Delighted to share our latest, expertly led by @KatlynGabriel_ and @ChoahK:
FAF2 is a bifunctional regulator of peroxisomal homeostasis and saturated lipid responses
Impactful work with therapeutic potential by our @GrekaLab team at @broadinstitute!
https://t.co/2TIcDVjOpz
Research support for rare diseases, which cumulatively affect ~30 million Americans, is primarily derived from NIH.
Such work is exemplified by @AnnaGreka@broadinstitute in a new Ground Truths podcast.
Open-access, w/ transcript, full video, no ads
Flushing out misfolded uromodulin as a treatment concept for kidney proteinopathies: https://t.co/mjQjT7Zewm
ASCI member @AnnaGreka & team @harvardmed restored uromodulin localization in models of autosomal dominant tubulointerstitial kidney disease using a TMED-targeting small molecule.
Delighted to share our latest @GrekaLab story in collaboration with @WuLabHarvard on the molecular basis of TMED9 cargo receptor oligomerization and entrapment of misfolded cargo in the early secretory pathway. @broadinstitute@harvardmed@MassGenBrigham
https://t.co/2oJMjGdr1E
Studies in mice suggest that strategies to enhance kidney TREM2 high macrophages may provide therapeutic benefits for DKD #diabetes#kidneydisease@CellReports https://t.co/4hc6i189Wr
"The amazing thing about science is that if you follow your curiosity, it can lead you to untold scientific treasures" - @AnnaGreka
Watch Dr. Greka's TED Talk to learn more about her work and the impact it can have on millions of people globally.
https://t.co/5HzaieZPiH
"The amazing thing about science is that if you follow your curiosity, it can lead you to untold scientific treasures" - @AnnaGreka
Watch Dr. Greka's TED Talk to learn more about her work and the impact it can have on millions of people globally.
https://t.co/5HzaieZPiH
Congratulations @AnnaGreka on the fantastic @TEDTalks! Hear from Anna on "The world's rarest diseases — and how they impact everyone." https://t.co/jlshaACc6H @GrekaLab
Join us on Tuesday, July 18 for the inaugural Ladders to Cures Symposium focused on efforts to scale mechanisms-focused research in genetic diseases. This event is hybrid and open to all. Please visit https://t.co/OAAc8Rb9eP to register and see the agenda.
Our team is excited to invite you to the inaugural Ladders to Cures Symposium focused on efforts to scale mechanisms-focused research in genetic diseases. This hybrid event is July 18, 2023. Please visit https://t.co/ACmtAMSFvL to register and see the agenda. @broadinstitute
Congratulations to @HarvardMITmdphd student @JCoraorFried and mentor @AnnaGreka for Juli’s successful thesis defense entitled, “FALCON systematically interrogates FFA biology and identifies new mediators of lipotoxicity.” We are beyond proud! @grekalab@BBS_Harvard