With great pleasure and happiness, I’m sharing our papers published in Science Immunology!
We find that non-canonical splice Junctions between Exons and Transposable elements (JETs) are a new source of recurrent and shared tumor-specific antigens. (Open thread)
Two studies involving patients and mouse models explore the immunogenic potential of tumor-specific antigens encoded by exon-transposable element splicing junctions in the realm of #cancer immunotherapy. @institut_curie
➡️ https://t.co/MM2d86AOa6
➡️ https://t.co/s0fqnpv1by
I’m very proud and excited to share our last work that @YagoArribas carried out at @institut_curie
It’s a privilege to work with such a brilliant scientist and a great friend. Thank you!
Thanks to Amigorena's team, collaborators and funding for their participation and support
Not easy to describe the emotions of seeing our work published in @CellCellPress ! We explored how novel isoforms emerge during evolution through the exonization of Transposable Elements. Exonized TEs modify the functions and structures of host proteins.
https://t.co/s6nkORnGbE
Not easy to describe the emotions of seeing our work published in @CellCellPress ! We explored how novel isoforms emerge during evolution through the exonization of Transposable Elements. Exonized TEs modify the functions and structures of host proteins.
https://t.co/s6nkORnGbE
Orgullo Nacional!!!
Así le comunicaban al matemático Argentino Luis Caffarelli que acababa de ganar el premio Abel (el equivalente al premio Nobel de las matemáticas).
Una felicidad enorme para la comunidad científica de nuestro país.
Non-canonical splice junctions between exons and transposable elements (JETs) were recently found to be a source of tumor antigens in murine and patient samples https://t.co/888YfxjJ5L
@institut_curie @MarianneBurbage @Inserm@AntoMerlotti@YagoArribas @JoshWaterfall
While exploring how splicing junctions between exons and transposable elements contribute to tumor-specific antigens, scientists found that the histone methyltransferase Setdb1 epigenetically controls their expression in mice. @institut_curie
📄: https://t.co/AuNpn9KjNN
With great pleasure and happiness, I’m sharing our papers published in Science Immunology!
We find that non-canonical splice Junctions between Exons and Transposable elements (JETs) are a new source of recurrent and shared tumor-specific antigens. (Open thread)
Two studies involving patients and mouse models explore the immunogenic potential of tumor-specific antigens encoded by exon-transposable element splicing junctions in the realm of #cancer immunotherapy. @institut_curie
➡️ https://t.co/MM2d86AOa6
➡️ https://t.co/s0fqnpv1by
A big thanks to Sebastian Amigorena and @JoshWaterfall, to all co-authors for their participation and collaboration, to @institut_curie and @MnemoTx for supporting these projects!
My first first author paper is out! :)
Single-cell RNA-seq-based proteogenomics identifies glioblastoma-specific transposable elements encoding HLA-I-presented peptides https://t.co/kwX6tKUzin
My first first author paper is out! :)
Single-cell RNA-seq-based proteogenomics identifies glioblastoma-specific transposable elements encoding HLA-I-presented peptides https://t.co/kwX6tKUzin