The Biosynthetic Pathway to the Pyrroloiminoquinone Marine Natural Product Ammosamide C | Journal of the American Chemical Society @UofIllinois https://t.co/JpM1jbzeqZ
Mycobacterium tuberculosis growth arrest on propionate at acidic pH is suppressed by mutations in phoPR and pyrazinamide treatment https://t.co/Q9jU25E4Jl
Thrilled to share our latest paper now out in @ScienceMagazine 🎉🤩 We investigated a century of plasmid evolution 🧬 and uncovered how they have adapted to the antibiotic era 💊
https://t.co/CuQwlJXlb9
How the twin-arginine translocase (Tat) system manages to transport folded proteins across membranes without any leaks? To answer this fundamental question we solved the first structure of TatB3C3 complex with bound cargo. Please check out new preprint!
https://t.co/962Kj9pt6F
Attending Queenstown Research Week?
Join @CARB_X Chief Scientific Officer Richard Alm, PhD, for his presentation “CARB-X – Accelerating the Development of Novel Products to Tackle AMR.”
📆 Wednesday, September 3
⏰ 3:30 PM NZST
Here’s our latest biosynthetic study on swainsonine, https://t.co/CCC2wYCaQJ — a pathway far more complex than expected and packed with enzymes brimming with synthetic potential. Led by our fantastic postdoc, @shaonan_liu, who will soon be starting his own lab in Shenzhen!
Join @CARB_X Chief Scientific Officer Richard Alm, PhD at a @MTPConnect_AUS panel discussing innovation in antibiotic R&D, sharing insights on translating AMR research into real-world solutions.
📆 Monday, July 14
⏰ 12 – 2 PM ACST
🔗 Register now: https://t.co/v8W93aBytW
A recent @OpenAccessGov piece by Melissa Gong Mitchell of @AMRAlliance highlighted the urgent need to fix the broken antibiotic R&D pipeline and the role of push incentives like @CARB_X in driving early-stage R&D.
🔗 Read more: https://t.co/OEEjrZKnh6
#AMR#StopSuperbugs
Thrilled to share our work that reveals unusual biosynthetic machinery for the core architecture of radarin indole-diterpenoids! Check out the incredibly complex cyclisation chemistry by the noncanonical terpene cyclase RadB.😊
@Ferrier_Inst@J_A_C_S https://t.co/R7IbX31JNQ
Non-Canonical Type II Terpene #Cyclases Deliver Rare Terpenoid Architectures by Rose M. McLellan (@Dr_Rose_Gold), Daniel Berry, Rosannah C. Cameron, and Emily J. Parker at @Ferrier_Inst in @J_A_C_S https://t.co/Efz0EyOkKC