oaat

investment, biotech

[Nature Cell Biology @NatureCellBio]

The LINK-A lncRNA interacts with PIP3 to hyperactivate AKT and confer resistance to AKT inhibitors https://t.co/tqi8pJLqqL

[oaat @BiotechandMore]

RNA splicing is a primary link between genetic variation and disease https://t.co/dZ8JsrFNO8

[oaat @BiotechandMore]

Dual linked LNA AONs for downregulation of gene expression https://t.co/nITaeQz5XD

[Dirk Haussecker @RNAiAnalyst]

$ions' SMA drug nusinersen continues to SHINE. $7.5M from $biib for advancing OLE study in infants+children: https://t.co/2hOng4ZtwO

[Cell Therapy News @celltherapynews]

Therapeutic miRNAs Targeting Huntingtin for Development of Gene Therapy for Huntington's Disease @UniLeiden https://t.co/AfXN4IQWoY

[Igor Ulitsky @IgorUlitsky]

Interesting stuff and an emerging theme consistent with evolution of many lncRNAs - just 5' is important https://t.co/pLy4Db09Ls

[oaat @BiotechandMore]

Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification https://t.co/TLduiOOmYX

[Dirk Haussecker @RNAiAnalyst]

IMO, highest likelihood of 'solving' Alzheimer's from antisense (-->target space+oligo distribution),here ApoE-rel: https://t.co/yxmFRdksb7

[PubNiche @PubNiche]

CRISPR-based method #tracks RNA | eurekalert | Cell .. https://t.co/ddkAXASOWZ

[oaat @BiotechandMore]

Hexose enhances oligonucleotide delivery and exon skipping in dystrophin-deficient mdx mice https://t.co/wVt2QCZXMR

[oaat @BiotechandMore]

Multi-level omics analysis in a murine model of dystrophin loss and therapeutic restoration https://t.co/xjgZXVHeIq

[oaat @BiotechandMore]

Sarepta Therapeutics Announces FDA Advisory Committee Meeting to Review Eteplirsen as a Treatment https://t.co/XqkMToHhBq via @YahooFinance

[Johns Hopkins Medicine @HopkinsMedicine]

A promising, unusual approach to spinal muscular atrophy research ➨ https://t.co/ZwHcTLC8Eh

[oaat @BiotechandMore]

JCI - <i>POPDC1<sup>S201F</sup></i> causes muscular dystrophy and arrhythmia by affecting protein trafficking https://t.co/2296UOSlR4

[oaat @BiotechandMore]

Defective control of pre–messenger RNA splicing in human disease @JCB https://t.co/qhVoHPctmz

[oaat @BiotechandMore]

Nuclear Retention of mRNA in Mammalian Tissues: Cell Reports https://t.co/sNgvgPb6EH

[Genetic Engineering & Biotechnology News @GENbio]

A variant has been engineered that gives #CRISPR-Cas9 system enhanced specificity: https://t.co/D2eWD0KLJI

[Eric Topol @EricTopol]

Discovery of a #genomic modifier that could rescue muscular dystrophy
https://t.co/nhKCnZTGll @CellCellPress

[New York Stem Cell Foundation Research Institute @nyscf]

It's finally time to talk about gene editing @NYTimes @NewYorker & pay respect to Feng Zhang https://t.co/utjVrFyciK