A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis by @CaraAdolph, Chen-Yi Cheung, Gregory M. Cook et al at @otago@microtago@MWC_CoRE https://t.co/UcNV58XUlo
Our latest work reporting that antibiotic resistance produces collateral drug phenotypes in Mtb is now published online in @NatureComms
https://t.co/N2ZUy1KJNc
In @Nature today (open access), we report the structural and mechanistic basis of how bacteria harvest energy from air. We reveal a novel enzyme, Huc, consumes atmospheric levels of hydrogen gas and transfers the derived electrons for aerobic respiration. https://t.co/5J0Pq1mS7l
New preprint investigating drug-resistance in M. tuberculosis. Fantastic effort from PhD candidate Natalie Waller and all involved. https://t.co/H42XuOucwe
Excited to share the first paper from my PhD work out now in @mbiojournal 🎉 Here, we characterise the role of succinate dehydrogenase in the physiology and drug susceptibility of M.#tuberculosis. Thanks to my supervisors @cooklabuoonz & @mattmcneil86
https://t.co/WxJQ0JQv10
Derivatives of FDA-approved amiloride eliminate drug-resistant M. tuberculosis in vitro by interfering with bacterial energy conservation: https://t.co/sfE7F7TKWh @cooklabuoonz