What are the functional roles of 3D genome organization? In a new preprint led by @_prashantbhat, we demonstrate a critical role for dynamic 3D organization of genomic DNA around nuclear speckles in controlling the efficiency of mRNA splicing.
https://t.co/zWBaXr7jmy
Congratulations to Michael B. Elowitz of @Caltech@ElowitzLab who joins the National Academy of Sciences for his outstanding contributions to synthetic and systems biology. #NAS159
Read more: https://t.co/QF3GoVJrsV #systemsbiology
1/ Excited to share our preprint from @arjunrajlab on clampFISH 2.0: a method for rapid, multiplexed RNA imaging (e.g. 10 genes in 1 million cells in ~1.25 days) @pennbioeng https://t.co/qZOJHhdvKy
If you’ve done conventional single-molecule RNA FISH, you’ll know it is slow…
I am very excited to share the work of @kofi_acheampion and @DylanLSchaff as well as the first pre-print from the lab!! 🥳 -- Multiplexed detection of SARS-CoV-2 genomic and subgenomic RNA using in situ hybridization
https://t.co/39wocJC46o
Excited to share my (first) first author preprint from @arjunrajlab + Twitterless Rajan Jain lab "Cell type determination for cardiac differentiation occurs soon after seeding of human induced pluripotent stem cells" https://t.co/1c9yx8QDrV
Excited to share my (first) first author preprint from @arjunrajlab + Twitterless Rajan Jain lab "Cell type determination for cardiac differentiation occurs soon after seeding of human induced pluripotent stem cells" https://t.co/1c9yx8QDrV
Excited to see our paper finally out! A co-equal collaboration with Alex Sakers (twitterless) in the @LabSeale We sought to identify the cell types involved in making energy burning fat cells around blood vessels.
It is my great pleasure to introduce *Dr.* @laurenbeck131, who just successfully defended her thesis! I have been so lucky to work with her on her awesome organoid constraint work for the past few years. She is brilliant, talented, and has taught me so much about perseverance.
Happy to share our latest work just out at @CellSystemsCP ➡️ https://t.co/1H5xPxunqq. We discovered a single-cell signaling mechanism by which melanoma cells can survive and slowly proliferate despite being targeted with precision anti-cancer drugs RAF/MEK inhibitors (1/6)