Carol N. Rizkalla, MD

PGY4 AP/CP @UWlabmedpath 🇺🇸 26-27 @StanfordPath #GYNpath fellow 😍 @RCSI_irl 22 alum 🇮🇪 Creator of #PathWebinarPearls 🧵I Trainee #PathTweetAward 23&24

[Carol N. Rizkalla, MD @Carol2Path]

I am a huge proponent of educational webinars for learning 🧠 #PathWebinarPearls

👇👇👇is a compiled list of societies that regularly host educational webinars- many of which I have listened to myself! Most of these are FREE for residents, you may need to register as a member.

[Ankur Sangoi @slusagar]

#GUpath TURBT from today's signout showing what I call "3/4 rule" of MP invasion

(if tumor is three-quarters of the way around MP bundle but not technically IN bundle, I'll still call it MP invasion)

for good measure, lower power shots show more typically pattern MP invasion

[Ankur Sangoi @slusagar]

#GUpath🧩time!

80ish M undergoes TURP

❓🔬🤔

[Ankur Sangoi @slusagar]

I'm honored to receive this @StanfordPath award!

helps solidify my mantra:
#ABT (always be teaching)

also, go #GUpath‼️💪🏼🔬

[Janira Navarro @Janiranavarro]

Routine minimum IHC for metastatic tumors - prostate cancer

- Prostate markers: NKX3.1, AR
- Neuroendocrine markers: Synaptophysin, chromogranin, and INSM1
- Others to consider: Ki67, p53, RB

Per NCCN, all metastatic biopsies should undergo NGS testing.

Dr. Chan #USCAP2026 #pathology #PathX #PathTwitter

[Kamran Mirza MD PhD - کامران مرزا @KMirza]

A little over two years ago, I stood in front of the @LoyolaStritch Class of 2026 as their M2 pathology instructor before heading to Michigan. Last week, I had the profound honor of returning to deliver their commencement address. Full circle in the best possible way.

I spoke to them about curiosity, wonder, resilience. About the bone marrow, of course (I promise it made sense).

I want them to remember that medicine is still sacred work. In a world moving faster and louder every day, I hope they protect the part of themselves that still pauses in awe at the privilege of caring for another human being.

To the Stritch School of Medicine Class of 2026: thank you for allowing me to be a small part of your journey, both then and now. Watching you cross that stage was a privilege I will never forget.

Never stop exploring.

https://t.co/LZSekkcIYy

[GU Pathology Society (GUPS) @GU_Path_Society]

📣 Join us for the next @GU_Path_Society Virtual Education Series!

🧬 Tumor Staging in GU Pathology (Part 1)
📅 June 23, 2026 | ⏰ 12–1:30 PM EST

Featuring: 👨‍⚕️ Dr. Tekin @buraktekinmd
👨‍⚕️ Dr. Sangoi @slusagar
👩‍⚕️ Dr. Siegmund

Register now 👉 https://t.co/WagaqUpESt

[Ankur Sangoi @slusagar]

#GUpath orchiectomy w/embryonal carcinoma showing LVI in main specimen

spermatic cord shows discontinuous (non LVI here) involvement

current AJCC calls this pM1, but NCCN seemingly blows this off, saying to instead stage as pT3

🤔🔬🙈⁉️

⏬cont'd⏬

[Ankur Sangoi @slusagar]

#GUpath: adult M, renal mass bx

before you embark down growing DDx of pink renal tumors, don't forgot about angiomyolipoma!

IMO, cathepsinK is the best #IHCpath here,
> than melanA/HMB45

[Fouad Boulos @fouad_boulos]

Yet another sneaky treacherous one...

Keep your eyes wide open, children.

#breastpath

[Ankur Sangoi @slusagar]

first time trainee sees his/her paper out in press

[Charlie Herndon @DrCycloPath]

#PathQuiz 🔬🧬

A) Chromophobe RCC
B) Oncocytoma
C) SDH-Deficient RCC
D) Low-grade Oncocytic Tumor

#Pathology #GUPath #KidneyPath

[Guan-Nan Zhang ，张冠楠，MD, PhD @GuannanTiffany]

🧩 Bloody Bladder
When signing out this lesion, what clinical question comes to mind?

👨 65-year-old man
• Prior prostate adenocarcinoma?
👩 45-year-old woman
• Prior cervical carcinoma?
not always.

So… what’s the diagnosis? 🤔
#DxMindMap #BladderTumor #PathTwitter #JHUPath

[Ankur Sangoi @slusagar]

while not formally staged since not "carcinoma", rarely can you get "pT3a" histology🔬
(vascular/adipose/pelvicalyceal invasion)

doesn't change Dx!
(but if occurs, probably worth confirming Dx by doing NGS to rule out DDx entities)

PMID: 38422612

[Janira Navarro @Janiranavarro]

60 yo with diverticulitis and peritoneal nodule

Final diagnosis: Submesothelial fibroblasts with keratin expression (keratin IHC pic 3)

The cells can also coexpress desmin. They are a normal finding and reactive change and should not be interpreted as carcinoma.

Dr. Fritchie #USCAP2026 #PathX #pathology #PathTwitter

[Janira Navarro @Janiranavarro]

45 yo female with a "bump" in tongue
Subsite not given

Pale intraepithelial structures (CK7+) with underlying S100+ spindle cells and chronic inflammation

Diagnosis: Normal taste bud (circumvallate papilla)

- Normal taste buds appear as pale structures on HE (CK7 +, Pic 2)
- S100+ spindle cells and chronic inflammation are expected underneath, Pic 3
- Most prominent in circumvallate papillae (posterior tongue)
- Do not mistake for Paget disease or neural neoplasm

Dr. Cipriani #USCAP2026 #PathX #PathTwitter

[Charlie Herndon @DrCycloPath]

✅ Endometrial atypical hyperplasia / EIN 🎯
• Defined as a geographical lesion where the glandular volume exceeds the stromal volume.
• Shows significant cytological atypia (loss of polarity, rounded nuclei) distinct from background glands.
• It is a clonal proliferation and a direct precursor to low-grade endometrioid adenocarcinoma.
• Often associated with loss of PTEN or PAX2 expression.

[Janira Navarro @Janiranavarro]

Endometrial Adenocarcinoma: Depth of Invasion – Challenging scenarios 🔬

✅ Avoid the cornu – naturally thinner, can lead to over-staging

✅ Tumor in a leiomyoma? Include it in your invasion measurement if it’s the deepest point

✅ Invasion from adenomyosis in outer half? Stage as pT1b (per ICCR & ISGyP).

Dr. Joehlin / Dr. McGregor - Short course #USCAP2026 #pathology #PathX #PathTwitter

[International Society of Gynecologic Pathologists @ISGynP]

The International Society of Gynecological Pathologists Education Committee proudly congratulates the recipients of ISGyP trainee presentation awards at USCAP Texas, March 2026! 🎉👏 #Pathology #Gynaepath #Gynpath #PathTwitter

[Ankur Sangoi @slusagar]

no better way to start a Monday than with #beautyinb9 #GUpath nephrogenic adenoma!

simple prostatectomy for BPH, remote h/o 3+3 prostatic adenocarcinoma

[Charlie Herndon @DrCycloPath]

#PathQuiz 🔬🦴
_______ rearrangement
A) USP6
B) FN1
C) COL12A1
D) GRM1

#Pathology #SoftTissuePath #BonePath #MolecularPath
Clue in caption 🧐
@IARCWHO