Priya R. Banerjee

learning how macromolecular phase transitions program cellular functions. interested in single-molecule biophysics, disordered proteins and RNA.

[Priya R. Banerjee @BanerjeeLab_UB]

How do RNAs phase separate without proteins? 💧💧🩸🩸
We are excited to share this story with you (preprint) "RNAs undergo phase transitions with lower critical solution temperatures".

https://t.co/D9h3JNNqjC

A longer thread will follow soon. @gable_wadsworth @PappulabWashU

[Priya R. Banerjee @BanerjeeLab_UB]

New preprint from our lab!

How do condensate material properties encode function? Combining experiments and modeling, we show that condensate interfaces can act as hubs for microtubule (MT) assembly, with MT assembly dynamics tuned by viscoelasticity.

https://t.co/COJKIVSA4A

[brangwynnelab @brangwynnelab]

Wonderful visit to @StJude with great collaborators.

[Priya R. Banerjee @BanerjeeLab_UB]

@I_Alshareedah Congratulations 🍾 Ibraheem

[Priya R. Banerjee @BanerjeeLab_UB]

What physical principles actually govern whether stress granules promote or suppress amyloid formation?

Check out our new preprint led by an outstanding collaborative team comprising our group and Tanja Mittag’s group at St. Jude CRH.

https://t.co/GISYCXJ6pJ

[Priya R. Banerjee @BanerjeeLab_UB]

📢 Abstract deadline Nov 1!

Join us at the FASEB Conference on Biomolecular Phase Transitions (Jan 11–15, 2026, Melbourne, FL), showcasing cutting-edge research on condensates in health & disease, and therapeutic frontiers.

~30% talks from abstracts!

https://t.co/2WAfu2RY1l

[Priya R. Banerjee @BanerjeeLab_UB]

Excited to announce the 2026 FASEB Conference on Phase Transitions in Cellular Signaling & Disease!

An exciting speaker lineup and >30% of talks will be chosen from submitted abstracts.

https://t.co/C7jUMxavkm

📅 Jan 11–15, 2026; 📍 Melbourne, Florida 🌴

[Priya R. Banerjee @BanerjeeLab_UB]

Latest work on RNA condensation from the Banerjee lab, led by a superstar graduate student, Tharun Mahendran.

Biomolecular condensates can enhance RNA percolation, leading to the emergence of multi-phasic RNA condensates.

https://t.co/SyfgJfAvFf

[Taekjip Ha @taekjip]

Check out this tour de force study by Sangwoo Park and his incredible team of collaborators.
Biophysical properties of single nucleosomes are responsible for A and B compartments in cell nucleus.

[ShorterLab @ShorterLab]

DNA binding and mitotic phosphorylation protect polyglutamine proteins from assembly formation: Cell https://t.co/ZssMDPgVfs

[Shekhar lab @sshekhr]

📢Excited to share our new paper in @NaturePhysics : Cooperative hydrodynamics accompany multicellular-like colonial organization in the unicellular ciliate Stentor!

How do single-celled organisms benefit from teamwork? Let’s dive in! #Multicellularity
https://t.co/qtt3HTDjVx?

[Priya R. Banerjee @BanerjeeLab_UB]

Happy to share our new preprint on small molecule mediated inhibition of aging of biomolecular condensates.

[Tharun Selvam Mahendran @tharun_selvam]

In our new preprint, we study the physical aging of biochemically active condensates formed by an engineered Tau protein into disease-linked amyloid fibrils — and investigate whether small molecules can counteract this transition. @BanerjeeLab_UB
https://t.co/7z2JI83D4l
🧵1/3

[Phase Transition Papers @Pha_Tran_Papers]

Tunable metastability of condensates reconciles their dual roles in amyloid fibril formation
https://t.co/nQEKwdrCwt

[Priya R. Banerjee @BanerjeeLab_UB]

This observation led us to investigate the impact of sugar modifications on RNA condensation. We found that 2'-O-methylation (2'-O-Me) negatively regulates RNA condensation and promotes reversibility, suggesting that 2'-O-Me serves as a tunable switch for RNA condensation. 2/2

[Priya R. Banerjee @BanerjeeLab_UB]

New preprint in collaboration with @jerelleaj!! We show that the 2’-OH group of ribose sugar plays a crucial role in RNA condensation, while its absence in DNA inhibits phase separation and percolation, a transition linked to condensate arrest. 1/2

https://t.co/naRSsl0I6f

[brangwynnelab @brangwynnelab]

Excited to see this (cover) article on condensates come out in Scientific American. Nice quotes from me and many folks in the field. https://t.co/mJQICfc8Z4

[The PotoyanGroup @potoyangroup]

In collaboration with @BanerjeeLab_UB, we dive a little deeper into the microscopic interactions and sequence patterns shaping condensate activation energies https://t.co/A2nBb7TZzh. For more context, see also our prior work https://t.co/tba15pwksw

[Kresten Lindorff-Larsen @LindorffLarsen]

Meet the CALVADOS RNA model on bioRxiv or on 🦋

[Serena @sesamedusa]

“I still believe that finding mind lodged in biological matter is the most profound question that physics can pose. And that the breadth of physics is a good base from which to begin.” This is what we believe too at @PRX_Life

[The PotoyanGroup @potoyangroup]

The #APS deadline for abstracts has been extended to Oct 31! This is an excellent venue to showcase your work if you work in computational/experimental cellular biophysics featuring biomolecular condensates. Co-organized together with @hbozhao, Yaojun Zhang, Patrick McCall

[Priya R. Banerjee @BanerjeeLab_UB]

@brangwynnelab @sapinker @HenryLouisGates Congratulations 🎉🎈🎊