@RealCandaceO Candace be careful. Brandon Biggs who saw in a prophetic vision about Trump being shot in ear has seen you being taken out by crazy leftist in a white van.
I never give price predictions. I focus on explaining the mechanics of how certain price levels become structurally necessary.
The US dollar became the world’s reserve currency because all the value needed for final settlement concentrated around it. That’s a fact.
In this new tokenized digital economy, liquidity and final settlement are everything.
And right now, the exact same concentration of value that lifted the dollar is happening around XRP.
For $XRP to actually function as the backbone of global reserve settlement at scale, it has to trade at a price high enough to absorb massive liquidity without choking.
When you put the infrastructure, the adoption trajectory, the tokenized asset flows, and the pure mathematics of settlement together… XRP belongs in the hundreds of thousands of dollars per token.
I haven’t said this publicly in a very long time. But I’ve always known it.
NEW ARTICLE: RESEARCH: NICLOSAMIDE in CANCER and other diseases - 2025 Review Paper from Henan, China
NICLOSAMIDE was approved by FDA in 1982 for treating tapeworm infections, and was designated an essential drug by WHO.
NICLOSAMIDE in CANCER Mechanisms:
1. Mitochondrial uncoupling - this is its major anti-cancer mechanism
Niclosamide acts like a mild “leak” in the mitochondrial membrane, letting protons slip across without making ATP. This increases oxygen use, lowers ATP levels, raises AMP/ATP ratio & activates AMPK (energy sensor) to inhibit mTOR (slows down cancer cell growth).
Cancer cells, which often rely on inefficient energy pathways (Warburg effect), are especially vulnerable.
This can lead to inhibition of ATP synthesis, exhausting cellular energy reserves, metabolic stress, and cell death.
2. Signal pathway modulation - It inhibits several “pro-cancer” pathways, including:
- Wnt/β-catenin (important in cancer proliferation, especially colorectal).
- mTOR (controls cell proliferation, growth and metabolism).
- Notch pathway (controls proliferation, growth, angiogenesis and cellular migration)
- STAT3, NF-κB, etc. (cancer survival, proliferation).
- Promotes apoptosis (programmed cell death) and reduce inflammation.
3. Combination with existing chemotherapies
4. Addresses Multi-Drug Resistance - by enhancing production of reactive oxygen species.
OTHER DISEASES - beyond cancer, Niclosamide’s versatility includes:
Anti-bacterial - strong in vitro activity against resistant gram-positive bacteria.
its antibacterial activity involves altering bacterial morphology, reducing intracellular ATP, and inhibiting α-HL secretion (Staph Aureus)
it inhibits all three toxins of Clostridium difficile by targeting a host process essential for toxin entry into colonocytes. In a mouse model, it reduced both primary disease and recurrence without affecting gut microbiota diversity
it demonstrates marked inhibition of vancomycin-resistant Enterococcus faecium (VRE)
It effectively eliminates H. pylori adhesion/invasion
Anti-Fungal - demonstrates impressive antifungal effects in vitro and in vivo niclosamide effectively disrupted and removed biofilms of drug-resistant Candida albicans and Candida auris by targeting mitochondrial respiration
Anti-Viral - Niclosamide could have action against SARS-CoV, MERS, Zika, Hepatitis C, Ebola, EBV
Niclosamide inhibits viral replication by reducing mTOR activation and prevents viral entry
inhibits virion production in EBV-infected cells while showing cytotoxicity and inducing cell cycle arrest
demonstrates strong activity against RSV in vitro, with a 94 % inhibition rate
suppresses Hepatitis C replication and reduces viral load
Metabolic disorders (e.g., Type II Diabetes, fatty liver): Mitochondrial effects and AMPK activation can improve energy balance and reduce fat accumulation.
Diabetes: modulates metabolic pathways, improves insulin sensitivity
Fatty liver (NASH, NAFLD) - reduces hepatic inflammation
Neuropathic Pain - reduces inflammation by inhibiting NF-kB, STAT3
alleviates pain and nerve damage
Rheumatoid Arthritis - inhibits NF-kB activation
reduces secretion of IL-6 and other inflammatory cytokines,
blocks migration and invasion of RA fibroblast-like synoviocytes.
Psoriasis - inhibits keratinocyte hyperproliferation and reduces inflammation by downregulation of STAT3, NF-kB.
Airway Diseases (Asthma, Cystic Fibrosis, COPD)
Niclosamide inhibits certain Ca-activated Cl channels involved in mucus hypersecretion & bronchoconstriction (reduces mucus production & secretion.
it blocks release of mucus and inflammatory mediators which reduces bronchoconstriction.
anti-fibrotic agent for lung fibrosis - Niclosamide downregulates expression of collagen proteins and inhibits pro-fibrotic cytokines.
Endometriosis - Niclosamide targets STAT3 and NF-kB, reduces proinflammatory cytokines and reduces endometriotic lesion growth.
ALS
In vivo experimentation involving two ALS mouse models demonstrated slowed disease progression, enhanced survival rates, and reduced motor neuron loss and muscle atrophy.
At the molecular level, niclosamide inhibited dysregulated pathways such as STAT3 and mTOR, reduced gliosis, and dampened inflammatory signaling
niclosamide has shown remarkable potential by efficiently inhibiting the expression of S100A4, a Ca2+-binding protein frequently upregulated in reactive microglia and astrocytes in ALS models. This inhibition contributes to reduced microglial reactivity, cytoskeletal changes & inflammation in ALS
Systemic Sclerosis - inhibits STAT3, AKT, and Wnt/β-catenin pathways
reduced immune cell activation
reversal of skin and lung fibrosis and reduced rate of inflammation
CONCLUSION:
Ivermectin, Mebendazole and Fenbendazole are leading the repurposed drug revolution
but Niclosamide is the most promising of the other anti-parasitics!
"People get confused sometimes they think an economy is money. Money is a database for exchange of goods & services. Money doesn't have power in & of itself. The actual economy is goods & services"
一 Elon Musk
Larry Fink just confirmed what we’ve been saying for years, every central bank currency will be digitized, every ETF and asset will be tokenized, and they’ll all need a cross-border settlement layer.
The plumbing of global finance is being rebuilt, and #XRP is the foundation.
“Joe Kent warned about this…”
‼️Netanyahu “Doomsday” Bombing‼️
Now:
• Netanyahu pushes deeper into Lebanon
• West Bank violence escalates
• Iran tensions rise
And the war narrative is starting to crack.
@TokeMalone
so you’re telling me 5 min before trump announced a ceasefire, someone in his inner circle loaded up on a perfectly-timed trade (long stocks, short oil), walked away with billions, and then we the plebs are told $8 gas is just “the price of freedom” so just get less starbucks ???
BOMBSHELL: Iran offered to give away ALL of its enriched uranium during peace talks in Geneva. The British thought it was a credible offer. Hours later, Trump started bombing Iran anyway. The US didn't want peace, they wanted war.
Joe Kent:
Iran wasn’t the immenent Threat… it was Israel — The only reason we conducted this attack against Iran was because the Israeli’s attacked first, and we knew in retaliation, that would put American forces at risk.
Marco Rubio himself even said this..
“I think it’s fine thaw e offer defense to Israel, but when we’re providing the mean for their defense, we get to dictate the terms when they get to go on the offensive — and the Israeli’s felt emboldened that no matter what they did, or situation the put us in, they could take this action and we would have to react.”
https://t.co/HErBmTzHCC
Joe Kent drops a bombshell, revealing that the Israeli lobby in DC manipulated intelligence to push the Trump administration to treat Iran as an imminent threat when it wasn’t.
He names people like Mark Levin as playing a major role in repeating propaganda talking points to the public.
He says this manipulation of intelligence destroyed the negotiations President Trump had planned with Iran.
🚨 BREAKING: Retired Marine Joey Jones just NAILED IT on VOTER ID: "If you can't handle proving you're a citizen...I don't give a D*MN if you don't vote again, because I don't CARE what you have to say!"
“If that’s mean or elitist, I really don’t care! And if you’re a politician and those are the people you’re advocating for, I really hope you lose too!" 🔥🔥
“If you’re going to be in the greatest and most prosperous country in the world, you should want to take part in it and give a little to do it."
"JFK said ‘don’t ask what your country can do but ask what you can do for your country’: You can find your birth certificate and go get a free ID to vote. That is what you can do for your country!" 🇺🇸
PASS THE SAVE AMERICA ACT.
H/t @TVNewsNow@Johnny_Joey