Out today in @Hemasphere_EHA ! We are very pleased to see this collaborative work in print. Here, we leverage cell-free (cf)DNA WGS as an assay for tumor-informed minimal residual disease tracking in smoldering myeloma. #mmsmm (1/n)
https://t.co/lRCmnJoTFY
Overall, the resolution for systemic residual disease augments our current approach and delivers added value despite higher (less deep) LODs. We and other groups will work to improve LODs. (10/n)
@bdermanmd The IKAROS-dependent (IDH2) expansion is interesting, but lets not ignore the near-requisite selection bottleneck from ASCT. Here, 97% had a prior ASCT. Similar for TP53 t-MDS/AML. Other words, in a future with less ASCT, I hope incidence will be lower (regardless IMiD/CELMoD).
So proud of Jerry Soff, MD @SylvesterCancer@UMiamiHealth for leading this study! Romiplostim versus Placebo for Chemotherapy-Induced Thrombocytopenia | New England Journal of Medicine https://t.co/ZhSlRbYeDm
Today the FDA accepts the new drug application (NDA) for Iberdomide in relapsed/ refractory myeloma. In this HealthTree video fro ASH25 IberKRd is being discussed
#MMSM#ASH25#myeloma
https://t.co/4UJlskOmHx
It was a pleasure to write a commentary with @abhip4y on this elegant article by the @MoffittNews team (Mark Meads, Xioahong Zhao, Rachid Baz, and Ken Shain) in @BloodPortfolio.
Original paper: https://t.co/e8FHl7wjt1
Commentary: https://t.co/cSigMlc91z
@SylvesterCancer
We were enthusiastic about the clear demonstration of anti-CD38 biology here, given post-treatment assessments were performed after initiation of Dara monotherapy (i.e., not in combo with the usual suspects aside from steroids).