🎙️Excited to announce the website for Ring That Bell 🔔 which I co-wrote w internationally acclaimed Irish country music artist @mags__mccarthy. It tells the emotional story of a cancer patient facing relapse and the fierce advocacy, support, and groundbreaking science that offer new hope.
#cancer #cancerresearch #immunotherapy #hope
https://t.co/K1SYmoiqHV
SCOOP: A Trump administration plan to give Americans easier access to unproven peptides was opposed by FDA drug staffers, who had limited input in drafting the policy.
https://t.co/vNYIiDq69Q
@YLeyfman@ISCTglobal@heMEGirl_MD@JulioChavezMD@AliceBertaina A big thank you to all of our ISCT Clinical Fellows for your participation and engagement during this inaugural course. Take home lessons on mentoring and team building to bring cell and gene therapies to patients were unifying themes.
Today we launched the Inaugural @ISCTglobal Clinical Applications Program for Fellows @PennMedicine - A selective, ISCT-funded two-day immersive program equipping clinical fellows with practical skills to advance cell and gene therapies from bench to bedside. Links in reply and watch for next year's courses
These extraordinary mRNA cancer vaccine results didn’t happen overnight - they happened through DECADES of hard work and dedication.
Katalin Karikó and Drew Weissman helped make mRNA usable. Pieter Cullis et al helped develop the lipid particles that deliver it into cells. Thousands of scientists, clinicians, trial volunteers and funders have kept this work moving forward through setbacks, funding uncertainty and enormous challenges.
That foundational work helped give us the mRNA platform for COVID vaccines. Now the results of this large phase 3 trial has confirmed that a personalized mRNA vaccine, added to immunotherapy, can help keep melanoma from returning.
All while this technology has been demonized and scientists and public health workers have been vilified. Still - they keep working. For the ultimate benefit of society.
We owe them our immense gratitude and support to keep going.
Treasury is right to try to protect national security. But we should watch for broad restrictions that could undermine our public health goals - impacting patient access to global innovation.
The new policy could curtail virtually any investment in Chinese biotech operations, including establishing labs, or entering into joint ventures, thwarting opportunities to bring Chinese innovation to American patients.
We need to focus equal attention on making our own process more efficient and competitive, especially Phase 1 trials and the IND stage. The discussion on this will be important. We must get this balance right and ensure Americans continue to benefit from the best global science.
Maybe honesty > authenticity? "Holmes takes advantage of our societal confusion between authenticity, or speaking one’s own truth, and honesty, in which one speaks the truth."
Great piece by @matthewherper in STAT. He reminds us of some of her lies, including one she told him on stage in front of an audience https://t.co/AG7qYcVABI via @statnews
The reporter who exposed Theranos loved the new Elizabeth Holmes documentary but says its ‘artistry’ shouldn’t obscure the fraud https://t.co/8VVsLnNK6Y
So @TylerShultz_ as a Theranos whistleblower. And he wrote the piece you need to read about ‘You Can See Everything.’
Elizabeth Holmes is still lying, he says. And the filmmakers, while creating a great piece of art, fall short on looking outside the walls of her apartment to document that.
One key detail: "My wife had to squeeze my arm to prevent me from jumping out of my seat in the theater and screaming, THAT IS NOT THE DEVICE."
Again, that device Holmes showed? It's not the one we're talking about!!!!
Having seen the film, I basically agree with Tyler's take.
https://t.co/EhgUWc90o0
I actually enjoyed “You can see everything” but people need to understand that this is not a documentary. And the device Elizabeth showed Nathan WAS NOT THE DEVICE
A few readers have taken me to task for “missing the point of the film,” which is apparently that Elizabeth Holmes is unknowable and everything is ambiguous. Here’s my response: She went after Tyler Shultz and Erika Cheung with everything she had. I was threatened with litigation on a daily basis for months on end. It was a ruthless cover-up of a breathtaking fraud, and she was at the controls. Just a little context for those who have forgotten or didn’t follow the original story. By the way, I loved the film. #BestPicture, IMO.
Science editor-in-chief Holden Thorpe gave the day’s first warning about the rise of science in China.
He says he can see it in the papers researchers are trying to get published in the top scientific journal he edits.
"Submissions from China continue to increase, not just in number but in quality, and submissions from the U.S. are going down,” Thorpe said.
He later added: “The atmosphere there (China) is just so much more pro-science than it is here.”
Here is a video.
2010 review of our CAR T grant proposal: patients. Although “incurable” these patients do not warrant early exposure to risky treatments.
2026 Carvykti: Hold my almost 3 billion dollar beer