Mike Lee

Microbial ecologist/bioinformatician PhD 👽 | Bioinf-beginners go to | For phylogenomics, GToTree :)

[Mike Lee @AstrobioMike]

New music alert!!

In my pre-science life I used to make music 🎸🎤🎵 And I just put out a new song!

The link below will get you to your preferred streaming/music service. Check it out 🙂

https://t.co/PZcIVyUb5b

[Satoshi Kawato 川戸 智 @KawatoSatoshi]

Circular genome comparison is now live in #gbdraw! 🚀 The built-in LOSATN instantly runs pairwise alignments and generates homology rings for your sequences, 100% in your browser! Try it out: https://t.co/ZA4FoGdp7l #bioinformatics #genomics #microbiology

[Michael 英泉 Eisen @mbeisen]

How do you publish this tree and claim it's a success???!!!

[Cameron Thrash @jcamthrash]

Microbe Decoder uncovers functional traits of microbes in microbiome datasets https://t.co/7vCQlPL1VU

[Satoshi Kawato 川戸 智 @KawatoSatoshi]

🧬Collinearity Analysis is here in #gbdraw v0.11.0! You can easily detect and visualize synteny and collinearity blocks using LOSATP. You can instantly align the entire diagram based on a shared ortholog!
Try it now: https://t.co/ahqoRxbDHT
#bioinformatics #genomics #microbiology

[Steven Salzberg 💙💛 @StevenSalzberg1]

Welcome @aphillippy to @JohnsHopkins in both @JHUCompSci and @JHUBME, as a new @JHU_BDPs professor starting today! https://t.co/Szp1eR98Zi

[GAMA Miguel Angel 🐦‍⬛🔑 @miangoar]

The DeepClust database, with 19B protein sequences clustered into 544M non-singleton clusters, hwas finally published after 3 fucking years. A lot of improvements will come from using these sequences in our analyses :)

paper
https://t.co/xUugkrbUdC

DB
https://t.co/lBJAqXxiAW

[Michael 英泉 Eisen @mbeisen]

For anyone coming upon this work for the first time (it was originally published two years ago on @biorxivpreprint before being republished by @nature this week), it is already the subject of extensive discourse (c.f. https://t.co/AL05z0f9We) and multiple follow-up papers (e.g. https://t.co/eEiHCcn1cL) which are essential to understand when thinking about this paper.

[A. Murat Eren (Meren) @merenbey]

How every layer of science's "self-correcting machinery" failed when Iva Veseli and I simply wanted to reproduce the findings of a high-profile study on gut microbiome and autism:

https://t.co/cyTY7q6Lv5

[Bloomberg @business]

Hungarian Prime Minister Viktor Orban conceded defeat to Peter Magyar in Sunday’s parliamentary election, according to the opposition leader https://t.co/mYz186Qb7A

[Mike Lee @AstrobioMike]

@jlsteenwyk @phylogenomics Cool, Jacob!

[🧬Jacob L Steenwyk @jlsteenwyk]

NEW tool: introducing ClustKIT, an accurate #protein sequence clustering

ClustKIT performs particularly well in the twilight zone of #sequence identity (L panel; low identity thresholds; Pfam benchmark w/ 22,343 sequences from 56 families)

ClustKIT also scales well (R panel)

[Satoshi Kawato 川戸 智 @KawatoSatoshi]

gbdraw v0.9.1 is out now on Bioconda!
Easily visualize microbial genomes and enjoy the #gbdraw web app completely offline.
📦 Install via Bioconda: https://t.co/sjtaqHXHsk
🌐 Try the online app: https://t.co/ahqoRxbDHT
#bioinformatics #genomics #microbiology #visualization

[Steven Salzberg 💙💛 @StevenSalzberg1]

In my latest column, I explain some of my reasons for being deeply skeptical about AI models that claim to understand DNA, genes, and genomes: https://t.co/83cv4HqVMB

[Evgenii Protasov @protasov_evgeni]

Toward a genomic understanding of the tree of life
#microbiology #evolution #eukaryotes #TreeofLife
https://t.co/A12GZde2Wg

[David Sinclair @davidasinclair]

This paper took us 13 years and is one of the longest papers ever in Cell. Check it out & judge for yourself
https://t.co/Ra0CX1i5zt

[Trends in Genetics @TrendsGenetics]

Formation and maintenance of genome gigantism https://t.co/dDIzR5Yykb

[Jim Shaw @jim_elevator]

Myloasm, our long-read metagenome assembler, is now published! w/ Max Marin & @lh3lh3

Very rewarding after > a year of development and countless hours thinking about assembly. Thanks to beta testers, Li lab, and reviewers for helpful feedback.

Link: https://t.co/Hjr8hHiupP

[Cameron Thrash @jcamthrash]

Clustering the protein universe of life using DIAMOND DeepClust https://t.co/YDcBgPSd9f

[Prof Peter Hotez MD PhD DSc(hon) @PeterHotez]

Seriously? I make low-cost vaccines that reached 100 million people, bypassed big pharma, didn’t make a dime, and saved 300,000-500,000 lives, and they focus on a junk food joke I made 6 years ago, this Rogan crowd, a bunch of candy-ass lightweights

[Mike Lee @AstrobioMike]

@stolinski It’s crazy how may replies here missed your point entirely 🤦‍♂️