Anup Jha

Graduate Student @ACTREC_TMC (Hemato-oncology, Hasan Lab).
Ocassionally a photographer, mainly a foodie, forever a SidHeart!💛

[Anup Jha @Anupjha59]

Thank you @CRI_ACTREC for supporting me, and @SyedKHasan1 Sir for the guidance.😁

[Cancer Research Institute - ACTREC @CRI_ACTREC]

Anup Jha, Dr. Syed Hasan's lab @ACTREC_TMC has been awarded the prestigious Fulbright Nehru Doctoral Research Fellowship (2026-27) for 9 months in the USA. His research would focus on understanding the mechanisms of therapy resistance in AML! @biopatrika

[Anup Jha @Anupjha59]

@AviJRFaspirant @CRI_ACTREC @ACTREC_TMC @biopatrika Thank you

[Anup Jha @Anupjha59]

@BA__khan @CRI_ACTREC @ACTREC_TMC @biopatrika Thank you

[Dr. S. Jaishankar @DrSJaishankar]

8,931 days and counting!

PM Shri @narendramodi has become 🇮🇳’s longest-serving head of government, surpassing former Sikkim CM Shri Pawan Kumar Chamling’s record of 8,930 days in public service.

His inspiring journey of Jan Seva, first as Gujarat CM and three times as the Prime Minister, reflects the immense public trust and enduring connect with the people of India.

#ViksitBharat
#PradhanSevakModi

[MV Chandrakanth @ChandrakanthMv]

Venetoclax is one of the most powerful drugs in CLL.
But rapid apoptosis can cause tumor lysis syndrome.
That’s why the famous ramp-up exists:
20 → 50 → 100 → 200 → 400 mg
Understanding the biology behind the dosing 👇
#MVOnco #CLL #Hematology

[William A. Wallace, Ph.D. @WilliamWallace]

Your mitochondria are not batteries, they’re chemical factories. And this is what they’re building....

This diagram looks complex because it is. Your mitochondria act like tiny biochemical control centers that influence how well you think, heal, detoxify, fight infection, and even age.

Here’s the simple version:

1️⃣ They don’t just make energy, they make the building blocks of life.

Mitochondria produce the raw materials your cells need for:

-DNA & RNA
-Brain chemicals
-Antioxidants
-Cell membranes
-Repair enzymes

When mitochondria slow down, everything from immunity to cognition takes a hit.

2️⃣ They run a huge “chemical circuit” that keeps your cells functioning.

This network ties together:

-Folate
-B-vitamins
-Methylation
-Detox pathways
-Glutathione production
-DNA synthesis

Mitochondria supply key molecules (like formate) that cells use to build DNA and regulate repair.
This affects growth, immunity, fertility, inflammation, and aging.

3️⃣ When mitochondria falter, the effects ripple everywhere.

You don’t just feel tired, you see:

-More inflammation
-Poor detoxification processes
-Slower healing
-Brain fog
-Hormone imbalance
-Faster aging

Because the upstream control system is failing.

4️⃣ The takeaway

Your mitochondria aren’t batteries.
They’re the operating system that keeps your cells alive, communicating, and repairing damage.

Support them… and you support everything your body is trying to do.

📄 Source: Cell (2024). Mitochondrial one-carbon metabolism and its role in cellular biosynthesis and signaling.

[ACS Journal Cancer @JournalCancer]

Newly published, #OpenAccess: In FLT3-TKD mutated acute myeloid leukemia, NPM1 co-mutation links to better survival. Patients without it face worse outcomes & may benefit from early stem cell transplant.

Read on: https://t.co/ViVy5E7acb

@OncoAlert @DrHKantarjian @Daver_Leukemia

[Madam Mitochondria @Madam_Mito]

https://t.co/1uBaVe0Zl2

Therapeutic Transplantation of Mitochondria and Extracellular Vesicles: Mechanistic Insights into mitochondria bioenergetics, redox signaling, and organelle dynamics in preclinical models.

[Sumeet Mirgh MD, DM @MirghSumeet]

Just published in @CancerMedicine
15 years of PBSC mobilization experience in Myeloma

Even in the CAR-T era, collecting sufficient PBSCs is crucial.

- GCSF+plerixafor comparable to chemo mobilization
- If prior RT (to hematopoietic sites - spine, pelvis), chemo-mobn is better

[The PhD Place @ThePhDPlace]

You will get through your PhD

[Gentle Man @Gentlenmasc]

8 Greatest Laws I know at 35, I wish I knew at 20:

– Thread –

1.

[AIIMS, New Delhi 🇮🇳 @aiims_newdelhi]

Cases of Acute Myeloid Leukaemia (AML) - a rare, fast-growing cancer of the blood and bone marrow - are rising in the 30-40 age group. Individuals previously exposed to radiation or chemotherapy may be at higher risk. A simple blood test can help detect AML early.

[Anup Jha @Anupjha59]

Happy to share the newly published review article from our lab, wherein we discuss about NRF2 regulated oxidative stress in cancer. Immensely thankful to all the collaborators and my guide @SyedKHasan1 Sir for giving me this wonderful opportunity.
Link:
https://t.co/g0JEQkcuJh

[All India Research Scholars Association @AIRSAIndia]

Appeal! To Hon'ble Prime Minister of India @narendramodi @CSIR_IND it's time to #RaiseTheAgeLimit #AIRSA is calling for a fair chance for researchers.The current 32-year cap for scientist positions is stifling talent. We need it raised to 40! @the_hindu
https://t.co/lnpUawuTkw

[Austin E. Y. T. Lefebvre @Austin_Lefebvre]

Do you LOVE organelles??
Well I am THRILLED to announce that Nellie has been published in @naturemethods!

Nellie a fully automated pipeline for organelle segmentation, tracking, and hierarchical feature extraction in 2D, 3D, timelapse, multichannel live-cell microscopy

🧵1/N

[Anup Jha @Anupjha59]

@DrVermaNandini @TnbcL @CRI_ACTREC @ACTREC_TMC Congratulations to all the authors.😊

[Nature Reviews Cancer @NatureRevCancer]

FINALLY 🥁.. our top most downloaded article of the year is…. 🥁 🥁🥁

Why do patients with cancer die? By @thomasrcox, Eric Sahai and colleagues

https://t.co/q8xFgq6ZWC

@crick.ac.uk @natrescancer @GarvanInstitute @UNSW @TheCrick
@NatResCancer #NRCtop10of2024

[Department of Biotechnology @DBTIndia]

📢Call for application: TATA Innovation Fellowship 2024-2025

A highly competitive scheme instituted by @DBTIndia, Ministry of Science & Technology, Govt. of India to recognize and reward scientists with outstanding track record in biological sciences/Biotechnology to find innovative solutions to major problems in health care, agriculture, environment and other allied areas related to life sciences and Biotechnology.

For More Information: https://t.co/ZIfp1DD8Yk

#fellowship #innovation #Biotechnology

@DrJitendraSingh @rajesh_gokhale

[Blood Advances @BloodAdvances]

VEN plus HMA induces superior response rates in patients with R/R AML than conventional salvage therapy. https://t.co/XJOf2OP3Kd #myeloidneoplasia #clinicaltrialsandobservations