Jake Scott

@CWRUSOM @OxUniMaths @ClevelandClinic Sarcoma #radonc #mathonco #mathevo @NavalAcademy submarine #veteran tweets=mine he/him TEDMED

[Jake Scott @CancerConnector]

🚨 New in @JClinInvest 🚨
HPV+ oropharynx patients do not all benefit equally from the same radiation dose.
Our study shows that genomics (via GARD) can guide personalized RT de-escalation—safely sparing toxicity without losing cure.
Paper 👉 https://t.co/TEOh9q6qYQ
#ASTRO25

[Amy Xu, MD PhD @AmyXuMDPhD]

✨ Inspiring to see @imrtlee representing ☢️ radiation oncology on the ASCO main stage.

Practice changing work reducing treatment toxicities and integrating radiographic biomarkers to personalize radiation

@MSK_RadOnc @MSKCancerCenter
#ASCO26 #RadOnc

[Amy Xu, MD PhD @AmyXuMDPhD]

🧬 Can tumor genomics be used to personalize radiation dose?

Grateful to present results from our phase II trial on dose de-escalated radiation therapy for ATM altered tumors at #ASCO2026

Great to see ☢️ #Radiation in the early-phase #PrecisionOncology space!

[Jeffrey West @mathoncbro]

Our "evolutionary antifragile therapy" paper is now posted online (Cancer Research):
https://t.co/QyGexLImV2

First experimental validation of antifragility in cancer (ALK inhibitors in lung)! An awesome collaboration involving @ara_anderson, @AndriyMarusyk, @Binadesai14 et al

[Rahat Malhotra @_rahatmalhotra_]

Re-irradiation planning is now in RadRisk v2.0 🧵
Enter two RT courses (or upload DVHs), pick your OAR, and get cumulative BED + EQD₂ with time-discounted repair via the ReTEC model (Grimm 2026).
https://t.co/QMCMXwje20
#RadOnc #Reirradiation #SBRT #MedPhys #RadiationOncology

[Jake Scott @CancerConnector]

Our comment on recent excellent @NatureGenet paper from @naxerova

Age identifies cancer drivers hidden within the genome

https://t.co/WgfqPacjES

[Jake Scott @CancerConnector]

The figure below is my attempt to tell that story. We’re still learning how best to use this information. But the core idea is no longer theoretical: tumor genomics can help quantify the biological effect of radiation and bring that information into real treatment decisions. 8/n

[CWRU Physics @PhysicsCWRU]

Scientific American recently featured research from CWRU Physics' COMPACT collaboration, led by Professor Glenn Starkman, exploring alternative cosmic topologies and challenging the assumption that our universe is flat and infinite.

Read more: https://t.co/CiAbGzlkxp

#CWRU

[Vivek Subbiah, MD @VivekSubbiah]

🚨⭐️HOT off the press 👉Our Editorial in @NatRevDrugDisc Nature Reviews Drug Discovery is out TODAY, publishing simultaneously with @ASCO #ASCO26 meeting! 🎉
👉"Closing the Paediatric gap in cancer drug development: a call to industry"
👉Delighted to publish this with my amazing friend & co-author @CuglievanBranko @UTMDAnderson
👉This piece is close to my heart 👉 A call to action on closing the pediatric oncology drug development gap.
👉Children with cancer deserve the SAME urgency, the SAME rigor, and the SAME speed as adults @NaturePortfolio
👉Please share this because this message widely as needs to be heard.
👉And a very special thank you to the brilliant Editor-in-Chief, Dr. Peter Kirkpatrick, who published this with newspaper speed. That is why Nature Reviews Drug Discovery has an impact factor > 100+ 🙏
👉To every patient & family who has waited too long this one's for you @OncoAlert @oncodaily @OpenMedicineHQ
Link: https://t.co/hYwrgiCFnV

[Jake Scott @CancerConnector]

@baym Also it seems like putting bugs INTO the place where the compute is happening is antithetical to good coding practice. What would Emily Noether say?! #WWENS

[Jame Abraham, MD, FACP @jamecancerdoc]

Congratulations to Christina Chukri and Ryan Kolonick - our two young researchers @ClevelandClinic for presenting @ASCO #asco26 Implementation of a CRC led clinical trial model in early phase trials

[Steven Strogatz @stevenstrogatz]

If you like thinking about what math can do for biology and vice versa, you might like this public talk I gave a year ago. It contains a lot of stories from my own life. "From Math to Bio and Back: Reflections on a Two Way Street" https://t.co/TzKE3jnK29

[Dr. Anthony Letai @NCIDirector]

At AACR last month, I received many questions about grant applications. Today on @theNCI Bottom Line blog, I’m providing straight answers on where things stand, and what we’re doing to fund the best science as swiftly as possible: https://t.co/yj6CIQXYVb

[Drew Moghanaki @DrewMoghanaki]

And then there were 6 Gold Medals for UCLA Radiation Oncology!

1) Dan Low 🥇
2) David Beyer 🥇
3) Michael Steinberg 🥇
4) Bill McBride 🥇
5) Rodney Withers 🥇
6) Robert Parker 🥇

#MyLifeWithDanLow

[Jake Scott @CancerConnector]

It should be noted that the @dtbergman - a rising PGY-3 at MSKCC #RadOnc led this work. The future is bright!!

[Jake Scott @CancerConnector]

Did you know that nearly half of all cancer cures involve #RadiationTherapy? and yet we're largely left out of #PrecisionMedicine discussions.

🧵 1/n: new preprint opening the door for precision radiation oncology adoption through RNAseq-based #GARD

https://t.co/iEVjgLNSd4

[Drew T Bergman, MD @dtbergman]

Privilege to work with Jake (@CancerConnector) et al. to make sure we carefully translate RSI into the clinical NGS era to enable biologically-informed radiotherapy. Please get in touch to team up for clinical validation and to join the GARD Working Group!

[Jake Scott @CancerConnector]

See also a more detailed discussion on LinkedIn. End 🧵 9/9

https://t.co/dX1uHsj5Lr

[Jake Scott @CancerConnector]

Did you know that nearly half of all cancer cures involve #RadiationTherapy? and yet we're largely left out of #PrecisionMedicine discussions.

🧵 1/n: new preprint opening the door for precision radiation oncology adoption through RNAseq-based #GARD

https://t.co/iEVjgLNSd4

[Jake Scott @CancerConnector]

The figure below is my attempt to tell that story. We’re still learning how best to use this information. But the core idea is no longer theoretical: tumor genomics can help quantify the biological effect of radiation and bring that information into real treatment decisions. 8/n