I’m so excited to share this update on @Conception –
We’ve generated the first early human eggs derived from stem cells.
This is a big deal -- the potential to redefine fertility is real.
Reawaken the magic.
Celebrate 20 years of PAN’S LABYRINTH with stunning new artwork by James Jean. The film returns to theaters in 4K, 3D and Barco HDR. Experience the masterpiece.
Only in theaters October 9.
Dolly Parton has entered the trucker stop business. Here's a special look at Dolly's Tennessean Travel Stop in Cornersville, Tenn., that is officially open for business.
As a coder how did I ever get along without ChatGPT? Yah, sometimes it’s a bit of an idiot-savant but if you understand it’s quirks it is one hell of a productivity multiplier.
We've started tackling one of the central bottlenecks in testing longevity interventions in humans: measurement.
Two @ARPA_H projects, THRIVE and VITAL-H, are taking on that problem from different sides.
THRIVE is developing the PROSPR Intrinsic Capacity score, a way of measuring the functions people need to keep living well as they age, including cognition, mobility, vitality, and sensory function.
VITAL-H is testing whether Intrinsic Capacity can serve as a functional endpoint for aging trials, while also testing rapamycin, dapagliflozin, and semaglutide as possible interventions to preserve function with age.
Together, they are an attempt to move toward a longevity field with better truth-seeking capacity, enabling more and better trials of interventions that add healthy years to life.
Read more on THRIVE and VITAL-H here:
https://t.co/9tEkai1BKc
https://t.co/HeSlIFXdq4
We could be the last humans to age and die on schedule.
One injection from David Sinclair's lab already made old, blind mice see again, and in 2026 the FDA cleared it for people.
Here's the science nobody's ready for (THREAD):
This longevity scientist raised $1.8 billion with $180 million coming from Sam Altman to extend human lifespan.
After finishing his latest interview, I collected 9 findings he exposed that left me shocked:
1. Humans are naturally built to avoid exercise:
“Early detection can save an awful lot of lives, I think I’m evidence of that.”
Ann joined the NHS-Galleri trial evaluating a multi-cancer early detection (MCED) test hoping her participation might help others. She never imagined it would help her, too.
Watch her story and learn more about the NHS-Galleri trial: https://t.co/35Vkh5jFlL
The overall sensitivity in study participants with colon/rectum cancer was 82% (43.3% for stage I, 85% stage II, 87.9% stage III, 95.3% stage IV).
Some LC-36 updates. Now that we’ve had access to the pad and integration facility we can share a bit of good news. The propellant farm, oxygen, liquid hydrogen and LNG tanks are all in good shape. This is good luck because these are very long lead items. The water tower is also good. The big support tower is damaged, but it can be repaired in place rather than torn down and replaced. The booster “Never Tell Me The Odds” and the three GS-2s that were onsite in the integration facility also look good.
I’ve seen some speculation that we might move directly to the 9x4 configuration, but we won’t do that. Rate manufacturing of 7x2 is going well, and we’re going to continue that at pace as planned and store the stages for use. In addition, we had already been working for some time on eliminating our transporter-erector in favor of an alternative vertical conop, and we’ll now go directly to that; so we don’t need a new transporter-erector.
We will fly again before the end of this year. Gradatim Ferociter.
PATHFINDER 2 data being presented today at #ASCO26 offer new evidence on the safety and performance of a multi-cancer early detection (MCED) test when used alongside recommended #CancerScreenings.
Review the results from the largest #MCED interventional study in North America: https://t.co/mmkvyFFMMf
RX Only. See Important Safety Information: https://t.co/Mx2Czka4Bj
🧵 6/6
The charge of Taffy 3 saved the landing force in Leyte Gulf. Naval historian Samuel Eliot Morison later wrote of that morning:
"In no engagement in its entire history has the United States Navy shown more gallantry, guts and gumption than in the two morning hours off Samar."
Commander Ernest Evans was posthumously awarded the Medal of Honor. He was the first Native American in the United States Navy to receive it. The USS Johnston was awarded the Presidential Unit Citation.
The wreck of the Johnston was lost for over 75 years.
In 2019 explorers located a Fletcher class destroyer on the edge of an undersea cliff in the Philippine Sea. In 2021 a manned submersible descended more than 21,000 feet, over four miles down, to reach her. It was the deepest shipwreck dive in human history at the time.
They found her bow upright and intact. The hull number was still visible on the steel.
The team that found her left everything exactly where it lay. The director of the Naval History and Heritage Command called the wreck a hallowed site and said the story of the Johnston and her crew was a perfect example for modern sailors of the honor and courage of those who came before them.
A tiny destroyer that charged the largest battleship fleet in the world.
A captain who promised to go in harm's way and kept his word.
327 men who bought thousands of American lives with their own.
I post a story like this every single day. Most people never see them. Follow so you don't miss the next one.
Harry Truman left the White House with almost nothing.
No large fortune.
No presidential pension.
No motorcade waiting to carry him into retirement.
On January 20, 1953, Harry and Bess Truman climbed into their own Chrysler and drove themselves home to Independence, Missouri.
His approval ratings were low. Critics called his presidency a failure. Much of Washington was relieved to see him leave office.
What shocked many people later was how little money a former president actually received at the time.
Truman’s only steady income came from a small Army pension worth just over one hundred dollars a month. Financial pressure became so serious that he reportedly needed bank loans simply to cover daily living expenses.
The situation became so embarrassing for the country that Congress eventually created pensions for former presidents.
But Truman never spent his retirement chasing sympathy or public praise.
Back in Independence, he returned to a simple routine. He walked through town without heavy security. He answered his own telephone. He personally responded to letters from ordinary Americans.
On his desk remained the famous sign:
“The buck stops here.”
While Truman lived quietly, the impact of his presidency continued growing.
The Marshall Plan helped rebuild Europe after World War II.
The Truman Doctrine became a foundation of American Cold War policy.
In 1948, he ordered the desegregation of the United States military despite fierce political opposition.
When General Douglas MacArthur publicly challenged presidential authority during the Korean War, Truman removed him from command, protecting civilian control of the military even though the decision damaged his popularity.
Then history delivered one final moment of recognition.
In 1965, President Lyndon B. Johnson traveled to the Truman Library to sign Medicare into law. During the ceremony, Johnson handed the first Medicare cards to Harry and Bess Truman.
It carried special meaning because Truman had pushed for national health insurance decades earlier and faced enormous backlash for it at the time.
By the end of his life, public opinion had changed dramatically.
The man once dismissed as weak and unpopular came to be viewed as one of the most consequential presidents of the twentieth century.
Harry Truman never chased applause.
He simply accepted responsibility for difficult decisions and lived long enough to see history reconsider them.
Story based on historical records. This post is for educational purposes.