Aude Dorison

Team Leader / Senior Research Officer at @MCRI_for_kids 🔬 #kidney enthusiast 👩‍🔬
Disease Modeling Team #stemcell #organoid

[Aude Dorison @AudeDorison]

Thrilled to announce the publication of this research paper on NPHS2 variants and their impact on Podocin trafficking unraveling new insights on steroid-resistant nephrotic syndrome pathophysiology using iPSC-derived kidney organoids. @MCRI_for_kids #kidney #organoid #stemcells

[JASN_News @JASN_News]

One commonly mutated gene in steroid-resistant nephrotic syndrome is NPHS2. This study found that human kidney organoids created from missense variants of NPHS2 revealed reduced PODOCIN degradation and mistrafficking https://t.co/hCB4OIU9Ko

@kynanlawlor @Moinsaleem @Mithunbge

[Jessica M Vanslambrouck @JMVanslambrouck]

Pleased to be sharing this chapter written with Nils @LindstromLab for Current Topics in Developmental Biology! Here we dive into how #nephrons establish proximal-distal patterning during #KidneyDevelopment & what this means for #StemCell-derived nephrons: https://t.co/sAXMLzl1Jh

[Sean Wilson @sbwil91]

We are hiring!

Postdoctoral position available in the Little Group, Copenhagen University.

We study kidney organoids using microscopy, transcriptomics, bioinformatics, bioengineering... all the fun stuff!!!

https://t.co/xW8y9UMIha

[Aude Dorison @AudeDorison]

@holly_voges @heartfoundation Congratulations Holly!!! 🎉👏

[Aude Dorison @AudeDorison]

First ASN since 2015! Different year, same place #SanDiego Very excited to be here and looking forward to enjoying fantastic science! #KidneyWk #kidneyweek2024 #KidneyWk2024

[Aude Dorison @AudeDorison]

@KidneyCathy @RCPI_news Congratulations Cathy 🎉🎉

[Aude Dorison @AudeDorison]

Very excited to be a finalist in the #reNEW ARTxSCIENCE 2024 image competition. Many thanks to everyone who voted for my submission. Congratulations to the other finalists who submitted fantastic images. I am glad #kidney share the spotlight with you today! 🔬✨

[reNEW @reNEW_Global]

#reNEW ARTxSCIENCE 2024 FINALISTS:
The public has voted, and our 12 finalists have been chosen for the reNEW ARTxSCIENCE 2024 competition!

Congratulations to: Oscar Bay Axelsen, Maria Giovanna Garone, Beatrice Gabbin, Lieke Stockmann, Amy Lucassen, Ben Johnson, Fangchen Liu
Hayley Pointer, Charlotte De Henau, Janine Melsen, Denis Bienroth, and Dr Aude Dorison, PhD.

Who will win the reNEW ARTxSCIENCE 2024 competition? Our esteemed jury is now getting ready for selecting the winner.

Announcement on October 9th on Global Stem Cell Awareness Day.

See the submissions of the finalist's at https://t.co/WEQDw6xJ5A

A huge thank you to all of you who submitted for this year’s competition.

We hope you will continue to support the reNEW ARTxSCIENCE Competition and join us next year in raising the awareness of stem cell research and it's potential to transform the lives of people with e.g. incurable diseases.

@GlobalLumc @LUMC_Leiden @UCPH_Research @MCRI_for_kids @novonordiskfond

[Murdoch Children's Research Institute (MCRI) @MCRI_for_kids]

Congrats to #MCRI's Dr Kiymet Bozaoglu who has received a New Investigator Award to examine the impacts of #NF1 on brain function. NF1 causes various benign tumours and is linked to #ADHD & #autism. | @Kiymet_b @DeptofDefense

➡️ https://t.co/49ANptACnB

[reNEW @reNEW_Global]

#ARTxSCIENCE 2024:

Discover the power of science combined with artistic expression and learn about the potential of stem cell research to transform the lives of people.

Help up find a winner of the best fusion of #ARTxSCIENCE on https://t.co/HOjbeIgTm7

#Kidney Glomeruli on Fire’

#Kidneydisease is often viewed as a disease of adults, but 1 in 15,000 children present with kidney disease as a result of inherited #gene variants. The research of Al Dr Aude Dorison and her team aims at increasing knowledge of genetic kidney disease in children and identify novel and effective therapeutic strategies.

Children with changes in specific genes can present with #kidneyfailure in the first few years of life and no other treatment than dialysis or transplantation currently exists. By generating #minikidney from patient-derived #stemcells, we are able to improve our understanding of the cellular and molecular mechanisms driving the disease. This provides us with an opportunity to design therapies specifically correcting the defects identified.

The team has found the underlying cause of one of the most common forms of genetic nephrotic syndrome. They have also developed a miniature stem cell-based model of the disease with which we will screen thousands of compounds looking for those able to correct the molecular problem.

Here we see a glomerulus in a stem cell-derived mini-kidney. The cells lighting up in the centre are podocytes, a key cell type for the filtration of the blood into the urine.

@MCRI @LUMC @UCPH

Submission by Al Dr Aude Dorison, PhD, (Senior Research Officer), Ms Rachel Lam and Ms Irene Ghobrial, Prof Melissa Little Lab, #reNEWMelbourne, Australia

[Jessica M Vanslambrouck @JMVanslambrouck]

Great to see this paper out now in JVI @JVirology: using stem cell-derived enhanced kidney organoids to gain further understanding of SARS-CoV-2 entry mechanisms in human kidney cells @MCRI_for_Kids @TheDohertyInst (https://t.co/n78tbw4wmB)

[Aude Dorison @AudeDorison]

@JamesMc2327 @heartfoundation @PorrelloER @DaveElliott_1 Congratulations James! This is absolutely fantastic 🎉

[reNEW @reNEW_Global]

.@JMVanslambrouck & team from #reNEW Melbourne @MCRI_for_kids have published an advanced way to create #stemcell derived kidneys with improved proximal tubules in @NatureProtocols, to accelerate progress towards treatment for #CDK in adults and children.
https://t.co/oLU2eyfrQg

[reNEW @reNEW_Global]

Our #reNEW #Melbourne team is looking for a Research Assistant / Research Officer in the Bioinformatics Facility, based in the @MCRI_for_kids Transcriptomics and Bioinformatics group 👇
https://t.co/wkuUnB41tl

[Aude Dorison @AudeDorison]

Want to hear about what MCRI researchers have in store for our upcoming Meet the scientists event? Head to @MCRI_for_kids
Instagram page to find out!
@kidney_tom @kynanlawlor #kidney
#kidneydisease #kidneyorganoids #stemcells #childhealth https://t.co/ZAP7HKr11d

[Murdoch Children's Research Institute (MCRI) @MCRI_for_kids]

🫘👩‍🔬Join Prof Melissa Little & a panel of MCRI researchers to explore the latest advancements in #kidney stem cell research.
Engage with scientists & share your experiences as a patient.
#MeetTheScientists #KidneyResearch #StemCells
Register for FREE➡️https://t.co/FkizDRaqKk

[Aude Dorison @AudeDorison]

@inesmpsan @reNEW_Global It was great to have you joining the team for a month Ines. All the best back to Copenhagen and looking forward to continuing our collaboration 😃

[Aude Dorison @AudeDorison]

@LiddelowSA Western blot zoom meeting? 🤔😆

[Aude Dorison @AudeDorison]

Excited for this opportunity to present our latest research and engage with patients. Looking forward to this event! #kidney #stemcellresearch #patientengagement

[Murdoch Children's Research Institute (MCRI) @MCRI_for_kids]

🫘👩‍🔬Join Prof Melissa Little & a panel of MCRI researchers to explore the latest advancements in #kidney stem cell research.
Engage with scientists & share your experiences as a patient.
#MeetTheScientists #KidneyResearch #StemCells
Register for FREE➡️https://t.co/FkizDRaqKk

[Aude Dorison @AudeDorison]

@holly_voges @CellReports @MCRI_for_kids @reNEW_Global Congrats Holly and team! Well done! 👏🎉

[Aude Dorison @AudeDorison]

When your bestie is just incredibly talented! Congratulations @JMoreau83 !!! 🎉

[Alex Combes @AlexKoomz]

Congratulations to Dr Moreau ⁦@JMoreau83⁩ for another win in the annual ⁦@MicroMonash⁩ image competition!

[Murdoch Children's Research Institute (MCRI) @MCRI_for_kids]

MCRI is grateful to have received #MRFF funding & we’re highlighting some of these funded #research projects & clinical trials in a series of #MRFFinaMinute 📹 on #MRFFMondays.
This week we feature Prof Melissa Little’s research.
🔗https://t.co/Tpe5cVB8RV
https://t.co/wSWY1Nhraj