@theliverdoc As clinicians, we should be cautious about overgeneralizing these findings beyond the drugs and endpoints actually studied. Rather than being the final word on the subject, this study serves as an important starting point and provides direction for future, more robust studies.
@theliverdoc Congratulations on publishing this work sir . My concern is that statements such as "it is the same medicine" may overextend the study's findings.
@theliverdoc The study primarily assessed pharmaceutical quality and cost-effectiveness in common drugs such as metformin, amlodipine, atorvastatin and pantoprazole. It did not evaluate bioequivalence, clinical outcomes, or narrow therapeutic index drugs such as tacrolimus, phenytoin, lithium
Bihar !Araria Deputy Collector–Doctor Row Escalates:
Deeuty Collector Slapped doctor during Inspection;
Bihar Health Services Association (BHSA) Issues Ultimatum
#MedTwitter
Just out: Mayo Clinic mSMART Risk Stratification of Myeloma
#EHA25
1/ We recommend and use same high risk cytogenetic definition as the latest IMS/IMWG paper
2/ Primary plasma cell leukemia is high risk myeloma
3/ We define Double-hit high risk myeloma
https://t.co/R4hz7umwEJ
⚠️Not all FSGS is the same!
👉🏻This brilliant flowchart shows 🔍how foot process effacement + nephrotic status guide the diagnostic path.
🚨Think before you immunosuppress!
✅Must-read review for every Nephrologist
#FSGS#Nephrology#MedX
https://t.co/95YdW1yILV
1/Do radiologists sound like they are speaking a different language when they talk about MRI?
T1 shortening what? T2 prolongation who?
Here’s a translation w/an introductory thread to MRI.
🫘✅Advantages of Ambulatory BP monitoring
🎯 Identify masked HTN
🎯Identify White coat HTN
🎯Identify nocturnal dipping
Interesting insights from @WomenNeph_india
Basics of GN (part 2)
Clinical presentation correlates with location of injury & state of GBM
1. Epi/Subepithelial injury=nephrotic
2. GBM breach=RPGN
3. Subendothelial injury:acute/DPGN= nephritic
4. Subendothelial injury: chronic/MPGN & double contour= Nephritic-nephrotic
Brugada Syndrome: A Silent Threat to the Heart 🚨
What is Brugada Syndrome?
A potentially fatal genetic disorder affecting the heart's electrical system, leading to an increased risk of sudden cardiac death—especially during sleep. It is caused by mutations in the SCN5A gene, affecting sodium channel function and cardiac conduction.
Brugada Pattern vs. Brugada Syndrome
👉 Brugada Pattern:
- An incidental ECG finding without symptoms.
- Can be triggered by fever, medications, or electrolyte imbalances.
- Management: Monitor and avoid triggers.
👉 Brugada Syndrome:
- ECG changes + symptoms (syncope, palpitations, sudden cardiac arrest).
- High risk of sudden death, requiring urgent intervention.
- Management: ICD implantation, quinidine therapy.
Types of Brugada ECG Patterns:
1️⃣ Type 1 (Diagnostic): Coved-type ST elevation in V1-V3.
2️⃣ Type 2: Saddleback ST elevation.
3️⃣ Type 3: Features of Type 1 or 2 but less pronounced.
Differential Diagnosis
Brugada pattern can mimic other conditions:
🔍 Right bundle branch block (RBBB)
🔍 Early repolarization
🔍 Acute pericarditis
🔍 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
🔍 Hyperkalemia or electrolyte imbalances
🔍 Ischemic heart disease
🔍 Pectus excavatum (chest wall abnormalities affecting lead placement)
Key Features of Brugada Syndrome:
🩸 Sodium Channelopathy: Autosomal dominant with familial clustering.
⚠️ Symptoms: Syncope, VT, VF, and sudden death during sleep.
🩺 ECG Clues: Coved-type ST elevation + T wave inversion in V1-V3.
Source: @MayoClinic@ClevelandClinic
#Cardiology #BrugadaSyndrome #ECG #SuddenDeath #Arrhythmia #HeartHealth 🫀
Hey #Medicine residents 👋🏼
Time to talk about EOSINOPHILS today!
Not as common a consult as thrombocytopenia & anemia but important nonetheless 🤷🏼
A short 🧵 to touch upon all things eosinophilia 👇🏻
#MedTwitter
Extubation Readiness: A to L Checklist
We're obsessed with safe intubation, but what about taking the tube out?
How do we assess extubation readiness?
Here's my simple, alphabet-based A to L checklist:
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