Después de más de 7 años ejerciendo como psicólogo, veo que muchas parejas se enfrían en menos de 2 años.
No es el estrés, ni los niños, ni la edad.
Son estos 5 conceptos…
ESNR Case of the Month: A Rare Midbrain Tumour
Presented by Dr May Ting Tan. Our first-ever Case of the Month features a 21-year-old with a tectal plate lesion. MRI clues pointed the way, but biopsy confirmed a midbrain germinoma. Stay tuned 🧠
Clinical pearl:
Hypophysitis + diabetes insipidus + hypertrophic pachymeningitis is a pattern.
Once infection & malignancy are excluded, this triad should narrow your thinking to two diagnoses:(keep sarcoid and AAV in mind)
IgG4-related disease
→ Fibro-inflammatory, steroid-responsive
• Pachymeningitis + hypophysitis are classic
• DI common
• Disease of the coverings (dura, skull base, pituitary)
• Brain parenchyma usually spared
Erdheim–Chester disease (ECD)
→ Histiocytic, often steroid-refractory
• DI very common
• Pachymeninges + parenchymal CNS involvement
• Brainstem & cerebellum > hemispheres
• Cerebellar atrophy / neurodegeneration may be seen
• Multisystem involvement common
🧠 Why rheumatologists care:
👉 One responds dramatically to steroids
👉 The other needs targeted therapy (BRAF/MEK)
Rule of thumb:
Parenchymal or degenerative CNS disease tips the diagnosis toward ECD.
#Rheumatology #NeuroRheum #IgG4RD #ErdheimChester #ClinicalReasoning #MedTwitter @DrAkhilX @IhabFathiSulima@CelestinoGutirr@DurgaPrasannaM1
Need a DURABLE way to remember what causes DURAL enhancement?
Feeling left behind when it comes to leptomeningeal disease?
Here’s an easy way to remember the differential diagnoses for the two types of meningeal enhancement:
LEPTOMENINGEAL
Remember:
L = Leakage (subarachnoid hemorrhage)
E = Epilepsy (recent seizure)
P = Pus (infection, either bacterial, viral or granulomatous/fungal)
T = Tumor (leptomeningeal metastatic dz)
O = Operation (post operative)
PACHYMENINGEAL
Remember
P = Puncture (recent LP), Pus (subdural empyema)
A = Autoimmune (sarcoidosis, IgG4)
C = Craniotomy (post-op), Chronic subdural
H = Hypotension (intracranial hypotension)
Y = You’ve got a mass (mets, usually from direct bony extension, meningioma)
Now you’ve got a lot information PACH-ed into an easy & memorable mnemonic!
Septiembre con S de:
"Si sus sentimientos son los mismos que en abril, dígalo de una vez.
Mi afecto y mis deseos no han cambiado, pero una palabra suya me silenciará para siempre".