Bone & Joint Research

A Gold open access orthopaedics and musculoskeletal research journal edited by Ms Chloe E. H. Scott and published by Bone & Joint. Impact factor: 5.1.

[Bone & Joint Research @BoneJointRes]

Episode now available! 📣

Our newest #AITalks episode focuses on  how to tackle post-traumatic osteoarthritis after  intra-articular fractures using an  immunoregenerative approach.

Catch the full findings below!

#Podcast #Fracture #BJR

https://t.co/QPB6Qj3dlh

[Bone & Joint Research @BoneJointRes]

In conclusion, in this study we demonstrated that hBMSC-Exos and hADSC-Exos have similar microRNA profiles but are largely different from hiPSC-Exos.

#BJR #StemCells #Research #FOAMed

https://t.co/UO8n5Vwbls

[Bone & Joint Research @BoneJointRes]

This study investigated the cellular and molecular mechanisms by which diabetes mellitus exacerbates osteoarthritis, through multiomics analysis of synovium and cartilage from patients with both conditions.

#Diabetes #Osteoarthritis #BJR #OpenAccess

https://t.co/UhRFjq33S2

[Bone & Joint Research @BoneJointRes]

In this study we compared infection clearance and bone healing in early and delayed fracture-related infection treated with debridement, antibiotics, and implant retention in a rabbit model.

#BJR #Fracture #Infection #OrthoTwitter

https://t.co/Q2iN4tPZKN

[Bone & Joint Research @BoneJointRes]

This article provides an introduction to important aspects of the design process for orthopaedic implants.

#BJR #OrthoTwitter #Surgery #Biomechanics

https://t.co/S9biKAylXk

[Bone & Joint Research @BoneJointRes]

"... treatments impacted cartilage over time".

This week, we spotlight a study that presents promising avenues for treating post-traumatic #osteoarthritis with an immunoregenerative approach, while highlighting the need for further research!

#BJR #Ortho

https://t.co/iNlse6A6Ih

[Bone & Joint Research @BoneJointRes]

The aim of this study was to determine the fracture haematoma proteome after multiple trauma using label-free proteomics, comparing two different fracture treatment strategies.

#BJR #Fracture #Trauma #Surgery #OrthoTwitter

https://t.co/3NMx07JVL7

[Bone & Joint Research @BoneJointRes]

Proximal medial tibial sclerosis severity demonstrates a clear dose-dependent relationship with bone resorption risk following total knee arthroplasty.

#BJR #KneeArthroplasty #Surgery #Research

https://t.co/QDyuErLqCC

[Bone & Joint Research @BoneJointRes]

At 28 days, Adenosine, lidocaine, and Mg2+ therapy reduces inflammation, augments tissue repair patterns, and improves joint function in a sex-specific manner. The study supports transition to human safety trials.

#BJR #Knee #ACL #Inflammation #Surgery

https://t.co/q90Y1xlL8s

[The Bone & Joint Journal @BoneJointJ]

🧠 Revise for your exams now | 🗺️ Gain knowledge for life

BJJ LIFE is more than a revision tool; it's been designed to test your thinking beyond basic facts, and impart clinically relevant knowledge that will stay with you for life.

#FRCS #CPD #Ortho

https://t.co/OGOxgan2B7

[Bone & Joint Research @BoneJointRes]

Vibratory implant insertion may reduce the risk of fractures due to excessive impaction forces by decreasing the impaction force.

#BJR #Fracture #Surgery #OrthoTwitter

https://t.co/34IobFH8jO

[Bone & Joint Research @BoneJointRes]

Naringin could promote angiogenesis of the induced membrane and the mineralization of bone grafts in the later stage in a dose-dependent manner.

#BoneGraft #BoneDefect #Orthopedics #OrthoResearch

https://t.co/VROMlTsrEn

[Bone & Joint Research @BoneJointRes]

Voriconazole-loaded microbubbles represent a promising adjunctive therapy for combating recalcitrant fungal biofilm infection.

#Biofilm #Infection #Orthopedics #BJR

https://t.co/pWhKwNMGUp

[Bone & Joint Research @BoneJointRes]

Based on our results, a single dose of the combination of phages and gentamicin is sufficient to prevent a haematogenous S. aureus implant-related infection, whereas gentamicin needs to be administered daily for the same effect.

#BJR #Infection #Research

https://t.co/MufpreApuJ

[Bone & Joint Research @BoneJointRes]

rhPAPP-A2-induced signal transducer and STAT3 phosphorylation were associated with bone formation and reduced IGF1-binding protein expression specifically in females.

#Orthopedics #Research #BoneGrowth

https://t.co/ZkAdkcRZEl

[Bone & Joint Research @BoneJointRes]

Kaempferol exhibited inhibition of ferroptosis resistance, highlighting its promise as a therapeutic agent for rheumatoid arthritis.

#Arthritis #Orthopedics #Research #Surgery #BJR #OA

https://t.co/2AlRq4JyEP

[Bone & Joint Research @BoneJointRes]

This study provides evidence that OX40L monoclonal antibody is a potential therapeutic target for temporomandibular joint osteoarthritis.

Read the full paper today!

#Osteoarthritis #Joint #BJR #OpenAccess

https://t.co/SdjbTO8XPy

[Bone & Joint Research @BoneJointRes]

We explored whether inflammatory biomarkers in blood and cerebrospinal fluid were associated with clinical outcome, and baseline pain or disability, 12 months after THA.

#Hip #Arthroplasty #Inflammation #Patients #BJR

https://t.co/Vf0F3aJgg6

[Bone & Joint Research @BoneJointRes]

The findings suggest that a thinner patella may lead to improved short-term outcomes, such as reduced patellofemoral contact forces and increased joint range of motion, which could contribute to early patient satisfaction.

#Patellar #Knee #Orthopedics

https://t.co/LN6hHrwkT8

[Bone & Joint Research @BoneJointRes]

This study examined the relationship between obesity and osteoporosis, aiming to identify shared genetic markers & molecular mechanisms to facilitate the development of therapies that target both conditions simultaneously.

#MachineLearning #Obesity #BJR

https://t.co/HgybUp90Rg