Azmul Kabir Rabbi

Deputy Program Manager (Training)
Management and Training International Ltd. (MTI)

[CardiovascularCorner @TrackYourHeart]

Which medication is preferred to relieve symptoms of pericarditis after a heart attack?
A. High-dose aspirin
B. Ibuprofen only
C. Antibiotics
D. Insulin

[CardiovascularCorner @TrackYourHeart]

The Anatomy of the Aorta and Its Main Branches😍

[CardiovascularCorner @TrackYourHeart]

Complete Guide to Heart Anatomy
📸: @just_me_studying

[CardiovascularCorner @TrackYourHeart]

Endocrine signs and symptoms

[ABCL TECH @abcltech]

একটা প্রশ্ন: আপনার কোম্পানির সবচেয়ে বড় খরচ কোনটা?
বেশিরভাগ ক্ষেত্রে উত্তর: মানব সম্পদ।
এখন যদি বলি, সেই খরচের ৫০–৯০% কমানো সম্ভব?
এটাই হচ্ছে এআই নিয়োগের বাস্তবতা।

[CardiovascularCorner @TrackYourHeart]

Understanding Liver Enzymes: ALT, AST & ALP in Disease Patterns

[Science News @SciencNews]

The Immune Response

[Diego A. Díaz-García @diegoadiazg]

🧬 CRISPR 2.0–engineered T cell therapies.

Base and prime editing enable precise, programmable genome modification in T cells, reducing unwanted edits seen with CRISPR Cas9.
These platforms aim to enhance T cell fitness, expand targetable antigens, and simplify manufacturing, with multiple trials now underway in haematological and solid tumours.

📖 @NatRevClinOncol
DOI 👉🏻 10.1038/s41571-025-01072-4

#CánCare #immunotherapy #cellulartherapy #CRISPR #precisiononcology

[Science News @SciencNews]

How Brain cells communicate

[Trends Cell Biology @TrendsCellBio]

Oxidative stress in metastatic progression https://t.co/ruL2BAOUz2

[Science Magazine @ScienceMagazine]

In a new Science study, researchers describe MetaEdit, a strategy that enables targeted insertion of large DNA sequences into the genome of bacteria within the mouse gut environment.

📄: https://t.co/6NWVq3E6dI
#SciencePerspective: https://t.co/bCpiMHz4fO

[William A. Wallace, Ph.D. @WilliamWallace]

How the gut microbiome synchronizes with the brain’s circadian clock

This figure shows how the gut and brain communicate through neural, immune, endocrine, and metabolic pathways that are influenced by the body’s internal clock. The microbiome, hormones, and light–dark cycles interact to coordinate sleep, metabolism, stress responses, and inflammation across the gut–brain axis.

1️⃣ Central and peripheral clocks
The brain’s master clock in the suprachiasmatic nucleus (SCN) aligns daily rhythms with environmental light through the retinohypothalamic tract. Peripheral clocks, including those in the gut, follow signals from the SCN but also respond to feeding times and microbial metabolites.
🟢 Example: Disrupted light exposure or irregular eating can desynchronize the gut’s circadian rhythm, altering microbial composition and metabolic regulation.

2️⃣ Endocrine pathway
The hypothalamic–pituitary–adrenal (HPA) axis links stress and circadian timing through hormone signaling. Gut microbes influence HPA activation by releasing metabolites and cytokines that affect cortisol release.
🟢 Example: Certain bacteria such as Actinobacteria and Streptococcus modulate HPA activity, contributing to changes in inflammation and stress hormone output.

3️⃣ Immune pathway
Microbial components interact with immune cells in the intestinal mucosa, producing cytokines that reach the brain through circulation or vagal signaling.
🟢 Example: Lipopolysaccharides (LPS) and pattern-associated molecules from gut bacteria trigger IL-1β and TNF-α release, linking dysbiosis to neuroinflammation and altered sleep quality.

4️⃣ Metabolic pathway
Microbes regulate lipid and glucose metabolism through production of short-chain fatty acids and other metabolites that follow circadian patterns.
🟢 Example: Species like Lactococcus chungangensis and Ruminococcus bromii affect lipid metabolism, aligning energy use with the body’s day–night cycle.

5️⃣ Neural pathway
The vagus nerve transmits microbial and immune signals bidirectionally between gut and brain. Neurotransmitters and microbial by-products influence mood, stress, and cognition through this circuit.
🟢 Example: Cytokines and bacterial metabolites act on vagal afferents, shaping neural activity in regions that regulate alertness and emotional balance.

Together, these pathways demonstrate how the microbiome acts as a peripheral clock that integrates environmental cues, diet, and stress signals with the brain’s circadian system. When alignment breaks down, it contributes to insomnia, metabolic dysfunction, and inflammation across multiple organ systems.

https://t.co/HtR3nA6AZ3

[Johns Hopkins Medicine @HopkinsMedicine]

The history of medicine is more than just a few fun facts on an introductory slide. M.D./Ph.D. student Leigh Alon explores how understanding history is critical toward being a competent clinician and researcher. https://t.co/ajvOzHV6z4

[Science Magazine @ScienceMagazine]

In Science, researchers report the observation of dendritic nanotubes in brain tissue from mice and humans. The discovery suggests that the current understanding of the brain’s organization may be incomplete, overlooking a hidden layer of connectivity.

Learn more in a new #SciencePerspective: https://t.co/Vv42SiBcif

[Raihan Khan @RaihaKhanCS]

চ্যাটজিপিটি বা জেমিনি যখন সব করে দিচ্ছে, তখন কষ্ট করে পড়াশোনার দরকার কী? AI কি সত্যিই জ্ঞানের বিকল্প?

বিস্তারিত পড়ুন:

https://t.co/wW4bj1aQcT

[Visa Bangla @VisaBangla]

How to Apply and Submit Thai e-Visa Application Online 2025 from Bangladesh | Thailand Visa

Click to Watch Video on YouTube:
https://t.co/7CQKRW9S5z

[Raihan Khan @RaihaKhanCS]

How to Apply and Submit Thai e-Visa Application Online 2025 from Bangladesh | Thailand Visa

Click to Watch Video on YouTube:
https://t.co/58yoO36kS5

[Cancer Cell @Cancer_Cell]

From backstage to the spotlight: γδT cells in cancer https://t.co/TH5164xIHi

[Cancer Cell @Cancer_Cell]

Online Now: Spatial oncology: Translating contextual biology to the clinic https://t.co/StcUsdf0ro