@KVN_03 Cardiologist here. CPAP is just treating the downstream effects of a problem. Figure out the cause of the Sleep Apnea: enlarged tonsils, enlarged adenoids, large tongue, small jaw etc?? Have your Dr. treat the underlying cause
@jasonryanmd Absence of an RCT isn’t evidence of no benefit. Ppl have a right to understand their own anatomy, and a normal lipid panel doesn’t rule out subclinical disease. Our job is to interpret findings, not gatekeep access to them.
@DrKamleshDarji1 Actually quite the opposite. Residents rarely produce anything meaningful, no one actually cares, and all they remember is your work ethic.
There should be less focus on meaningless publications and moreso on a FEW meaningful contributions to the medical society.
@SamaHoole Every cell eats sugar. PET scans don’t show “cancer eating”..they show cancer eating FASTER than the tissue next to it.
And if you cut carbs, your liver builds glucose from protein. You can’t starve a tumor by skipping toast. Your body is the bakery
@AmmousMD This is why absolute vs relative risk matters.
Yes, small increase in diabetes…mostly in people already on that trajectory.
But the reduction in MI/stroke risk is substantially larger.
Leaving that out is misleading.
@SamaHoole 1. No doctor is quoting “10-year risk” to a 31yo. ASCVD risk calculators start at age 40..
2.LDL is causal in atherosclerosis, not just a “transport vehicle.”
3. “Looking at the wrong number”. LDL-C is literally the most validated biomarker in cardiovascular medicine
@yuripridemd <55 is aggressive without knowing if the calcium is intramural. CAC tells you about burden, not composition. Why not <70 per guideline-directed targets and escalate based on plaque characterization if available?
@sweatystartup Cardiologist here. Most physicians absolutely recommend annual labs. The doc you’re described is an outlier, not the standard. You’re right that people should know their numbers. You’re wrong to frame it like the medical community is against that.
@CaryKelly11@DrSiyabMD You get one life with zero control group. You have no idea what your life looks like without modern medicine…you just know you’re alive to tweet about it
Palantir CTO @ssankar in 2024:
“For $10 billion, @elonmusk put 300 rockets in orbit.”
“For $11 billion the state of California has built 1600ft of elevated rail, with no rail.”
@robertlufkinmd Insulin is a downstream marker of metabolic risk.
LDL/ApoB is a causal driver of atherosclerosis.
We measure what causes the disease and what lowering it has done to prevent events.
@RobGoodall6@confusingbits@CaryKelly11@grok I hear you. The main caution is NNT isn’t a fixed property of a drug; it changes dramatically based on baseline risk + trial duration.
That’s why clinicians focus on risk stratification (ASCVD + CAC) to target therapy where absolute benefit is meaningful.