What happens to the brain when neurons fall silent?
In a new iScience paper, Auguste and the team show that silencing synaptic release via Snap25 deletion triggers circuit-specific astrocyte and microglial remodeling across the brain and spinal cord.
https://t.co/MzlOa3YNxJ
Thank you @PhyloBrain, you kept going for the most fundamental questions of brain evolution in spite of all the difficulties over the last two decades.
Collaborative work between the Mann and Molnár Groups at @OxfordDPAG have studied a small group of specialized brain cells to investigate how they play a powerful role in keeping us alert and helping our brains process sensory information (https://t.co/PdVzkJTA7X).
BREAKING NEWS
The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
We are excited to announce that Prof. Stefan W. Hell @StefanHellLabs will be our first keynote speaker in our Encephalon symposium 2023! Read more on our website. Follow us: https://t.co/KZGSc7TDlq! #encephalon2023
Our new paper on developing #brain demonstrates that phospholipid scramblase #Xkr8 is developmentally regulated in the mouse brain and required for postnatal axonal pruning. https://t.co/cPtlauuc6o
.@FGinhoux calls a new approach for exploring the role of microglia in neurodevelopment exciting, "but it is really just the beginning," he says. How do you think this method can benefit the field?
Read about the method: https://t.co/oy5IlFcCQZ
By @avaskham.
@AugusteVad
When does spontaneous and regulated synaptic vesicle release play a part in neuronal development? Is (a) axon outgrowth (b) establishment of synapses (c) neuronal communication? Read our review on the role of SNARE proteins in cortical development: https://t.co/vbCJmjtmx5
SPECIAL ISSUE OF THE JOURNAL OF ANATOMY ON HUMAN CORTEX DEVELOPMENT
The papers summarise the various aspects of human cerebral cortical development from the earliest stages of neurogenesis, to neuronal migration, differentiation and circuit assembly.
https://t.co/gaEZSYEuNd