Evaluation of Synthetic GnRH-Analog Peforelin with Regard to Oocyte Differentiation and Follicular Development in C57BL/6J Mice https://t.co/W1F856NBMJ #mdpianimals via @Animals_MDPI
Antinephrin Autoantibody Podocytopathy from @Tobias_B_Huber#RKDSummit#Nephpearls
📌 Antinephrin Autoantibodies are associated with disease
☑️ 69% in active minimal change disease (MCD) pre-treatment
☑️ 90% in active idiopathic nephrotic syndrome pre-treatment
📌 Antinephrin Autoantibodies correlate with disease activity
📌 Antinephrin Autoantibody Titers can be used for therapy guidance
https://t.co/a7sO8JIi41
Biggest medical discoveries of the week (🧵)
1/10
Spinal cord injury triggers activation of T cells, inflammation, and death of neurons
Editing the T cell receptor, using mRNA, suppressed this, and helped recovery from the injury (in mice!)
(Paper: https://t.co/RLgHRoj9XG)
It took more than a DECADE... but finally it’s published!!! It started as a CRAZY idea but after tons of hard work we built it: We hijacked the endogenous secretion systems of Toxoplasma gondii, a brain parasite, to deliver active proteins to neurons 👇
https://t.co/I2j2pAel69
Is forgetting a bug or a feature? Can you delay it and remember longer? Our 🥶COOLEST paper to date (and our most poetic abstract…) Show LOVE ❤️and please SHARE! Thread (1/N)👇
https://t.co/nhe4P2dk7G
Cancer hijacks neurons, integrates with neural circuits to promote growth, and this has become a new target for treatments in clinical trials
https://t.co/A8jyC6u9WG new feature @Nature
Analysis of blood samples from patients with #LongCovid has revealed serum protein changes as the likely culprit. The results show potential biomarkers for diagnosis and could yield insights into treatment.
https://t.co/C6LTQAA7rC
#SciencePerspective: https://t.co/XwGp8nF0zf
For the first time, scientists analysed the connectome for part of the brain in the common octopus involved in long-term memory. Here, they use #ElectronMicroscopy to trace the length of an axon micron by micron. https://t.co/pfkSd1bicH
🏆 Congratulations to Dana Matzek, the 2023 #EPAA3Rs#Refinement Prize winner! 🌟 The Mobile R Pen isn't just impressive; it sets the standard for humane laboratory rabbit housing. Here's to advancements in animal welfare and a commitment to refinement! 🐇🎉
A new Science study showcases the use of optimized human organoids for #CRISPR-based functional screens, paving the way for the identification of additional regulators in human gut physiology and pathophysiology.
📄: https://t.co/KfVpYhAMkU
Pores for messengers: A team led by Markus Sperandio from LMU’s Biomedical Center has identified a molecular mechanism by which #immune cells release pro-inflammatory #alarmins.
https://t.co/1Dscc12qH5
New paper out where we show that podocyte processes are not randomly oriented on glomerular capillaries. Thanks to all the great people who contributed! @LinusButt@amer_rc@HoehneMartin @HBrismar @BernhardScherm1
Check out my interview in @eLife ! ❤️💥We discussed what it’s like to be a scientist on Twitter, making academia jokes, insults, and Michael Eisen @mbeisen 👇👇👇Please share and hopefully enjoy 😅 https://t.co/W5NM2LTAq7
As the search for new and better treatments for #AlzheimersDisease continues, a phase 1 proof-of-concept study evaluating #senolytic therapy breaks new ground.
Read the News & Views from Frank Longo and Stephen Massa @StanfordMed@UCSF
https://t.co/UG1Ok0WiZR