Anto Merlotti

Immunology | Antigen Discovery | Cell Therapy | Immuno-Oncology

[Anto Merlotti @AntoMerlotti]

With great pleasure and happiness, I’m sharing our papers published in Science Immunology!
We find that non-canonical splice Junctions between Exons and Transposable elements (JETs) are a new source of recurrent and shared tumor-specific antigens. (Open thread)

[Science Immunology @SciImmunology]

Two studies involving patients and mouse models explore the immunogenic potential of tumor-specific antigens encoded by exon-transposable element splicing junctions in the realm of #cancer immunotherapy. @institut_curie

➡️ https://t.co/MM2d86AOa6
➡️ https://t.co/s0fqnpv1by

[Anto Merlotti @AntoMerlotti]

I’m very proud and excited to share our last work that @YagoArribas carried out at @institut_curie

It’s a privilege to work with such a brilliant scientist and a great friend. Thank you!

Thanks to Amigorena's team, collaborators and funding for their participation and support

[Yago Arribas @YagoArribas]

Not easy to describe the emotions of seeing our work published in @CellCellPress ! We explored how novel isoforms emerge during evolution through the exonization of Transposable Elements. Exonized TEs modify the functions and structures of host proteins.
https://t.co/s6nkORnGbE

[Yago Arribas @YagoArribas]

Not easy to describe the emotions of seeing our work published in @CellCellPress ! We explored how novel isoforms emerge during evolution through the exonization of Transposable Elements. Exonized TEs modify the functions and structures of host proteins.
https://t.co/s6nkORnGbE

[Fabricio Ballarini @FabBallarini]

Orgullo Nacional!!!

Así le comunicaban al matemático Argentino Luis Caffarelli que acababa de ganar el premio Abel (el equivalente al premio Nobel de las matemáticas).

Una felicidad enorme para la comunidad científica de nuestro país.

[Laurie Menger @LaurieMengerLab]

2 years funded Research Engineer Position (renewable) therapeutic T-cell engineering at Gustave Roussy (France)!

[Cancer Discovery @CD_AACR]

Cancer Discovery #ResearchWatch:
Noncanonical Splice Junctions Encode Immunogenic Tumor Neoantigens, summarizing the complementary papers by @MarianneBurbage, Ares Rocañín-Arjó, @AntoMerlotti, Benjamin Sadacca, @YagoArribas @JoshWaterfall @Sebasti92658716 @institut_curie @Inserm

[ACIR @ACIR_org]

Non-canonical splice junctions between exons and transposable elements (JETs) were recently found to be a source of tumor antigens in murine and patient samples https://t.co/888YfxjJ5L
@institut_curie @MarianneBurbage @Inserm @AntoMerlotti @YagoArribas @JoshWaterfall

[Science Immunology @SciImmunology]

While exploring how splicing junctions between exons and transposable elements contribute to tumor-specific antigens, scientists found that the histone methyltransferase Setdb1 epigenetically controls their expression in mice. @institut_curie

📄: https://t.co/AuNpn9KjNN

[Anto Merlotti @AntoMerlotti]

Take a look at this great opportunity in Legoux’s Lab ⬇️

[Legoux Lab @LabLegoux]

We are looking for a PhD candidate to explore MAIT cell development using new tools🐁. Starting date: next Fall ! More information and applications 👇

[Anto Merlotti @AntoMerlotti]

Big kudos to @AlexisFinkbein3 our cover designer, thanks for this illustration.

[Anto Merlotti @AntoMerlotti]

With great pleasure and happiness, I’m sharing our papers published in Science Immunology!
We find that non-canonical splice Junctions between Exons and Transposable elements (JETs) are a new source of recurrent and shared tumor-specific antigens. (Open thread)

[Science Immunology @SciImmunology]

Two studies involving patients and mouse models explore the immunogenic potential of tumor-specific antigens encoded by exon-transposable element splicing junctions in the realm of #cancer immunotherapy. @institut_curie

➡️ https://t.co/MM2d86AOa6
➡️ https://t.co/s0fqnpv1by

[Anto Merlotti @AntoMerlotti]

A big thanks to Sebastian Amigorena and @JoshWaterfall, to all co-authors for their participation and collaboration, to @institut_curie and @MnemoTx for supporting these projects!

[Anto Merlotti @AntoMerlotti]

It was a pleasure to participate in this great work from Sebastian Amigorena’s lab at @institut_curie Congrats to the first authors
@YagoArribas and PE Bonté and all the team C. Goudot @C_Alanio @EllaZ_InstCurie 👏🏽👏🏽👏🏽 #Immunology #cancer

[Yago Arribas @YagoArribas]

My first first author paper is out! :)

Single-cell RNA-seq-based proteogenomics identifies glioblastoma-specific transposable elements encoding HLA-I-presented peptides https://t.co/kwX6tKUzin

[Yago Arribas @YagoArribas]

My first first author paper is out! :)

Single-cell RNA-seq-based proteogenomics identifies glioblastoma-specific transposable elements encoding HLA-I-presented peptides https://t.co/kwX6tKUzin

[Anto Merlotti @AntoMerlotti]

@nachogudino_ Excelente

[Nacho Gudiño 🚀 @nachogudino_]

Hice la intro de Okupas al estilo Friends

[Alejandro Bercovich @aleberco]

Vacunas que llegaron hasta hoy a 🇦🇷
Total 36.291.730 dosis 🦟
💉11.868.830 Sputnik V 🇷🇺
💉 10.608.000 Sinopharm 🇨🇳
💉 580.000 AsZeneca-Covishield 🇮🇳
💉 1.944.000 AsZeneca vía COVAX 🌎
💉 7.790.900 AsZeneca hechas en Arg 🇦🇷 envasadas en Mex 🇲🇽
💉 3.500.000 Moderna donadas por 🇺🇸

[Concepcion Perre @MCPerre]

Se merecía un monumento

[Anto Merlotti @AntoMerlotti]

@malepichot Che se dieron cuenta que el short de Tomi es la bandera yanki, no? 🤦🏽‍♀️