Blake Hill Lab

Interdisciplinary team seeking to understand how proteins regulate mitochondrial homeostasis in healthy and diseased cells

[Shuichi Onami @sonamix]

https://t.co/HLTajPyz5d LIVE around the world! Jan 18(Euro, Africa, America) -19(Asia, Aus, NZ). You can chat directly with bioimage analysis experts in your time zone! Post your question ideally before Jan 11, and they will match you with the best person. https://t.co/axKPOxg9TP

[Journal of Biological Chemistry @jbiolchem]

New in JBC press: "Human Fis1 directly interacts with Drp1 in an evolutionarily conserved manner to promote mitochondrial fission."
Learn more:
https://t.co/WrY9brJcIQ

[Ugo Kelvin Ihenacho @Absolutenivlek]

Pleased to announce that my PhD thesis work in @Blake_Hill_Lab on structural mechanisms governing vertebrate FIS1 function is finally out in JBC. https://t.co/iWp8RERYFu
🧵a thread

[Blake Hill Lab @Blake_Hill_Lab]

Ultimately, our data support a direct Fis1-Drp1 interaction, in which the Fis1 arm may (via a kinetic effect) occlude the binding site. This interaction promotes mitochondrial fission and suggests the yeast and human proteins are more similar than previously thought. (10/10)

[Blake Hill Lab @Blake_Hill_Lab]

New Hill lab publication from @kanolden and @M_Cleland out in @jbiolchem investigating a long-standing question in mitodynamics in which they show that human Fis1 directly interacts with Drp1 to promote mitochondrial fission! https://t.co/WW87xTDn0U

[Blake Hill Lab @Blake_Hill_Lab]

These results suggest reciprocal interactions between the Fis1 arm and conserved surface are important for Drp1 recruitment and mitochondrial fission. (9/10)

[Kelsey Nolden @kanolden]

Excited to share that my thesis work and the latest from @Blake_Hill_Lab in which we found human Fis1 maintains an evolutionarily conserved, direct interaction with Drp1 is now out on JBC! #mitochondria https://t.co/z4dHWKAbr0

[Robert Haase @haesleinhuepf]

I'm now officially hooked on #LLMs for #BioImageAnalysis presuming they will do my job one day. Welcome BIA-Bob! 🔬🖥️🤖
https://t.co/fQibZdiRCh

[NeuroWoodworks @NeuroWoodworks]

Set of #mitochondria now united with their owner Dr @kanolden. Cherry, oak, walnut and padauk woods.

[Kelsey Nolden @kanolden]

Its official (as of a week ago)! So thankful for my experiences in the @Blake_Hill_Lab the last several years and for having @_Blake_Hill as a mentor #PhinisheD #MCWMSTP

[Blake Hill Lab @Blake_Hill_Lab]

Congrats to Dr. Kelsey Nolden on the successful completion of her PhD!! Now time for the celebration!

[Kelsey Nolden @kanolden]

Defending my PhD dissertation tomorrow! DM for Zoom info if interested in attending virtually.

[Kelsey Nolden @kanolden]

Had such a great week at @StJudeResearch learning about their facilities, programs, and ongoing research as well as sharing some of our lab's own research! #StJudeNGSS