CBU

Computational Biology Unit led by Prof. Paolo Provero
Neurosciences Dept. at @unito
Tweets are from lab members.

[CBU @CBUuniTo]

This was a team effort spearheaded by our Roberta and Alessandro here at @unito together with @AdelineMorez, Luca Pagani from @DiBio_UniPD & @emiliahsc , big thanks to everyone✨

[CBU @CBUuniTo]

New preprint out: Effects of introgressed Neanderthal alleles on present-day brain morphology! 🧬🧠 using 370 phenotypes derived from ~40k brain MRIs we found a textbook neanderthal-mediated GWAS hit at DAAM1, Neanderthal burden associations and more https://t.co/XbGKR5ptnG

[CBU @CBUuniTo]

New pre-print out! 🎉 With Mathilde + team we traced spatio-temporal shifts in genetically regulated #transcription across 10,000 years of Western Eurasia, fine-mapping regulatory features targeted by #selection! 👉 https://t.co/ihS4OoBats ! #popgen #genomics

[CBU @CBUuniTo]

Polygenic and developmental profiles of autism differ by age at diagnosis

https://t.co/dySY2esKqE

[CBU @CBUuniTo]

Multiancestry brain pQTL fine-mapping and integration with genome-wide association studies of 21 neurologic and psychiatric conditions
https://t.co/N394FPqLRl

[CBU @CBUuniTo]

https://t.co/2MLqGgaVxc

[CBU @CBUuniTo]

Multiple overlapping binding sites determine transcription factor occupancy

https://t.co/MPpJBM0uJJ

[CBU @CBUuniTo]

https://t.co/HO3tdSaUSg

[CBU @CBUuniTo]

https://t.co/vOwSRQfcfm

[CBU @CBUuniTo]

Endogenous fine-mapping and prioritization of functional regulatory elements in complex genetic loci

https://t.co/jabIyNhJ3q

[CBU @CBUuniTo]

The Importance of Regulatory Network Structure for Complex Trait Heritability and Evolution
https://t.co/t3PYJCaEwa

[CBU @CBUuniTo]

Whole-genome sequencing of 490,640 UK Biobank participants
https://t.co/RLdEtyrR0h

[CBU @CBUuniTo]

https://t.co/jGAbNjyRbm

[CBU @CBUuniTo]

Single-cell eQTL mapping of human endogenous retroviruses reveals cell type-specific genetic regulation in autoimmune diseases
https://t.co/IraqNNEJOq

[CBU @CBUuniTo]

Towards improved fine-mapping of candidate causal variants

https://t.co/Af4p41osxf

[CBU @CBUuniTo]

And more posters at #eshg today! Meet Daniela and Davide at P18.116C and P21.001C in the coming session, and Roberta at P21.022D later today!

[CBU @CBUuniTo]

Are you at #eshg2025 in Milan? Come and check out what we are up to! 3 posters from our group in the coming session: Camilla at P18.011.B, Irene at P18.016B and Ettore at P18.131B!

[CBU @CBUuniTo]

Our work on the molecular basis of the genetic correlation between BMI and brain morphology has now appeared in PLOS Genetics

https://t.co/PlaRBctiaG

Thanks to @DFusco17, @CamillaMarinel8, @MathildeAndr11, @LuciaTroiani, Martina Noè, and
@FabrizioPi1139

[CBU @CBUuniTo]

Genetically regulated eRNA expression predicts chromatin contact frequency and reveals genetic mechanisms at GWAS loci

https://t.co/CWb1QAyRyr

[CBU @CBUuniTo]

An atlas of single-cell eQTLs dissects autoimmune disease genes and identifies novel drug classes for treatment

https://t.co/xyuBC5sons