Brönstrup Lab

Chemical Biology | Antinfectives Screen | Targeted Drug Conjugates | Metabolomics | Mode-of-Action Studies @Helmholtz_HZI @LeibnizUni @DZIF

[DZIF (inaktiv) @DZIF_]

🚀 Gemeinsamer Erfolg in der KI-Forschung! 🇩🇪🇫🇷 Ein deutsch-französisches Team, darunter DZIF-Wissenschaftler, erhält einen ERC Synergy Grant über 11 Mio. Euro.

Ziel: Entwicklung eines KI-gestützten Ansatzes für die Suche nach neuen Antibiotika: https://t.co/ITb6H54SNv
#ERCSyG

[Helmholtz-Zentrum für Infektionsforschung –inaktiv @Helmholtz_HZI]

The HZI is looking for game changers in infection research and hiring Junior Research / Technology / Clinician-Scientist Group Leaders (with W1-professorship & tenure options). Join our program #HUMAN and study the complex interplay of humans & microbes!
https://t.co/eslC4Twm7H

[Brönstrup Lab @BronstrupLab]

Our study on the last resort antibiotic colistin was just accepted by Angew Chem. (https://t.co/hm2E5SH0cE). We reduce its renal cell toxicity by a two-component strategy and bioorthogonal chemistry.
#chemicalbiology #antibiotics @helmholtz_hzi @_dzif @UniHannover

[SchulzLab @LabSchulz]

Volatile salinilactones, produced by the bacterium Salinispora, target disulfide-isomerases. See https://t.co/6SDUIMEkFw in Advanced Science, by K. Jerye et al. of the @BronstrupLab. This is one of the first studies describing how bacterial volatiles act.

[Brönstrup Lab @BronstrupLab]

(2) Major topics (novel antiinfectives, computational methods, new concepts, two free-of-charge workshops) introduced by international speaker panel.
@UniHannover #chemicalbiology #antibiotics #DrugDiscovery @helmholtz_hzi @_dzif @UniHannover @tuBraunschweig @EuroMedChem

[Brönstrup Lab @BronstrupLab]

Full program available, few days and <40 seats left for registration: 3rd Helmholtz Drug Discovery conference HDDC 2023 on May 15/16 in Braunschweig, Germany. https://t.co/MAM4yQiA4B (1)

[Zach Reitz @ZachReitzPhD]

@BronstrupLab correct link:
https://t.co/SIheq25jBe

[Brönstrup Lab @BronstrupLab]

(2) @UniHannover #chemicalbiology #antibiotics #DrugDiscovery @helmholtz_hzi @_dzif @EuroMedChem

[Brönstrup Lab @BronstrupLab]

Our paper on siderophore conjugation with cleavable linkers to boost the potency of RNAP inhibitors has just appeared in Chemical Science (https://t.co/KSbmaIJQrw). Thanks a lot to Carsten, Hazel, Anna et al. for the great work! (1)

[Brönstrup Lab @BronstrupLab]

(2) Major topics (novel antiinfectives, computational methods, new concepts, two free-of-charge workshops) introduced by international speaker panel.
@UniHannover #chemicalbiology #antibiotics #DrugDiscovery @helmholtz_hzi @_dzif @UniHannover @tuBraunschweig @EuroMedChem

[Brönstrup Lab @BronstrupLab]

Abstract/talk submission closes this weekend: Please register for 3rdHelmholtz Drug Discovery conference HDDC 2023 on May 15/16 in Braunschweig, Germany. https://t.co/MAM4yQiA4B (1)

[Brönstrup Lab @BronstrupLab]

(2) Low registration fees. Please submit abstracts for short talks/posters. #chemicalbiology #antibiotics @helmholtz_hzi @_dzif @UniHannover

[Brönstrup Lab @BronstrupLab]

We announce the 3rd Helmholtz Drug Discovery conference HDDC 2023 on May 15/16 in Braunschweig, Germany. Major topics (novel antiinfectives, computational methods, novel concepts, success stories) introduced by international speaker panel. https://t.co/ulG0c7xaEp

[Brönstrup Lab @BronstrupLab]

We are happy to enter the second round of the SPRIND challenge for novel antivirals. Thanks also to our partners, the Hilgenfeld lab, @biotechne and the Kikkert lab @LUMC_Leiden.

[Helmholtz-Zentrum für Infektionsforschung –inaktiv @Helmholtz_HZI]

In einer @SPRIND-Challenge verfolgen Forscher:innen seit dem letzten Jahr innovative Ansätze für breitwirksame antivirale #Wirkstoffe. Sechs Teams, darunter drei mit HZI-Beteiligung, werden nun für die zweite Phase mit je 1,5 Millionen Euro gefördert. 1/2
https://t.co/Ie8GRLLKnl

[ChemEurJ: Chemistry - A European Journal @ChemEurJ]

Optical modulation of antibiotic resistance by photoswitchable cystobactamids (M. Bronstrup et al.) @BronstrupLab https://t.co/OYPwArW3Kt

[Brönstrup Lab @BronstrupLab]

@DirkTrauner Lieber Dirk, herzlichen Glückwunsch und alles Gute!

[Brönstrup Lab @BronstrupLab]

@jcslab @Helmholtz_HZI Dear Jessica, thanks a lot for your lecture and the fruitful discussions with us!

[Brönstrup Lab @BronstrupLab]

@e_boros @Helmholtz_HZI @UniHannover Dear Eszter, thanks for the feedback!We also follow and like your work. Best regards, Mark

[Brönstrup Lab @BronstrupLab]

Our joint paper with Doron Shabat on enzyme-activated, chemiluminescent siderophore-dioxetane probes for highly sensitive bacterial pathogen detection has been published in Angew Chem: https://t.co/pPpmxp1Csk
#chemicalbiology #antibiotics @helmholtz_hzi @_dzif @UniHannover