Brice Liesveld

🚀 Tech Explorer | 📽️ Film Producer/Writer | 💵 Capital Allocation
👋 Looking to connect with people in Tech, Film, & Capital Markets -Angels, VC, LPs, GPs, PE

[Brice Liesveld @Brice]

https://t.co/QFzn5AApRu

[Brice Liesveld @Brice]

@JimPethokoukis Some of this is information warfare artificially shaping public opinion. It’s coming from all sides. Need to put the breaks on that asap.

[Derek Thompson @DKThomp]

This has quietly been a miracle month in medicine.

In the last 5 weeks we’ve got news on:

- retatrutide, the triple agonist GLP-1 from Lilly, basically melting fat and body-wide inflammation at record levels
- RevMed’s new pancreatic cancer drug showing unprecedented abilities to extend life
- small trial of a one-and-done PCSK9 gene editing therapy for slashing LDL cholesterol
- Mayo’s AI-assisted radiology showing vastly improved cancer detection
- this new therapy for metastatic solid tumors

This stuff is at varying levels of evidence. Retatrutide is ~100% on its way, other stuff needs more clinical trial data. But put it together and we’re maybe on the verge of majorly reducing the mortality of heart disease and cancer, the two leading causes of death in America.

[Brice Liesveld @Brice]

@dhavalgarg @ayeejuju Even with outcomes, there is an assumption that a binary result is possible.

Play the same game with no aces in the deck.

[Brice Liesveld @Brice]

@Molson_Hart What that area do, a couple billion in VC raises in 2025? Even at like 1/50th the size of Austin?

[Morgan Barrett @MorganBarrettX]

Was trying to catch up with Ricky Medina from AnySignal at El Segundo Tech Breakfast Club but then Jacques Sisteron (Upfront VC) crashed the conversation

If you're a founder and considering setting up shop in El Segundo - get it touch. Everywhere else in California is red tape. In El Segundo it's the red carpet

[Brice Liesveld @Brice]

@uu5ua That photo-quality difference, though... yeesh.

[Brice Liesveld @Brice]

@PalmerLuckey @AOC Most of it is legacy framing that's stuck around from the days of the textile manufacturers, railroad, oil, and coal barons.

But there is also a bit of truth. It's hard to look past the fact that millions of Americans have full-time jobs & still rely on gov assistance.

[Jared West @jared_western]

Coming soon to El Segundo!

[Brice Liesveld @Brice]

X is shutting down Communities on May 6.

I just reserved my spot in the new home for #buildinpublic.

Come with me: https://t.co/WCc9CRNR54

[Brice Liesveld @Brice]

@elonmusk Interesting, I wonder what constraint they're seeing in China that would drive this investment. They don't have the regulatory or power generation buildout issues we have in the states.

[Brice Liesveld @Brice]

@ClaudeDevs need better documentation on HIPPA features. Initial inquires to sales are not immediately helpful.

[Mayor Matt Mahan @MattMahanSJ]

California has increased spending by 75% in six years.

Are your bills 75% cheaper?
Are our schools 75% better?

No.

Because the problem isn’t how much we spend — it’s how we spend it. And I’ll only spend taxpayer dollars on policies that actually make people’s lives better.

Plan out tomorrow. Thanks for the conversation @friedberg!

[Brice Liesveld @Brice]

@HyperAICapital Power draw is probably a better indicator of what’s happening on the ground. Just how big are some of these?

In CA for example there are 5 major data centers being built targeting ~ .5 TW of useable power.

[Brice Liesveld @Brice]

🤔

[travis kalanick @travisk]

Atoms.

https://t.co/nbCnIkI3RD

[Brice Liesveld @Brice]

@vponamariov Does this have SEO implications?

[Brice Liesveld @Brice]

@BarjiYT Its called z-depth for a reason. 😃

[Brice Liesveld @Brice]

@mattparlmer lol, I don’t think we can be friends anymore.

[Brice Liesveld @Brice]

@balajis Unless there is some underlying black box architectural change under the hood, open source will eventually dominate.

[Brice Liesveld @Brice]

@chamath @TimKoltek If only we didn’t kneecap the entire US industry the last few years. 🤨

[SciTech Girl @scitechgirl]

🚨 DIABETES CURE… OR THE BEGINNING OF A MEDICAL REVOLUTION?

For over a century, diabetes has meant daily injections, constant monitoring, and a lifetime of management. But now, scientists in China and researchers at Vertex Pharmaceuticals in the United States have done something shocking, they used stem cells to create new insulin-producing cells and transplanted them into real patients.

And here’s the twist…
Some people with Type 1 diabetes started making their own insulin again.
No pump. No syringe. Just living cells doing their job. It’s not a full cure yet. Trials are still small, and long-term results are unknown. But for the first time, medicine isn’t just managing diabetes, it’s trying to rebuild the pancreas itself.
Science fiction?
Not anymore..