Sebastian Holst

Biomarker leader and Sleep Researcher

[Neuroscience News @NeuroscienceNew]

Family Time and Parental Bonding Linked to Better Sleep in Preteens

Researchers analyzing nearly 5,000 children found that those with strong family bonds and high parental engagement were more likely to get sufficient sleep.

Habits like eating dinner together and talking about the next day were linked to longer sleep durations.

On the other hand, children immersed in technology-based interactions or living in homes with frequent conflict slept less.

The data revealed that social connection clusters with high parental engagement had the highest rates of sufficient sleep.

These findings suggest that simple family routines can significantly influence children's sleep health.

The study points to social connectedness as a promising focus for future sleep-related interventions.

[nature @Nature]

Brain shuttles - new technologies to traverse the blood-brain barrier - are showing promise in Alzheimer's, cancer, and more

https://t.co/gHmwB7d0W2

[Sebastian Holst @CamilloHolst]

Excited to share our new preprint detailing how brain pulsations induced by the respiration and cardiac cycle are modulated by sleep intensity. We also show that sleep propensity boosts pulsation strength in the brain parenchyma over CSF-filled ventricles https://t.co/ia2RDiQfZd

[Brain and Sleep Research Laboratory @bsrlaboratory]

Brain clearance is reduced during sleep and anesthesia

https://t.co/sa9ieZN4PI

[Roche @Roche]

✨There is hope that Parkinson's will one day be eliminated. Recognition of the importance of certain protein formations has brought us to the brink of a revolution.

The goal: personalise medicine for each patient. 🌈

Check it out: https://t.co/ZHqaQwfhXl

[Sleep Research Society @ResearchSleep]

Overall, #sleep deprivation altered the timing of #puberty in both animal and human models but in different directions. https://t.co/xwPp1VtVqq #obesity

[Azad Bonni @AzadBonni]

Interested in postdoctoral training in fundamental neurobiology in an environment of a world-leading R&D unit, apply to have the best of both worlds! Please RT 1/5

[Alexandra Vallet @AValletResearch]

Check this new paper about the effect of sleep deprivation and NREM sleep stage on physiological brain pulsations in humans! https://t.co/kIGw1QAIOp

[Novo Nordisk Foundation @novonordiskfond]

Many children and young people sleep less than recommended. A new research collaboration between @koebenhavns_uni and @Rigshospitalet will study the effect of sleep extension on weight, metabolism and learning in 6 – 9-year-old children.
https://t.co/PHul5KxX6O

[Masud Husain @MasudHusain]

This month's @Brain1878 contains a set of important articles on #Parkinsons and #LewyBody dementia, including reviews on alpha-synuclein and bradykinesia, papers on cholinergic loss, mechanisms underlying rigidity, impulse control disorder and cognition https://t.co/7VrjxBlByJ

[FENS @FENSorg]

🤩 Here’s a tip to avoid #FOMO at the #eSleepEurope23: check now the #FENS and @ESRS_Sleep joint session and meet the outstanding speakers: Umberto Olcese, @BandarabadiM, Dragana Rogulja, Lior Appelbaum, @ChaBoccara and @svenjabrodt.

👉 More info: https://t.co/rUzk40XNML

[ESRS @ESRS_Sleep]

🌟 Exciting news!
Introducing the first #ESRSPaediatricSleepSchool, 11-13 April, 2024, Bertinoro Castle, Italy. Learn from global experts in #Paediatric #Sleep medicine. Ideal for clinicians, researchers, and trainees. Applications open this fall.
🔗https://t.co/De2p2roILB

[American Academy of Sleep Medicine @AASMorg]

This is the first study to develop tailored sleep hygiene guidelines for #ShiftWorkers. https://t.co/9s9mdxUa6S

[Society for Research on Biological Rhythms @SRBR_Outreach]

Circadian cycles orchestrate many functions of the immune system. Find out a bit about how this was discovered and what new research is telling us about circadian immunity in this featuring @McKeatingLab @LM_Ince @jkimmey @gibbs_lab_UoM:

https://t.co/m5bIVzgg6n

#sciencesunday

[American Academy of Sleep Medicine @AASMorg]

Being a #NightOwl can be costly to physical health, emotional well-being, cognitive function, productivity, financial well-being, self-esteem, relationships, and safety. These strategies may help night owls fall asleep and wake up earlier. https://t.co/evfq874kN3

[Neuroscience News @NeuroscienceNew]

“Sweet” Research Sheds Light on Glucose Metabolism in Neurons

Neurons in the brain directly metabolize glucose to function normally, contrary to previous beliefs that glial cells metabolized the sugar and indirectly fuel neurons. The findings could provide insights into the development of new therapeutic approaches for neurodegenerative diseases like Alzheimer's and Parkinson's, where the brain's uptake of glucose decreases in the early stages of the diseases.

#neuroscience

https://t.co/joTK2qbwdn

[Sleep Research Society @ResearchSleep]

Two doses of an FDA-approved sleeping pill reduced levels of #Alzheimers proteins in a small study of healthy volunteers led by researchers at @WUSTLmed. Much more work needs to be done to confirm the viability of such an approach. https://t.co/GlJZON06Pt #sleep

[Noain Lab @DanielaNoain]

We are hiring! Hey, recent graduate masters in biomedical engineering or related field eager to learn about Sleep and Neurodegeneration, get in touch! We are searching for you😃

https://t.co/uF8EWfGjpO

[Ingentium Parkinson's Disease @Ingentium_PD]

Sodium Oxybate in Treatment-Resistant REM Sleep Behavior Disorder. https://t.co/PTpJ7zxOnu

[Sebastian Holst @CamilloHolst]

We are looking for a motivated and passionate candidate to investigate circadian effects of jetlag via an in-house developed meta-regression database based on published human studies. The position is a fully funded 7 month Roche RiSE internship.
https://t.co/z5I0FBZsLM