Check out the MICrONS Explorer - a virtual observatory of the cortex: https://t.co/fo4VHGB607
This #OpenScience data portal includes #ElectronMicroscopy based reconstructions of cortical circuitry from mouse visual cortex.
The brain as it's never been seen before.
Last year, scientists created the largest wiring diagram and functional map of a mammal brain to date.
#BrainAwarenessWeek@dana_fdn
It was my first foray into an environment where human audiological and psychoacoustic research are at the forefront, and I’m elated to have been exposed to cutting-edge work that has immediate clinical potential.
Grateful for the opportunity to present the human auditory neuroscience work I’ve been doing alongside my thesis, where we dug into electrophysiology methods to better characterize subclinical hearing loss and a potential pharmacological therapeutic for young adults with tinnitus
Yes! And when neurons (or networks) carry history and change their responses based on a combination of history and input, that is itself a form of prediction.
Interesting study discerning interneuron types by Neuropixels waveforms alone (after training a ML algorithm with optotagging), and functional assessment of interneuron class function with optogenetics (which is independent of Neuropixels)
https://t.co/368n5gg1ta
Fascinating video showing glutamate lighting up as it’s released in synapses, visualizing the neurotransmitters of the brain, made possible with the fluorescent indicator protein iGluSnFR3.
📽: Allen Institute for Neural Dynamics
pretty interesting findings from @ArielleLBaker. Extra-telencephalic neurons with apparently minimal thalamic input, and pathway specific neuromodulation of cortical afferents. Obvious implications for broader understanding of cortical circuits here.
Wireless battery less unsupervised Optogenetic stimulation of an aversive pathway. Every time the animal enter the open arm they receive 5Hz still without any latency due to Bluetooth or Camera TTL. Animals are highly habituated to the elevated plus maze ... 2DNEURO
Just had an R21 not discussed.
Shame, thought it was fun.
Oh well.
Moving on.
(I’m actually a little concerned as to how detached I am. Sure it would have been better to get it, but I don’t feel upset anymore.)
(Plz repost)
I’ve been receiving some good news lately and will be hiring at all levels to expand the lab. Please get in contact if you are interested in reinforcement learning, neural plasticity, circuit dynamics, and/or hearing rehabilitation.
pierre.apostolides @ umich .edu
In an unprecedented move, the US National Institutes of Health has begun mass terminations of research grants that fund active scientific projects because they no longer meet “agency priorities”.
https://t.co/ALQlFtfuVd
New trend for this year?
#Absolute_Neurophysiology
This year, I'll post classic neurophysiology stories you might not have ever heard of, but probably inform a lot about how we think about 2020s neuro...
We start with the coolest patch clamp figure, maybe ever...
In a country where the future of science as we know it is uncertain, I firmly believe that hearing research is in good hands, and that we will ultimately adapt and overcome.
It’s intriguing gaining familiarity with what other pioneers in the field are working on and witnessing the long-term progression of their research. Additionally, this ARO was uniquely situated right down the road in Orlando, FL, which was quite surreal.