15 years ago, I placed a health bet:
Low-to-no carb diet + MetCon-style workouts + 18-hour daily intermittent fasting, with MetCons done at the 12-15 hour mark of the fast.
At age 62 (5'11.5", 163 lbs), after 15 consistent years, here are my latest labs and metrics across the board.
Metabolic & Body Comp:
- BP: 115/65
- Body fat: 9%
- Triglycerides: 65
- HDL: 65.6
- Fasting glucose: 60
- HbA1c: 5.5
- Total cholesterol: 221
- LDL: 142
- VLDL: 13
- TyG index: 7.58
- VO2 max: 50
- 10-sec Assault AirBike sprint: 1076 watts
What happened next?
Liver labs:
- AST: 33
- ALT: 34
- GGT: 13 (very low)
- ALP: 64
- Albumin: 4.4
- Globulin: 2.1
- Total protein: 6.5
All solid and optimized. Especially that low GGT after years of fasted intense training — liver looks happy.
Kidney function:
- Creatinine: 1 mg/dL
- eGFR (Mayo): 101.56 mL/min/1.73m²
- Urine protein: 1
- Urine creatinine: 82
- Urine protein/creatinine 0.012
- Urine RBC: 0
- Urine WBC: 0
- Urine glucose: 0
Excellent filtration, no spillover, no red flags. Kidneys staying strong.
Heart marker:
- NT-proBNP: 73 pg/mL
Very low and healthy level for a 62-year-old male — excellent sign of good cardiac function and low strain.
Oncology markers:
- PSA: 0.76 ng/mL
- CEA: 1.4 ng/mL
Both nicely low and well within normal ranges for my age. Clean bill here.
These are the receipts after 15 years. I was honestly surprised at how clean everything turned out. The real story which gets very little attention is why it happened. Any thoughts?
Meanwhile, I’ll drop the “why” thread in a few days. It’s where it gets interesting. Stay tuned.
@stringerbell99@SBakerMD I guess the point I’m trying to make here is at 63 my organs show no signs of the ravages of a AGEs. Endogenous or preformed and the only thing I can think of as to why is this protocol driven by intense cellular recycling.
I get it. Agree it’s a management system. After figuring out what happend to me I’ve concluded we have three what I call bio - software settings. The first is to have elite insulin sensitivity. This is by far the most important setting we have. Second is to be as metabolically flexible as you can. Third is to allow your innate cellular cleaning program to run flawlessly. This is our design. It’s a fast- hunt -feast protocol that has served me very well, although unsuspectedly like I said before, I didn’t set out to make all this happen to me, but everything kind of fell in place. Particularly the 18 hour daily fast with a metabolic conditioning workout at the 12 to 15 hour mark.
@stringerbell99@SBakerMD Autophagy in the context of very low to no carb inputs and strong AMPK signaling in the absence of mTOR and insulin. In other words fasted training. This creates an incredibly strong cellular recycling/cleaning.
@bigfatsurprise Maybe it’s that way so you can design narratives around what you want UPF to represent. Somewhat like going from global warming to climate change. With climate change, I can put any narrative I want around it.
@stringerbell99@SBakerMD Maybe. The problem is they (carnivores or my physiology) aren’t studied. We study glucose dependent populations. They form both endogenous and dAGEs. Researchers extrapolate their (glucose dependent) results on to people like me, whom, again, they don’t study.
Hey, don’t go there. That’s not at all why. I don’t provide the materials for glycation. if you go to my profile and look at the pin tweet run that through any AI model. My organs are decades younger than my age and this wasn’t by design. I had no idea what was happening to me for 15 years. as it turns out (which means unplanned) by not providing glycation for materials to make AGEs and doing high intensity metabolic conditioning in the fastest state, I’ve been getting this industrial strength, cellular recycling at least four times a week. Lighter cellular recycling the remaining days of the week. That’s ~5200 cycles of cellular recycling/cleaning that has cleared out those dietary AGEs. This is not something that I intended to happen, but when you reverse engineer what has happened to me, it’s the intense autophagy and lack of glycation that has driven my results. The problem is science doesn’t study people with my physiology.
@stringerbell99@SBakerMD Sure. Grilled meat. I don’t worry about dAGEs, and I’ve consumed thousands of pounds of various grilled meats. Any guess as to why?
Well coach, 15 years ago I made a health bet:
Low-to-no carb diet + MetCon-style workouts + 18-hour daily intermittent fasting, with MetCons done at the 12-15 hour mark of the fast.
15 years later at age 62 (5'11.5", 163 lbs), here are my latest labs and metrics across the board. Run them through any AI model.
Metabolic & Body Comp:
- BP: 115/65
- Body fat: 9%
- Triglycerides: 65
- HDL: 65.6
- Fasting glucose: 60
- HbA1c: 5.5
- Total cholesterol: 221
- LDL: 142
- VLDL: 13
- TyG index: 7.58
- VO2 max: 50
- 10-sec Assault AirBike sprint: 1076 watts
Our 3 bio-software settings
Elite insulin sensitivity
Elite metabolic flexibility
Elite Fitness
Liver labs:
- AST: 33
- ALT: 34
- GGT: 13 (very low)
- ALP: 64
- Albumin: 4.4
- Globulin: 2.1
- Total protein: 6.5
All solid and optimized. Especially that low GGT after years of fasted intense training — liver looks happy and youthful.
Kidney function:
- Creatinine: 1 mg/dL
- eGFR (Mayo): 101.56 mL/min/1.73m²
- Urine protein: 1
- Urine creatinine: 82
- Urine protein/creatinine 0.012
- Urine RBC: 0
- Urine WBC: 0
- Urine glucose: 0
Excellent filtration, no spillover, no red flags. Kidneys staying youthful and strong.
Heart marker:
- NT-proBNP: 73 pg/mL
Very low and healthy level for a 62-year-old male — excellent sign of good cardiac function and low strain.
Oncology markers:
- PSA: 0.76 ng/mL
- CEA: 1.4 ng/mL
Both nicely low and well within normal ranges for my age. Clean bill here.
These are the receipts after 15 years. Reverse engineering revealed, as it turns out, it’s the lack of glycation and super charged AMPK signaling via the fasted MetCons created industrial strength autophagy/mitophagy and ketone signaling resulting in organ health decades younger than my chronological age. Autophagy is incredibly important
@InformedMama1@SBakerMD Metabolic conditioning. These are high intensity workouts that simultaneously work muscles and cardio. Very potent and effective. They build strength and fitness capacity. Let me know if you would like to know more.
Years ago, I was Gambel’s quail hunting, just north of Tucson. My German shorthair, Emmy was tracking some quail. Lot of stop and go pointing. I noticed to my right a Harris Hawk was following and perching on Mesquite trees as we proceeded down the wash. Eventually a quail held and we had a nice solid point. I walked into flush the bird and up it goes and I tag it. Right over my head swooping down is that Harris Hawk, racing Emmy to the quail. It swooped down and back up right as Emmy got to it. Couldn’t find the bird. I think the Harris hawk got it. It was wild scene