Excited to share our latest study published in Nucleic Acids Research: https://t.co/ZSFQt4DI57
It’s the cover story for Issue #12! We drew inspiration from Greek mythology to illustrate CTCF’s constant struggle in shaping the 3D genome architecture.
CTCF binding landscape is established by the epigenetic status of the nucleosome, well-positioned relative to CTCF motif orientation https://t.co/FlDw62Vwdj
1/ 🤔 Do #chromatinlooping-mediated promoter-#enhancer interactions drive gene expression? Or is the local enrichment of transcription factors into hubs/#condensates the key factor? Our AC/DC model of gene regulation at bioRxiv https://t.co/ng40XtC8VD provides a new view on this.
We have an opening for a three-year postdoctoral position for a researcher with expertise in machine learning and genome bioinformatics, to work on cancer diagnostics (liquid biopsies). Please apply here: https://t.co/wT5EuK5GmS
Nucleus is looking for a new Editor-in-Chief. Nucleus is a fully Open Access journal by @tandfonline. Application deadline October 18, 2024
Further information including requirements and application process can be found here:
https://t.co/08rwYPDYwQ
Happy to share! Our latest publication in Genome Biology unveils how BORIS/CTCFL epigenetically reprograms transcriptionally inactive intronic CTCF sites into alternative promoters: https://t.co/N5Oygb4JVe
Multi-omics computational analysis unveils the involvement of AP-1 and CTCF in hysteresis of chromatin states during macrophage polarization https://t.co/HeBzB0j4pw
The counterpart congenital overgrowth syndromes Beckwith-Wiedemann Syndrome in human and large offspring syndrome in bovine involve alterations in DNA methylation, transcription, and chromatin configuration https://t.co/QrNmyumJul