Chris McCormick

Fascinated by RNA viruses.

[Chris McCormick @CMc_positive]

@PolyakSteve Is that CatGPT?

[Chris McCormick @CMc_positive]

@CVRHutchinson An enjoyable minute playing guess that virus. 'Fraid only got F, G and I. Is B bacteriophage? D for Hepatitis Delta to get in virus satellites 🛰️? Great project.

[Chris McCormick @CMc_positive]

Pre-Rydal Hall hill walking back on 👍

[Chris McCormick @CMc_positive]

@SGriffin_Lab @NJTemperton @LIMRLeeds @LeedsMedHealth @UniversityLeeds Well done Steve. Thoroughly deserved.

[Chris McCormick @CMc_positive]

@LabMulvihill Agree there are potentially interesting applications. Just thinking I hope no enthusiastic student thinks of using it to express their GOI thinking it as innocuous as a histag. E.g. using it to express a viral protein that shuts down mammalian translation or NFkB signalling.

[Chris McCormick @CMc_positive]

@LabMulvihill Super cool but after a few days of reflection not necessarily a harmless E.coli expression system. Outer membrane vesicles can deliver their 'payload' to the mammalian cell cytosol. Please consider this when expressing your GOI.

[Chris McCormick @CMc_positive]

OK Microsoft, what are the kindergarden-like icons doing on my work laptop toolbar after the latest update?

[Chris McCormick @CMc_positive]

@DrPKQuashie Thanks Peter! Catching it at some point was almost inevitable. Wishing you a happy new year as well.

[Chris McCormick @CMc_positive]

Not the 12 days of Xmas I wanted; at least symptoms are mild. Wonder if duration of shedding for those who have dodged infection until now has shifted due to viral evolution as was surprised to be +ve for so long, but perhaps I am the outlier instead!

[Chris McCormick @CMc_positive]

@cggbamford 650,000 animals! - that is about the same number of cells in a well of a confluent 6 well plate. I can't help envisaging some kind of mad plaque assay about to take place.

[Chris McCormick @CMc_positive]

@locker_nic I sympathize Nic. My cycling over trousers chose to spring a leak in the crotch today. Currently Southern blotting myself in the office.

[Chris McCormick @CMc_positive]

@SaganLab @weber_lab Thought provoking and provides an attractive concept to perhaps explain how +ve strand viruses are able to shut off translation from foreign IRESes as well as their own; something that still puzzles me.

[Chris McCormick @CMc_positive]

One fear to rule them all, one fear to find them, one fear to bring them all and in the darkness bind them (and the rest of the country if we don't do something about it)
https://t.co/aWKqKoz2In

[Chris McCormick @CMc_positive]

So if 2 PM candidates Tory party members get to decide again. Presumably because they did such a great job first time around 🤦

[Arbovirus Seminars @ArbovirusS]

Excited to announce the 2022-2023 International Virtual Seminar series on Arbovirus Biology! Speakers from a diversity of backgrounds presenting the best in arbovirus science. As a community-driven initiative please help us with a RT! #virology #pathogenesis #immunity #vectors

[RNA @RNAJournal]

Using ribozymes to reveal variation in the folding capacity of [-] RNA; an essential RNA species produced during positive strand RNA virus replication. #RNAfolding #RNAvirus
@MRHerodDR @CMc_positive
https://t.co/XEWGQZTQIb

[Chris McCormick @CMc_positive]

@GroveLab @ScheelLab Great to know it is on again but sad not to be there this year. Please hike a hill for me on Saturday PM. Hope to make it next year 🤞

[Chris McCormick @CMc_positive]

@BrettLindenbach Wishing you a speedy recovery Brett.

[Chris McCormick @CMc_positive]

@cggbamford Thanks for overly generous comment Connor.

[Chris McCormick @CMc_positive]

Sprung from too many debates over conference beers as to the structural state of the replicative intermediates of +ve strand RNA viruses. Enormous thanks to @MRHerodDR @Stonehouse_lab + other Leeds crew for collaborating. Always great to work with!
https://t.co/lj3oj0Zm56