Prashant Bhat

Foraging unknown molecular and cell biology to improve human health
M.D. @UCLA👨🏽‍⚕️Ph.D. '23 @Caltech
Incoming Pathology Resident @UCSFPath

[Prashant Bhat @_prashantbhat]

A long sought after hypothesis has been that organizing biomolecules in and around nuclear bodies is essential for functional RNA processing. We now provide direct evidence of this in @Nature for nuclear speckles and mRNA splicing. Check out this thread!

https://t.co/DoXSB7SINt

[Mitch Guttman @mitchguttman]

What are the functional roles of 3D genome organization? Our paper in @Nature led by @_prashantbhat demonstrates how dynamic 3D genome organization around nuclear speckles plays a crucial role in regulating mRNA splicing efficiency. https://t.co/8KwfJHQWTt

[Prashant Bhat @_prashantbhat]

4/2015: First day visiting Caltech
4/2026: Same spot, last day in Pasadena 11 years later!

Kudos to my mom for remembering this picture and wanting to recreate it. Moms know best :)

Also, she wants you to know she didn't age.

@uclacaltechmstp @Caltech @CaltechBBE

[Prashant Bhat @_prashantbhat]

@cavankatenaugh @UCSFPath @uclacaltechmstp @mitchguttman @UCLA_Pathology Thanks Kate!

[Prashant Bhat @_prashantbhat]

I matched to my #1 program at @UCSFPath in their Clinical Pathology/Physician Scientist Program!

Excited to meet my co-residents & colleagues! Kudos to @uclacaltechmstp, @mitchguttman, Zhen Mei, Dave Dawson and many others at @UCLA_Pathology for their support!

SF, here I come!

[Elham Khanafshar, MD, MS @ekhanafshar]

Welcome to the team!
#ucsfpathology

[Prashant Bhat @_prashantbhat]

@UCLA_Pathology @UCSFPath @uclacaltechmstp @mitchguttman Thank you!!

[Prashant Bhat @_prashantbhat]

@bloodgenes @UCSFPath @uclacaltechmstp @mitchguttman @UCLA_Pathology Thanks, Vijay!

[Prashant Bhat @_prashantbhat]

@fiddle @openclaw @OpenAI Cool, thanks for sharing!!

[Prashant Bhat @_prashantbhat]

@inelasticlevi @ACSPublications Wow, congratulations! Love the cover.

[Mitch Guttman @mitchguttman]

Many proteins bind RNA, yet we still don’t know what RNAs most bind because methods map one RBP at a time. In @CellCellPress, with the Jovanovic lab, we describe SPIDR – a method for mapping the RNA binding sites of dozens of RBPs in a single experiment. https://t.co/Zs2Rn35D3s

[brangwynnelab @brangwynnelab]

Excited that our nucleolus mapping paper just came out today in Nature! Truly an amazing study from even more amazing due of @sofiquinodoz & @jiang_lifei w/ @LafontaineLab & Sebastian Klinge and other fantastic co-authors https://t.co/68W7vEHmps

[Prashant Bhat @_prashantbhat]

@Guoming_Gao @UMBiophys Congrats, Guoming!

[Yodai Takei @yodai_takei]

Excited to share our new paper out in @Nature revealing cell-type specific nuclear organization and its link to gene regulation using new spatial multi-omics technologies! https://t.co/0LC2GlEpQs

[Prashant Bhat @_prashantbhat]

@priyabhatpatel @GoNCTD @SDFoodBank Love this!

[Prashant Bhat @_prashantbhat]

@shae_mcl Cool! Can’t wait to dive in. Does filtering for genomic regions by expression influence the predictions?

[Mitch Guttman @mitchguttman]

Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper in @NatureGenet describes ChIP-DIP, a method for genome-wide mapping of hundreds of DNA-protein interactions in a single experiment.

https://t.co/0aINMj2MTu

[Prashant Bhat @_prashantbhat]

@ayushnoori @uclacaltechmstp @HarvardDBMI Thanks Ayush! Looking forward to meeting you!

[Prashant Bhat @_prashantbhat]

Hi! I’ll be speaking at @harvardmed Department of Biomedical Informatics on December 5th about genome organization and splicing/speckles. Thank you to the organizers for the invite! Harvard/MIT/affiliate trainees can RSVP to attend with this link:

https://t.co/crLBGqb5Zf

[Prashant Bhat @_prashantbhat]

@inelasticlevi @doescience Congrats Levi and team!

[Prashant Bhat @_prashantbhat]

@kike411 @NatureComms @MaiteHuarteLab @mikelhernaez Congrats, Kike!