSC-derived dorsal horn neuron cultures, generated without the need for genetic engineering or Mitomycin C treatment

Visit https://t.co/Kd309EtnQD for more info on the molecular and functional characterization of the neurons!

[Anatomic Incorporated @AnatomicTech]

Anatomic has been focused on developing CIPN-related assays for the last few years. The FDA’s new draft guidance underscores the need for better study designs and endpoints in CIPN research.

Read the full guidance below!
#CompleteTheCircuit #CIPNResearch

[Anatomic Incorporated @AnatomicTech]

💎Check-out the purity💎 Images of co-cultures of RealSCP, hiPSC-derived Schwann cell precursors, and RealDRG, hiPSC-derived sensory neurons, generated without the need for genetic engineering or Mitomycin C

#CompleteTheCircuit #NotYourAverageNeuron

[Anatomic Incorporated @AnatomicTech]

It’s always tough to pick favorites when there’s so much exciting data to explore! 🤩 We have compiled our favorite data from over the years onto a new page for your easy access

Check out our data highlights page at:
https://t.co/bwLpk7DhmH

[Anatomic Incorporated @AnatomicTech]

Harnessing a more physiological in vitro model for CIPN! Dr. Nanna Elman Andersen’s Ph.D. thesis explores chemotherapy-induced neurotoxicity using hiPSC-derived Schwann cells & sensory neurons, studying paclitaxel, vincristine & bortezomib

https://t.co/xZ5On5jV3y

[Anatomic Incorporated @AnatomicTech]

Science is serious stuff, but sometimes it can’t help but make you smile.

Especially when it smiles first 😁

[Anatomic Incorporated @AnatomicTech]

🧒🏻👧🏽👦🏼👩🏽‍🦱Multiple donors. Same process. Sensory neurons derived from hiPSC lines (both healthy and diseased) express key ion channel targets for pain - NaV1.7, NaV1.8, and TRPV1
#NotYourAverageNeuron #CompleteTheCircuit #DiseaseModeling #PainResearch