Bigas/Espinosa Lab

🔬Research Group focused on Stem cells and Cancer at @HMar_research @CarrerasIJC 👩‍🔬👨‍🔬 Dr. Anna Bigas and Dr. Lluís Espinosa working together since 1998

[Bigas/Espinosa Lab @BigSpinLab]

Just finished the 7th NF-KB congress at the @HMRIB Thank you to all participants for fantastic 3 days of great science! And thak you to our sponsors

[Bigas/Espinosa Lab @BigSpinLab]

Thank you Bigas and Espinosa lab for showing tbe lab at prbb open day! Great team!
Gracias a los voluntarios!

[Bigas/Espinosa Lab @BigSpinLab]

The 7th NF-kB International Congress is here!
📅 October 7–9, 2026
📍 Barcelona Biomedical Research Park (PRBB)
Join leading experts to explore the latest advances in signaling, inflammation, and disease.
🔗 Register now and don’t miss it!
#NFKB #BiomedicalResearch #Barcelona

[HMar Research Institute @HMar_research]

🔬Researchers from @HMar_research & @hmarpath have identified a key mechanism behind colon cancer metastasis.
🧬A lack of the IKKα protein enables tumour cells to cluster together & survive during dissemination.
📊@NatureComms.
🗞️More: https://t.co/FTIqlgSfFs
@hospitaldelmar

[Bigas/Espinosa Lab @BigSpinLab]

📣Happy to start the year by sharing our team’s latest work on the development of dormant hematopoietic stem cells (HSCs), now available on bioRxiv: https://t.co/y3jkxm6a9v

We show that a population of dormant HSCs with high regenerative capacity is established in the embryo.

[Bigas/Espinosa Lab @BigSpinLab]

📣Happy to start the year by sharing our team’s latest work on the development of dormant hematopoietic stem cells (HSCs), now available on bioRxiv: https://t.co/y3jkxm6a9v

We show that a population of dormant HSCs with high regenerative capacity is established in the embryo.

[Bigas/Espinosa Lab @BigSpinLab]

Happy to share our minimal fetal-like gene signatures (ColoStem & EpiColoStem) that identify high-risk colorectal tumors in >1,100 patients and are measurable by qPCR in tissue and plasma, enabling patient stratification for future targeted therapies.

https://t.co/euQBOf04TF

[IDIBELL @idibell_cat]

Desxifren els esdeveniments genètics que desencadenarien una leucèmia en pacients d’un trastorn rar: la deficiència en GATA2🧬

L’estudi s’ha fet gràcies a models avançats del trastorn fets pels investigadors, una eina clau en la recerca d'ara endavant

👉 https://t.co/nFCXTZZAnf

[Hospital del Mar @hospitaldelmar]

La Dra. Anna Bigas, investigadora @HMar_research i @CarrerasIJC, s'incorpora com a #editoraassociada a @Dev_journal📰

Està centrada en el camp de la biologia del desenvolupament i malalties associades a processos embrionaris

@Co_Biologists @BigSpinLab

https://t.co/e66Z6mJyKR

[Development @Dev_journal]

We are delighted to welcome Anna Bigas (@BigSpinLab) from Hospital del Mar Research Institute and Josep Carreras Leukemia Research Institute as a new Associate Editor at Development, handling papers on #haematopoiesis, #signalling and #cancer.

https://t.co/QGK39bvOwp

[ESC & iPSC News @ESC_iPSC_News]

Check out this new research from the @BigSpinLab!

The authors found that IκBα accumulates specifically in the chromatin fraction of mPSCs.

📚 More in @eLife: https://t.co/zau5JFap9E

[Science Media Centre España @sciencemedia_es]

🩸Desarrollan modelos de embrión en laboratorio que producen células sanguíneas

🗨️Anna Bigas @BigSpinLab: "Es un trabajo muy preliminar que sugiere que, con las condiciones adecuadas, seremos capaces de obtener muchos tipos celulares"
https://t.co/0XnPWkbDCd

[Bigas/Espinosa Lab @BigSpinLab]

It's always a pleasure to work together!🔬👩‍🔬

[FlorianLab_StemCellAging @Florian_SCaging]

New paper from our lab finally online 🔥. Congrats to the amazing first author 👏🏽 @Fra_Matteini💥, wonderful collaborators Anna Bigas @BigSpinLab and Antonio Del Sol @delSolLab
Stem Cell Aging Team @idibell_cat
👇🏽👇🏽👇🏽
Notch in HSC aging https://t.co/K6JcGzKvaO

[FlorianLab_StemCellAging @Florian_SCaging]

New paper from our lab finally online 🔥. Congrats to the amazing first author 👏🏽 @Fra_Matteini💥, wonderful collaborators Anna Bigas @BigSpinLab and Antonio Del Sol @delSolLab
Stem Cell Aging Team @idibell_cat
👇🏽👇🏽👇🏽
Notch in HSC aging https://t.co/K6JcGzKvaO

[HMar Research Institute @HMar_research]

📢New Workshop on NF-kB: Cell Plasticity and Cancer

📅 Tues 23 Sep
⏰ 9.30 h
📍 Charles Darwin Room

The workshop will feature presentations from a range of distinguished experts in oncology research

ℹ️ https://t.co/6fJY8lhGJi

[Luis G. Palma @luigalpal]

Thrilled to share with you the latest work from my PhD in @BigSpinLab @HMar_research @CarrerasIJC published in @BloodPortfolio

We’ve programmed blood stem cells from PSCs using CRISPRa screen and found a new “bloody” cocktail

#CRISPR #HSCs #StemCells

https://t.co/uuPoD5C0hL

[Bigas/Espinosa Lab @BigSpinLab]

🚨New paper out!🚨
🔬 CRISPRa screening during mesodermal differentiation identifies 7 key genes with HSC induction potential.
🧬 A 7-gene cocktail drives multilineage repopulation and self-renewal from mouse ESCs.
📄 Don’t miss it!
https://t.co/vHQPJ7FxtU

[HMar Research Institute @HMar_research]

🔬 Join us for the next @hmar_research-@UPFbiomed
Seminar!

🗓️15/07 📌Charles Darwin Room

Talks by @bigas_anna @BigSpinLab & @AMartinezArias @icreacommunity

👉https://t.co/NHLo3ABisf

[Bigas/Espinosa Lab @BigSpinLab]

🚀 New paper out! 🔬Discover how IκBα exerts distinct chromatin- and NF-κB-related regulatory functions, and how its chromatin-related activity restores intestinal stem cell function & differentiation 👉https://t.co/EJGECOjfG6

[Josep Carreras Leukaemia Research Institute (IJC) @CarrerasIJC]

💬 "Som més a prop del somni científic de crear sang artificial amb finalitats terapèutiques"🩸

🔬📺 La recerca del @BigSpinLab, a les notícies de @som3cat

➡️ https://t.co/borR3YcpUO