Arutha K

Brazil Family Chair in Spatial Medicine, UQ & WRI (Views my own)

[Arutha K @aruthak]

Let's get behind this amazing collaboration between @XboxANZ @Xbox @CureCancerAu to raise vital funds for early career cancer researchers @UQMedicine @UQ_News @TRI_info @Qld_SBC! 💪❤️ #GamingForACure #CancerResearch #MakingADifference 🎮🔬👩‍🔬

[Arutha K @aruthak]

https://t.co/k7RQO5EHHJ Dissecting non-small cell lung cancer (NSCLC) with blood proteomics - from surgical to immunotherapeutic responses

[Wesley Research Institute @WesleyResearch]

Congratulations to WRI researchers Professor John Fraser AO and Associate Professor Arutha Kulasinghe
@aruthak on being named among @couriermail 60 most powerful health figures in #Queensland!

@CCRG_Research @Qld_SBC

Read more 👉 https://t.co/WorQpqZWWT

[Satchin Panda @SatchinPanda]

Can sleep’s core benefits be delivered without actually sleeping?
Scientists induced sleep-like neuronal “off periods” during wakefulness in mice, reducing local sleep pressure, weakening synaptic strength, and even restoring memory consolidation during sleep deprivation. The findings suggest key functions of sleep may depend on specific brain activity patterns rather than sleep itself. #SleepScience #Neuroscience #Memory
https://t.co/K5ImYi7bKI

[Nav Toor @heynavtoor]

A GUY AT GOOGLE DEEPMIND MADE AN ISOMETRIC PIXEL-ART MAP OF NEW YORK CITY AND PUT IT ON THE OPEN WEB FOR FREE

it's called https://t.co/8fAASvEmXT

you open the tab and the city is just sitting there in classic SimCity 2000 isometric pixel art. you scroll. and it keeps going. and going.

i zoomed in on midtown and i could read the H&M signage in times square. in red. as actual pixel-art letters on the side of a building.

i could see the crystalline spire of the Bank of America Tower poking out of a clump of skyscrapers. individual rooftop HVAC units. tiny green roof gardens. the little driveway loops in front of the hotels.

he estimates the map needs roughly 40,000 tiles. nothing is a placeholder.

the guy who made it is Andy Coenen, a senior staff engineer at Google DeepMind. he is not a pixel artist. by his own admission he is "a former electronic musician."

what he actually did is kind of insane:

> pulled NYC's geometry from the Google Maps 3D tiles API

> fine-tuned an open-source image model (Qwen-Image-Edit) on ~40 hand-paired examples of "satellite tile → pixel art tile"

> spun up 50 parallel instances on rented GPUs and generated tens of thousands of tiles in a few hours

> the fine-tune cost him 12 bucks

his own stated mission for the project, verbatim, is one sentence: "what's possible now that was impossible before?"

apparently the answer is "one engineer can pixel-art most of a metropolis for the price of a sandwich."

and the wildest part to me is he didn't sell it. no signup. no paywall. no NFT. you open the URL and the city is yours to wander.

the post landed at 1,325 points on Hacker News and topped bestofshowhn's 2026 list.

we live in a timeline where a senior engineer at one of the largest AI labs on earth spent his nights pixel-arting Manhattan for fun and then gave it away.

the internet is healing.

[Rong Fan @RongFan8]

Totally over the moon 🤩 , our paper on charting human cellular senescence in aging and disease is on the cover!! It highlights the collective efforts and the first wave of publications from NIH @sennetresearch consortium to map senescent cell states, heterogeneity and niches!!

[Rong Fan @RongFan8]

🤩 spatial panoramic in vivo CRISPR screen via Perturb-DBiT 🤩 Excited to share our collaborative work with @sidichen lab and many outstanding collaborators, now published in Nature Biotechnology!
https://t.co/swMT8pJajh

[Satchin Panda @SatchinPanda]

Why do we age? Evolution may hold the answer.
Because natural selection weakens later in life, genes that boost early survival and reproduction can persist even if they contribute to aging and disease decades later. New advances in genetics and multi-omics are helping uncover why lifespan varies so dramatically across species—and how we might extend healthspan. #Aging #Longevity #Genetics
https://t.co/bTNWk3FoZF

[Journal of Experimental Medicine @JExpMed]

#Myeloid diversity in tumors: shaped by genes, location, and time. Review by Maria Nogales-Pons, Mariola Munárriz-Paños, Teresa Aceña-Gonzalo, & María Casanova-Acebes @Casanova_Acebes: https://t.co/jjWBCjZ9UX

📘 Part of JEM #Cancer Collection: https://t.co/YPWs2KQyqx
#EACR2026

[Wesley Research Institute @WesleyResearch]

Celebrating Associate Professor Arutha Kulasinghe @aruthak , Scientific Director of the @Qld_SBC, who has been recognised in @couriermail Power List today as a leading figure in QLD's science and technology sector.

Read more at - https://t.co/vBdO54VovC

[NEJM @NEJM]

Original Article: Daraxonrasib or Chemotherapy in Previously Treated Metastatic Pancreatic Cancer (phase 3 RASolute 302 trial) https://t.co/y4G27hfORg

#ASCO26 | @ASCO

[Parmita Mishra @parmita]

RAS finally getting drugged is one of the great stories in modern biology, and almost nobody outside oncology understands why it's such a big deal.

YOU'LL LEARN SOMETHING AWESOME TODAY.

i am going to keep this as understandable (and simple) as i can.

OPEN THE THREAD.

🧵

[NEJM @NEJM]

Presented at #ASCO26:

Among patients with previously treated metastatic pancreatic ductal adenocarcinoma, the RAS(ON) inhibitor daraxonrasib led to significantly longer overall survival and progression-free survival than chemotherapy. Full phase 3 RASolute 302 trial results: https://t.co/xwLWBZYRzq

@ASCO

[SEOM @_SEOM]

Toda la Plenaria de #ASCO26, en pie para aplaudir el trabajo que cambia la práctica clínica en cáncer de páncreas. Investigación para mejorar la supervivencia de los pacientes oncológicos 🙌🏻🙌🏻🙌🏻
📹 @Tony_Calles

[Eric Topol @EricTopol]

Just published @Nature
Very impressive study of gene expression and hallmarks of aging across 4 mammalian species (including humans), by @gladyshev_lab. Transcriptomic clocks add to epigenetic, organ and cellular clocks for predicting health outcomes. Example of a few proteins found with prediction of disease/event risk in Figure below
https://t.co/t3HDtDAfOT

[Wesley Research Institute @WesleyResearch]

Researchers from @Qld_SBC have identified a promising set of blood-based biomarkers that could transform how non-small cell lung cancer (NSCLC) is detected, monitored and treated.

👉 Read more at https://t.co/ZLdo07X1z5

🩸 Study - https://t.co/nzac6LkOOw

@aruthak

[Alistair Forrest @Al__Forrest]

Welcoming @aruthak to #HCA2026Asia!

Advancing #SpatialBiology and #PrecisionMedicine.

See recent whole-transcriptome spatial profiling of lung cancer TMAs. https://t.co/XgdpiwqU2N

Join us in Fremantle: https://t.co/fmhyNvJlJv

Publications: https://t.co/eWO5VYeOiA

[Fabian Theis @fabian_theis]

Excited to share our RegVelo paper in Cell
https://t.co/ZAnQphaXsg

We unify RNA velocity + GRNs into one model → better OOD prediction of perturbations (e.g. gene KOs), with examples incl. neural crest KO predictions 🔬

Big thanks to W Wang, Z Hu & T Sauka-Spengler 🙏

[Jinmiao Chen Lab @CJM_lab]

Excited to share our latest work in @NatureGenetics (https://t.co/ID3uRacigt). We introduce SpaMosaic, a new computational method designed to advance spatial omics by mosaic integration of diverse datasets with partially overlapping modalities.

[Ron Alfa @Ronalfa]

Great new study dropped from @aruthak with 100s of patients of spatial whole transcriptomics data, check it out:

[Arutha K @aruthak]

Huge thanks to our funding partners who made this study possible: @nhmrc @CureCancerAu @UQ_News @WEHI_research @YaleMedicine @Qld_SBC @WesleyResearch @bhuva_dd @chinwee10

[Arutha K @aruthak]

We mapped the spatial landscape of lung cancer. All 18,935 transcripts of it🧬🫁Introducing the Clinical Lung Cancer Tissue Atlas. A pathology-annotated, single-cell whole transcriptome mapping of #NSCLC biopsies using. Every cell. Every neighbourhood.
https://t.co/RrrQajXLKS

[Arutha K @aruthak]

Independent cohort and platform validation also replicated our compositional findings across histotypes and sex. 💪