🚨 New paper from our lab @CardosoLab
We review how voltage-gated ion channels drive neuronal dysfunction in motor neuron disease—and why targeting channel gating may unlock new therapeutic strategies.
A must-read for neurodegeneration & ion channel biology 👇
https://t.co/wj8yQUqYxl
#ALS #MND #IonChannels #Neuroscience #DrugDiscovery
🕷️The @CardosoLab recently published two intersting studies on spider-venom peptides targeting Nav channels, Open Access @Toxins_MDPI and Biochemical Pharmacology. Our findings support the hypothesis that Nav-targeting pharmacophores represent an evolutionarily ancient molecular feature of spider venoms @IMBatUQ@UQ_News
PMID: 41295876
PMID: 41319925
Calling all Venom Research Fellows! Don’t miss this exciting meeting in Brasília, December 11–14, 2024. It’s a fantastic opportunity to connect and share insights on venom-derived drugs. I hope to see you there!
👩🏻🔬🐍🕷️🦂🐝🔬💊
I am pleased to share this fantastic collaborative effort by @CardosoLab@CNZdenek @insect_venomics investigating venom evolution in Reduvvidae smarting out neofunctionalization of toxins from cytolytic and pain-inducing to pain-free anticoagulant activity.
@IMBatUQ@CellPressNews
Venom exaptation and adaptation during the trophic switch to blood-feeding by kissing bugs: iScience https://t.co/tlt55Ux3VR
Our lab's latest research is out in ToxiconX. We've pioneered a cutting-edge High-content fluorescence bioassay that accurately discerns between pore formation, ion channel modulation, and cell membrane lysis induced by venom components.
👉https://t.co/wSLliQLa6L
🐍🕷️ @CardosoLab@IMBatUQ
Could venoms one day be used to treat neurodegeneration?
In a recent interview, we asked @DrFeCardoso about @CardosoLab's latest research, their involvement in #MotorNeuronDiseases, and the future of this work.
Read the interview here: https://t.co/i3fLXZoXnr
I'm thrilled that @NanionTech has spotlighted my research on venom-based drug discovery in this podcast. This fuels my passion for innovation and the groundbreaking potential of venom in modern medicine @CardosoLab@IMBatUQ 🕷️🐍🧠
https://t.co/jETWd8kzHZ
🎉Our lab is immensely proud of postdoc Jessica for winning the award for best ECR talk at the IST World Congress in Singapore! Special thanks to @sophionbio for providing travel support ����🕷️🔬🧠💊
@DrFeCardoso @IMBatUQ
To mark #InternationalWomensDay , the #NatureReviews Collection on women's health has been updated. Click here to read articles on various aspects of women's health, including a hot-off-the-press Review on heart failure therapies from @NatRevCardiol: https://t.co/754WwJltgC
By wirelessly recording signals from deep-brain stimulators in patients with Parkinson's disease in an outpatient setting, Soh et al. show that the STN – known for its role in motor control – also exerts control over non-motoric, attentional processes. https://t.co/kfDhh86sQi
AlphaFold2 and RoseTTAFold are limited to predicting the 3D structure of proteins. A new all-atom method models complete biomolecular assemblies, including proteins, nucleic acids, small molecules, metals, and covalent modifications. #NBThighlight https://t.co/a9relIlKLC
Will we witness an AlphaFold moment for functional protein engineering and design? Will we solve the protein design problem — that is, the ability to create tailor-made functional proteins on demand — once and for all? https://t.co/4jEsOrsMDk
https://t.co/THTRRTnnDn