Matt Wilson

[Matt Wilson @stringerbell99]

How you you explain the two charts I posted? One that shows a nearly perfect linear correlation between lifetime high/low LDL and heart disease risk and the other shows 100 people with high LDL and no other risk factors (including inflammation) and their 1 year plaque progression. 85% showed some level of plaque progression. 21% had rapid plaque progression.

[Matt Wilson @stringerbell99]

@OpossumsVa @JeremyWGaddy @RobertKennedyJc I just showed you the largest meta analysis ever done on the subject and statin users get dementia less often than non users. They don’t cause dementia, they protect against it.

[Matt Wilson @stringerbell99]

@formfireglass @WellnessWisdomm Also worth noting that your body contains around 150g of cholesterol. LDL carries 2-3g of it. Low LDL does not equal low cholesterol availability to the body. It’s mostly excess that isn’t being used and the liver is not clearing efficiently.

[Matt Wilson @stringerbell99]

You have to understand why that is. Observational studies only find associations, not causation. Many chronic diseases cause low LDL. Cancer, liver and kidney disease, chronic infections and malnutrition/frailty commonly seen in the elderly all cause significant drops in LDL. It’s the underlying illness that causes the increased mortality in these studies. People with genetically low LDL live longer than average.

[Matt Wilson @stringerbell99]

It does not. Dementia is caused by an impaired ability to rid the brain of cellular waste leading to tau tangles and amyloid plaque. It’s mostly genetic, but lifestyle factors also play a significant role. High LDL is one of the risk factors, and statins reduce risk. https://t.co/qaSiQ7hxPv

[Matt Wilson @stringerbell99]

@Tweety4real @DrStephenHussey Here’s the one year plaque progression for people with optimal metabolic markers and no other risk factors except high LDL. Everything over 1 PAV qualifies as rapid plaque progression.

[Matt Wilson @stringerbell99]

@Tweety4real @DrStephenHussey “LDL is not a risk factor for plaque”. So you think it’s just a coincidence that people with genetically low LDL have much lower risk of heart disease and people with genetically higher LDL get it more commonly?

[Matt Wilson @stringerbell99]

@Tweety4real @DrStephenHussey @grok can you summarize the evidence from IVUS studies of intensive lipid lowering and plaque regression/progression?

[Matt Wilson @stringerbell99]

@Tweety4real @DrStephenHussey No one does that because insurance won’t cover it. People are free to do that on their own if they like.

[Matt Wilson @stringerbell99]

@Tweety4real @DrStephenHussey What do you think statins do? What would you blame statins for? Do you think they increase cardiovascular events or something?

[Matt Wilson @stringerbell99]

@OpossumsVa @RobertKennedyJc Jesus, no wonder you’re so hopelessly lost. You think Valorie is a doctor. 🤦‍♂️

[Matt Wilson @stringerbell99]

You’re just retarded. Every study was a publicly funded observational study that has no goal other than to track large numbers of people over long periods of time so researchers can use that data to find associations. In this case, analysis of 7 million people found statin users get all forms of dementia 15-20% less frequently than non users. Zero pharma funding.

[Matt Wilson @stringerbell99]

@OpossumsVa @RobertKennedyJc No idea where you get this nonsense. Statins reduce the risk of all forms of dementia. Also, your brain makes all of its own cholesterol. It doesn’t get it from your blood, and dementia isn’t caused by low brain cholesterol. https://t.co/glI3F0OXEp

[Matt Wilson @stringerbell99]

His normal LDL before keto was 90. He was trying to show that LDL sometimes goes up a lot on keto because the liver has to make more lipoproteins to transport triglycerides, since the body is running on fat. The Oreos gave him glucose back to use as fuel and returned his LDL closer to his baseline than statins. This is because his high cholesterol is caused by his ketogenic diet.

[Matt Wilson @stringerbell99]

@AmericanAFRose @RobertKennedyJc Everything over 1 PAV is classified as rapid plaque progression FYI.

[Matt Wilson @stringerbell99]

@AmericanAFRose @RobertKennedyJc Don’t forget to check their actual data too, rather than just their spin.

[Matt Wilson @stringerbell99]

@RobertKennedyJc “A grifter with diet induced LDL over 500 made another click bait video.” FIFY

[Matt Wilson @stringerbell99]

@KeithBa22086886 @RobertKennedyJc Low cholesterol doesn’t starve the brain. Your brain makes all of its own cholesterol. It doesn’t get it from your blood.

[Matt Wilson @stringerbell99]

There’s no point waiting until you have cardiovascular disease to start lowering risk. Yes, people with an LDL of 30 have plaque regression. They don’t grow plaque. Anyone with an LDL under 30 has it that low because they’re on intensive lipid lowering therapy because they have existing cardiovascular disease.

[Matt Wilson @stringerbell99]

@Tweety4real @DrStephenHussey Statins reduce cardiovascular risk, they don’t eliminate it. Once you have plaque, you’re at risk for a heart attack or stroke.