CSHLPress

CSHL Press publishes celebrated books, journals and other media in the fields of genetics, cell and molecular biology.

[CSHLPress @CSHLPress]

How can poly(A) site usage be controlled? This review from the #RNASpecialIssue examines strategies to modulate cleavage and polyadenylation sites, highlighting applications in studying alternative polyadenylation and developing new therapeutic approaches. https://t.co/eU5RDeaLxH

[Genome Research @genomeresearch]

The new issue of @genomeresearch is now live. Follow the link to new research on allele-specific splicing in Alzheimer's disease, tissue-specific gene regulation by vitamin B, and more! https://t.co/3qxVJvJX98

[CSHLPress @CSHLPress]

Can we map miRNAs and their targets in brain tissue? Current spatial transcriptomics methods can't simultaneously measure miRNAs and their target 3′UTRs. This #RNASpecialIssue review explores the challenge and emerging solutions: https://t.co/ODMi8ql49Z #RNABiology #MicroRNA

[CSHLPress @CSHLPress]

RNA function is defined by its interactions. This review from the #RNASpecialIssue highlights new CLIP-based methods to map protein–RNA and RNA–RNA contacts, advancing reconstruction of RNA interaction networks at transcriptome scale.
https://t.co/ja8mbVgCrB

[CSHLPress @CSHLPress]

How well can machine learning predict RNA secondary structure?

This review in the #RNASpecialIssue examines current approaches—from deep learning to hybrid models—while exploring the field’s “generalization crisis” and the rise of RNA foundation models. https://t.co/8fjL9vCVz0

[CSHLPress @CSHLPress]

How well do deep learning models generalize in RNA secondary structure prediction?

This Perspective from the #RNASpecialIssue explores the “generalization gap” limiting current methods and how AI is reshaping RNA structure prediction. https://t.co/ZFzABBUBNC

#Bioinformatics

[CSHLPress @CSHLPress]

Nanopore direct RNA sequencing is reshaping epitranscriptomics — enabling direct detection of RNA modifications and RNA damage across entire transcriptomes with long-read sequencing.
New review from the #RNASpecialIssue:
https://t.co/0jFDl7wHpT
#RNA #Epitranscriptomics #Nanopore

[Myrna Manners @myrnamanners]

Renowned Scientist Nancy S. Wexler Shares Extraordinary Personal and Scientific Journey in New Memoir, My Life, My Science: Pursuing a Cure for Huntington’s Disease https://t.co/nXj54z5tpy @hdfcures @CSHL #HuntingtonsDisease

[Genes & Development @GenesDev]

🚨 NEW ISSUE ALERT!!! 🚨

New Research articles online now at Genes & Development!

Also in this issue, an Outlook on target-directed miRNA degradation, and a Review discussing the recent advances in optogenetics!

Click here to learn more:
➡️ https://t.co/hEKUs6pGNF

[CSHLPress @CSHLPress]

What’s next for RNA biology at system scale? In this #RNASpecialIssue editorial, the editors frame a shift toward quantitative, integrative approaches, highlighting advances in measuring, modeling, and ultimately manipulating RNA across biological systems. https://t.co/vJWzgFULCE

[CSHLPress @CSHLPress]

We're pleased to feature a recent Special Issue of RNA
showcasing advances in system-level RNA biology—from epitranscriptomics and RNA damage to deep learning–driven structure prediction and beyond.
A strong snapshot of where the field is heading. https://t.co/cMCenQTKf0

[CSHLPress @CSHLPress]

The new issue of @genomeresearch is now live. Follow the link to new research on somatic mutant alleles in bulk tumor samples, honey bee gut microbiota, and more! https://t.co/bmubOmvJui

[CSHLPress @CSHLPress]

The new issue of @genomeresearch is now live. Follow the link to new research on chromosome engineering in 8p syndrome, convergent evolution in arid rodents, and more! https://t.co/7apqPqCVYA

[Cold Spring Harbor Laboratory @CSHL]

Genetically vulnerable to Huntington’s Disease, Nancy Wexler devoted her life to ground-breaking work that revealed the HD mutation and produced a test for susceptibility. Now living with HD, Nancy Wexler has a powerful autobiography published by CSHL Press: "My Life, My Science: Pursuing a Cure for Huntington’s Disease". Pre-order from Amazon at https://t.co/ULBdV3jFAE

[CSHLPress @CSHLPress]

The new issue of @genomeresearch is now live. Follow the link to new research on transposable elements in pancreatic cancer, genomic evolution in living fossils, and more! https://t.co/2Wlao7XUPz

[CSHLPress @CSHLPress]

The new issue of @genomeresearch is now live. Follow the link to new research the 3D genome organization in breast cancer, assisted reproductive technology mutation rate, and more! https://t.co/BjHAZb6MQ7

[CSHLPress @CSHLPress]

The new issue of @genomeresearch is now live. Follow the link to new research on wheat centromere adaptation, Quadrupia - a G-quadruplex database, and more! https://t.co/cRiXMrrO5L

[CSHLPress @CSHLPress]

Now Available! “Epigenetics: History, Molecules, and Diseases” cuts through hype to trace the field from its origins to today’s genomic landscape. A clear, authoritative guide to what epigenetics is—and is not. Now in print + eBook formats: https://t.co/mFacvjOkvZ

[CSHLPress @CSHLPress]

Coming Soon: 'Epigenetics: History, Molecules, and Diseases' by John Greally. A clear-eyed, provocative journey through one of biology’s most captivating and misunderstood ideas. Available in print, eBook, and Kindle formats Tuesday, October 21.

[CSHLPress @CSHLPress]

The new issue of @genomeresearch is now live. Follow the link to new research on microglia in neurodegenerative diseases, intron retention in nuclear RNA complexes, and more! https://t.co/n37B5sm4Yn